Currently used pesticides and their mixtures affect the function of sex hormone receptors and aromatase enzyme activity

Toxicology and Applied Pharmacology

Volumn 272, Issue 2, 2013, Pages 453-464

  Kjeldsen, Lisbeth Stigaard ^a   Ghisari, Mandana ^a   Bonefeld Jørgensen, Eva Cecilie ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Antiandrogenic; Aromatase; Endocrine disruptor; Estrogenic; Luciferase reporter gene assay; Pesticide

Indexed keywords

2 (4 CHLORO 2 METHYLPHENOXY)ACETIC ACID; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANDROSTENEDIONE; AROMATASE; BITERTANOL; CHLORMEQUAT; CIPERMETHRIN; ESTROGEN RECEPTOR; IODOSULFURON METHYL SODIUM; MALATHION; MANCOZEB; MESOSULFURON METHYL; METABOLITE ETHYLENE THIOUREA; METRIBOLONE; METSULFURON METHYL; PESTICIDE; PROPICONAZOLE; PROTHIOCONAZOLE; TAU FLUVALINATE; TERBUTYLAZINE; THIFENSULFURON METHYL; UNCLASSIFIED DRUG;

ANIMAL CELL; AROMATIZATION; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CHEMICAL STRUCTURE; COMPUTER MODEL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PROTEIN CONTENT; REPORTER GENE; STEROIDOGENESIS; TRANSACTIVATION;

17Β-ESTRADIOL; 2-METHYL-4-CHLOROPHENOXYACETIC ACID; 4-ANDROSTEN-4-OL-3,17-DIONE; 4-AOD; ANDROGEN RECEPTOR; ANTIANDROGENIC; AR; AROMATASE; CA; COEFFICIENT OF VARIATION; CONCENTRATION ADDITION; CV; CYP; CYTOCHROME P450; DDE; DDT; DHT; DICHLORODIPHENYLDICHLOROETHYLENE; DICHLORODIPHENYLTRICHLOROETHANE; DIHYDROTESTOSTERONE; DIMETHYL SULFOXIDE; DMSO; E2; ED; EDC; ENDOCRINE DISRUPTOR; ENDOCRINE-DISRUPTING CHEMICAL; ENDOCRINE-DISRUPTING/ENDOCRINE DISRUPTION; ER; ESTROGEN RECEPTOR; ESTROGENIC; ETHYLENE THIOUREA; ETU; HF; HYDROXYFLUTAMIDE; LUCIFERASE REPORTER GENE ASSAY; MCPA; METHYLTRIENOLONE; PESTICIDE; QSAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; R1881; SC; SD; SOLVENT CONTROL; STANDARD DEVIATION;

ANIMALS; AROMATASE; CELL LINE, TUMOR; CELL SURVIVAL; CHO CELLS; COMPLEX MIXTURES; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; HUMANS; PESTICIDES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; TRANSCRIPTIONAL ACTIVATION;

EID: 84884135242     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.06.028     Document Type: Article

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