Development of amorphous solid dispersion formulations of a poorly water-soluble drug, MK-0364

International Journal of Pharmaceutics

Volumn 452, Issue 1-2, 2013, Pages 73-81

  Sotthivirat, S ^a   McKelvey, C ^a   Moser, J ^a   Rege, B ^a   Xu, W ^a   Zhang, D ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Copovidone; Hot melt extrusion; HPMCAS; MK 0364; Solid dispersion; Spray drying

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; TARANABANT;

AREA UNDER THE CURVE; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SOLUBILITY; GLASS TRANSITION TEMPERATURE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SPRAY DRYING; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY POWDER DIFFRACTION;

EID: 84884137626     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.037     Document Type: Article

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