메뉴 건너뛰기




Volumn 454, Issue 1, 2013, Pages 425-434

Cholic acid modified N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride for superoxide dismutase delivery

Author keywords

Chitosan; Drug delivery; Nanoparticles; Protein

Indexed keywords

CHITOSAN DERIVATIVE; CHOLIC ACID; MALONALDEHYDE; N (2 HYDROXY) PROPYL 3 TRIMETHYLAMMONIUM CHITOSAN CHLORIDE; NANOPARTICLE; SUPEROXIDE DISMUTASE; TRIMETHYLAMMONIUM SALT DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84884130933     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.06.056     Document Type: Article
Times cited : (33)

References (51)
  • 4
    • 77955276767 scopus 로고    scopus 로고
    • The characteristics, cellular uptake and intracellular trafficking of nanoparticles made of hydrophobically-modified chitosan
    • Chiu, Y.L., Ho, Y.C., Chen, Y.M., Peng, S.F., Ke, C.J., Chen, K.J., Mi, F.L., Sung, H.W., 2010. The characteristics, cellular uptake and intracellular trafficking of nanoparticles made of hydrophobically-modified chitosan. J. Control. Release 146, 152-159.
    • (2010) J. Control. Release , vol.146 , pp. 152-159
    • Chiu, Y.L.1    Ho, Y.C.2    Chen, Y.M.3    Peng, S.F.4    Ke, C.J.5    Chen, K.J.6    Mi, F.L.7    Sung, H.W.8
  • 5
    • 33750284918 scopus 로고    scopus 로고
    • Synthesis and physicochemical and dynamic mechanical properties of a water-soluble chitosan derivative as a biomaterial
    • DOI 10.1021/bm060436s
    • Cho, J., Grant, J., Piquette-Miller, M., Allen, C., 2006. Synthesis and physicochemical and dynamic mechanical properties of a water-soluble chitosan derivative as a biomaterial. Biomacromolecules 7, 2845-2855. (Pubitemid 44615269)
    • (2006) Biomacromolecules , vol.7 , Issue.10 , pp. 2845-2855
    • Cho, J.1    Grant, J.2    Piquette-Miller, M.3    Allen, C.4
  • 6
    • 77649294324 scopus 로고    scopus 로고
    • Intracellular delivery of a membrane-impermeable enzyme in active form using functionalized gold nanoparticles
    • Ghosh, P., Yang, X.C., Arvizo, R., Zhu, Z.J., Agasti, S.S., Mo, Z.H., Rotello, V.M., 2010. Intracellular delivery of a membrane-impermeable enzyme in active form using functionalized gold nanoparticles. J. Am. Chem. Soc. 132, 2642-2645.
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 2642-2645
    • Ghosh, P.1    Yang, X.C.2    Arvizo, R.3    Zhu, Z.J.4    Agasti, S.S.5    Mo, Z.H.6    Rotello, V.M.7
  • 7
    • 0032830995 scopus 로고    scopus 로고
    • On-off control of enzymatic activity synchronizing with reversible formation of supramolecular assembly from enzyme and charged block copolymers [12]
    • DOI 10.1021/ja9919175
    • Harada, A., Kataoka, K., 1999. On-Off control of enzymatic activity synchronizing with reversible formation of supramolecular assembly from enzyme and charged block copolymers. J. Am. Chem. Soc. 121, 9241-9242. (Pubitemid 29477401)
    • (1999) Journal of the American Chemical Society , vol.121 , Issue.39 , pp. 9241-9242
    • Harada, A.1    Kataoka, K.2
  • 8
    • 0344643075 scopus 로고    scopus 로고
    • Antioxidative effect of chitosan on chronic carbon tetrachloride induced hepatic injury in rats
    • DOI 10.1016/S0300-483X(03)00003-9
    • Jeon, T.I., Hwang, S.G., Park, N.G., Jung, Y.R., Shin, S.I., Choi, S.D., Park, D.K., 2003. Antioxidative effect of chitosan on chronic carbon tetrachloride induced hepatic injury in rats. Toxicology 187, 67-73. (Pubitemid 36385054)
    • (2003) Toxicology , vol.187 , Issue.1 , pp. 67-73
    • Jeon, T.I.1    Hwang, S.G.2    Park, N.G.3    Jung, Y.R.4    Shin, S.I.5    Choi, S.D.6    Park, D.K.7
  • 9
    • 2142760512 scopus 로고
    • Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems
    • Kalyanasundaram, K., Thomas, J.K., 1977. Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems. J. Am. Chem. Soc. 99, 2039-2044.
    • (1977) J. Am. Chem. Soc. , vol.99 , pp. 2039-2044
    • Kalyanasundaram, K.1    Thomas, J.K.2
  • 11
    • 37349034239 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases
    • DOI 10.1111/j.1471-4159.2007.04997.x
    • Keating, D.J., 2008. Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases. J. Neurochem. 104, 298-305. (Pubitemid 350293877)
    • (2008) Journal of Neurochemistry , vol.104 , Issue.2 , pp. 298-305
    • Keating, D.J.1
  • 12
    • 19944366963 scopus 로고    scopus 로고
    • Enhancing effect of chemically conjugated deoxycholic acid on permeability of calcitonin in Caco-2 cells
    • DOI 10.1002/ddr.10423
    • Kim, S., Lee, H., Lee, S., Kim, S.K., Lee, Y.-K., Chung, B.H., Moon, H.T., Byun, Y., 2005. Enhancing effect of chemically conjugated deoxycholic acid on permeability of calcitonin in Caco-2 cells. Drug Dev. Res. 64, 129-135. (Pubitemid 40756866)
    • (2005) Drug Development Research , vol.64 , Issue.2 , pp. 129-135
    • Kim, S.1    Lee, H.2    Lee, S.3    Kim, S.K.4    Lee, Y.-K.5    Chung, B.H.6    Moon, H.T.7    Byun, Y.8
  • 13
    • 67651155772 scopus 로고    scopus 로고
    • The inhibition of glioma growth in vitro and in vivo by a chitosan/ellagic acid composite biomaterial
    • Kim, S., Gaber, M.W., Zawaski, J.A., Zhang, F., Richardson, M., Zhang, X.A., Yang, Y.Z., 2009. The inhibition of glioma growth in vitro and in vivo by a chitosan/ellagic acid composite biomaterial. Biomaterials 30, 4743-4751.
    • (2009) Biomaterials , vol.30 , pp. 4743-4751
    • Kim, S.1    Gaber, M.W.2    Zawaski, J.A.3    Zhang, F.4    Richardson, M.5    Zhang, X.A.6    Yang, Y.Z.7
  • 14
    • 77649275722 scopus 로고    scopus 로고
    • A chitosan/β-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer
    • Kim, S., Nishimoto, S.K., Bumgardner, J.D., Haggard, W.O., Gaber, M.W., Yang, Y.Z., 2010. A chitosan/β-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer. Biomaterials 31, 4157-4166.
    • (2010) Biomaterials , vol.31 , pp. 4157-4166
    • Kim, S.1    Nishimoto, S.K.2    Bumgardner, J.D.3    Haggard, W.O.4    Gaber, M.W.5    Yang, Y.Z.6
  • 15
    • 0031185488 scopus 로고    scopus 로고
    • Fluorescence and light-scattering studies on the formation of stable colloidal nanoparticles made of sodium sulfonated polystyrene ionomers
    • Li, M., Jiang, M., Wu, C., 1997. Fluorescence and light-scattering studies on the formation of stable colloidal nanoparticles made of sodium sulfonated polystyrene ionomers. J. Polym. Sci. B - Polym. Phys. 35, 1593-1599. (Pubitemid 127709896)
    • (1997) Journal of Polymer Science, Part B: Polymer Physics , vol.35 , Issue.10 , pp. 1593-1599
    • Li, M.1    Jiang, M.2    Wu, C.3
  • 16
    • 77953809953 scopus 로고    scopus 로고
    • Use of glycol chitosan modified by 5β-cholanic acid nanoparticles for the sustained release of proteins during murine embryonic limb skeletogenesis
    • Li, T.S., Longobardi, L., Granero-Molto, F., Myers, T.J., Yan, Y., Spagnoli, A., 2010. Use of glycol chitosan modified by 5β-cholanic acid nanoparticles for the sustained release of proteins during murine embryonic limb skeletogenesis. J. Control. Release 144, 101-108.
    • (2010) J. Control. Release , vol.144 , pp. 101-108
    • Li, T.S.1    Longobardi, L.2    Granero-Molto, F.3    Myers, T.J.4    Yan, Y.5    Spagnoli, A.6
  • 17
    • 0346155917 scopus 로고    scopus 로고
    • Synthesis and antimicrobial activity of a water-soluble chitosan derivative with a fiber-reactive group
    • DOI 10.1016/j.carres.2003.10.024
    • Lim, S.-H., Hudson, S.M., 2004. Synthesis and antimicrobial activity of a water-soluble chitosan derivative with a fiber-reactive group. Carbohydr. Res. 339, 313-319. (Pubitemid 38041136)
    • (2004) Carbohydrate Research , vol.339 , Issue.2 , pp. 313-319
    • Lim, S.-H.1    Hudson, S.M.2
  • 18
    • 59349093746 scopus 로고    scopus 로고
    • Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells
    • Liu, H.T., Li, W.M., Xu, G., Li, X.Y., Bai, X.F., Wei, P., Yu, C., Du, Y.G., 2009a. Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells. Pharmacol. Res. 59, 167-175.
    • (2009) Pharmacol. Res. , vol.59 , pp. 167-175
    • Liu, H.T.1    Li, W.M.2    Xu, G.3    Li, X.Y.4    Bai, X.F.5    Wei, P.6    Yu, C.7    Du, Y.G.8
  • 19
    • 67349241425 scopus 로고    scopus 로고
    • The preventive effects of heparin-superoxide dismutase on carbon tetrachloride-induced acute liver failure and hepatic fibrosis in mice
    • Liu, J.F., Tan, H.N., Sun, Y.F., Zhou, S., Cao, J.C., Wang, F.S., 2009b. The preventive effects of heparin-superoxide dismutase on carbon tetrachloride-induced acute liver failure and hepatic fibrosis in mice. Mol. Cell Biochem. 327, 219-228.
    • (2009) Mol. Cell Biochem. , vol.327 , pp. 219-228
    • Liu, J.F.1    Tan, H.N.2    Sun, Y.F.3    Zhou, S.4    Cao, J.C.5    Wang, F.S.6
  • 21
    • 70349895890 scopus 로고    scopus 로고
    • Invertible amphiphilic molecular pockets made of cholic acid
    • Luo, J.T., Chen, Y.L., Zhu, X.X., 2009. Invertible amphiphilic molecular pockets made of cholic acid. Langmuir 25, 10913-10917.
    • (2009) Langmuir , vol.25 , pp. 10913-10917
    • Luo, J.T.1    Chen, Y.L.2    Zhu, X.X.3
  • 22
    • 0016272750 scopus 로고
    • Involvement of superoxide anion radical in autoxidation of pyrogallol and a convenient assay for superoxide-dismutase
    • Marklund, S., Marklund, G., 1974. Involvement of superoxide anion radical in autoxidation of pyrogallol and a convenient assay for superoxide-dismutase. Eur. J. Biochem. 47, 469-474.
    • (1974) Eur. J. Biochem. , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 23
    • 18044363639 scopus 로고    scopus 로고
    • SOD, oxidative stress and human pathologies: A brief history and a future vision
    • DOI 10.1016/j.biopha.2005.03.005
    • Mccord, J.M., Edeas, M.A., 2005. SOD, oxidative stress and human pathologies: a brief history and a future vision. Biomed. Pharmacother. 59, 139-142. (Pubitemid 40603324)
    • (2005) Biomedicine and Pharmacotherapy , vol.59 , Issue.4 , pp. 139-142
    • McCord, J.M.1    Edeas, M.A.2
  • 24
    • 0016751633 scopus 로고
    • Free radicals and inflammation
    • Mccord, J.M., Salin, M.L., 1975. Free radicals and inflammation. J. Clin. Invest. 56, 1319-1323.
    • (1975) J. Clin. Invest. , vol.56 , pp. 1319-1323
    • Mccord, J.M.1    Salin, M.L.2
  • 25
    • 22644439708 scopus 로고    scopus 로고
    • Chemistry and biology of bile acids
    • Mukhopadhyay, S., Maitra, U., 2004. Chemistry and biology of bile acids. Curr. Sci. 87, 1666-1683. (Pubitemid 41024553)
    • (2004) Current Science , vol.87 , Issue.12 , pp. 1666-1683
    • Mukhopadhyay, S.1    Maitra, U.2
  • 27
    • 0023818970 scopus 로고
    • 125I-labelled bovine superoxide dismutase (SOD) in the rat
    • Odlind, B., Appelgren, L.-E., Bayati, A., Wolgast, M., 1988. Tissue distribution of i-125-labeled bovine superoxide-dismutase (SOD) in the rat. Pharmacol. Toxicol. 62, 95-100. (Pubitemid 18049719)
    • (1988) Pharmacology and Toxicology , vol.62 , Issue.2 , pp. 95-100
    • Odlind, B.1    Appelgren, L.-E.2    Bayati, A.3    Wolgast, M.4
  • 28
    • 77949855159 scopus 로고    scopus 로고
    • Quantitative analysis and simultaneous activity measurements of Cu,Zn-superoxide dismutase in red blood cells by HPLC-ICPMS
    • Ordonez, Y.N., Montes-Bayon, M., Blanco-Gonzalez, E., Sanz-Medel, A., 2010. Quantitative analysis and simultaneous activity measurements of Cu,Zn-superoxide dismutase in red blood cells by HPLC-ICPMS. Anal. Chem. 82, 2387-2394.
    • (2010) Anal. Chem. , vol.82 , pp. 2387-2394
    • Ordonez, Y.N.1    Montes-Bayon, M.2    Blanco-Gonzalez, E.3    Sanz-Medel, A.4
  • 29
    • 33745600868 scopus 로고    scopus 로고
    • Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective
    • DOI 10.1016/j.jconrel.2006.04.015, PII S0168365906002057
    • Ratnam, D.V., Ankola, D.D., Bhardwaj, V., Sahana, D.K., Kumar, M.N.V.R., 2006. Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective. J. Control. Release 113, 189-207. (Pubitemid 43983041)
    • (2006) Journal of Controlled Release , vol.113 , Issue.3 , pp. 189-207
    • Ratnam, D.V.1    Ankola, D.D.2    Bhardwaj, V.3    Sahana, D.K.4    Kumar, M.N.V.R.5
  • 30
    • 0029055175 scopus 로고
    • Oxidative processes and antioxidative defense mechanisms in the aging brain
    • Reiter, R.J., 1995. Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J. 9, 526-533.
    • (1995) FASEB J. , vol.9 , pp. 526-533
    • Reiter, R.J.1
  • 32
    • 72149126107 scopus 로고    scopus 로고
    • The delivery of superoxide dismutase encapsulated in polyketal microparticles to rat myocardium and protection from myocardial ischemia-reperfusion injury
    • Seshadri, G., Sy, J.C., Brown, M., Dikalov, S., Yang, S.C., Murthy, N., Davis, M.E., 2010. The delivery of superoxide dismutase encapsulated in polyketal microparticles to rat myocardium and protection from myocardial ischemia-reperfusion injury. Biomaterials 31, 1372-1379.
    • (2010) Biomaterials , vol.31 , pp. 1372-1379
    • Seshadri, G.1    Sy, J.C.2    Brown, M.3    Dikalov, S.4    Yang, S.C.5    Murthy, N.6    Davis, M.E.7
  • 33
    • 14844292727 scopus 로고    scopus 로고
    • Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by SOD in Transfersomes
    • DOI 10.1016/j.jconrel.2004.12.008, PII S0168365904006303
    • Simoes, S.I., Delgado, T.C., Lopes, R.M., Jesus, S., Ferreira, A.A., Morais, J.A., Cruz, M.E.M., Corvo, M.L., Martins, M.B.F., 2005. Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by SOD in transfersomes. J. Control. Release 103, 419-434. (Pubitemid 40342539)
    • (2005) Journal of Controlled Release , vol.103 , Issue.2 , pp. 419-434
    • Simoes, S.I.1    Delgado, T.C.2    Lopes, R.M.3    Jesus, S.4    Ferreira, A.A.5    Morais, J.A.6    Cruz, M.E.M.7    Corvo, M.L.8    Martins, M.B.F.9
  • 34
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid
    • DOI 10.1016/0003-2697(85)90442-7
    • Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J., Klenk, D.C., 1985. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85. (Pubitemid 16258399)
    • (1985) Analytical Biochemistry , vol.150 , Issue.1 , pp. 76-85
    • Smith, P.K.1    Krohn, R.I.2    Hermanson, G.T.3
  • 35
    • 76749103819 scopus 로고    scopus 로고
    • Enteric-coated capsules filled with freeze-dried chitosan/poly(gamma- glutamic acid) nanoparticles for oral insulin delivery
    • Sonaje, K., Chen, Y.-J., Chen, H.-L., Wey, S.-P., Juang, J.-H., Nguyen, H.-N., Hsu, C.-W., Lin, K.-J., Sung, H.-W., 2010. Enteric-coated capsules filled with freeze-dried chitosan/poly(gamma-glutamic acid) nanoparticles for oral insulin delivery. Biomaterials 31, 3384-3394.
    • (2010) Biomaterials , vol.31 , pp. 3384-3394
    • Sonaje, K.1    Chen, Y.-J.2    Chen, H.-L.3    Wey, S.-P.4    Juang, J.-H.5    Nguyen, H.-N.6    Hsu, C.-W.7    Lin, K.-J.8    Sung, H.-W.9
  • 36
    • 78951478230 scopus 로고    scopus 로고
    • In vitro evaluation of N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan for oral insulin delivery
    • Sonia, T.A., Sharma, C.P., 2011. In vitro evaluation of N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan for oral insulin delivery. Carbohydr. Polym. 84, 103-109.
    • (2011) Carbohydr. Polym. , vol.84 , pp. 103-109
    • Sonia, T.A.1    Sharma, C.P.2
  • 37
    • 34250195000 scopus 로고    scopus 로고
    • Preparation of nanoparticles composed of chitosan and its derivatives as delivery systems for macromolecules
    • DOI 10.1002/app.26038
    • Sun, Y., Wan, A., 2007. Preparation of nanoparticles composed of chitosan and its derivatives as delivery systems for macromolecules. J. Appl. Polym. Sci. 105, 552-561. (Pubitemid 46896620)
    • (2007) Journal of Applied Polymer Science , vol.105 , Issue.2 , pp. 552-561
    • Sun, Y.1    Wan, A.2
  • 38
    • 0023952554 scopus 로고
    • A simple method for clinical assay of superoxide dismutase
    • Sun, Y., Oberlery, L.W., Li, Y., 1988. A simple method for clinical assay of superoxide dismutase. Clin. Chem. 34, 497-500.
    • (1988) Clin. Chem. , vol.34 , pp. 497-500
    • Sun, Y.1    Oberlery, L.W.2    Li, Y.3
  • 39
    • 9644266754 scopus 로고    scopus 로고
    • Superoxide anion scavenging activity of graft chitosan derivatives
    • Sun, T., Xie, W.M., Xu, P.X., 2004. Superoxide anion scavenging activity of graft chitosan derivatives. Carbohydr. Polym. 58, 379-382.
    • (2004) Carbohydr. Polym. , vol.58 , pp. 379-382
    • Sun, T.1    Xie, W.M.2    Xu, P.X.3
  • 40
    • 72749093756 scopus 로고    scopus 로고
    • Recent developments in liposomes, microparticles and nanoparticles for protein and peptide drug delivery
    • Tan, M.L., Choong, P.F.M., Dass, C.R., 2010. Recent developments in liposomes, microparticles and nanoparticles for protein and peptide drug delivery. Peptides 31, 184-193.
    • (2010) Peptides , vol.31 , pp. 184-193
    • Tan, M.L.1    Choong, P.F.M.2    Dass, C.R.3
  • 41
    • 64849101493 scopus 로고    scopus 로고
    • Protein dynamism and evolvability
    • Tokuriki, N., Tawfik, D.S., 2009. Protein dynamism and evolvability. Science 324, 203-207.
    • (2009) Science , vol.324 , pp. 203-207
    • Tokuriki, N.1    Tawfik, D.S.2
  • 42
    • 33750911068 scopus 로고    scopus 로고
    • The activities of antioxidant enzymes and the level of malondialdehyde in cerebellum of rats subjected to methotrexate: Protective effect of caffeic acid phenethyl ester
    • DOI 10.1007/s11010-006-9196-5
    • Uzar, E., Koyuncuoglu, H.R., Uz, E., Yilmaz, H.R., Kutluhan, S., Kilbas, S., Gultekin, F., 2006. The activities of antioxidant enzymes and the level of malondialdehyde in cerebellum of rats subjected to methotrexate: protective effect of caffeic acid phenethyl ester. Mol. Cell Biochem. 291, 63-68. (Pubitemid 44725303)
    • (2006) Molecular and Cellular Biochemistry , vol.291 , Issue.1-2 , pp. 63-68
    • Uzar, E.1    Koyuncuoglu, H.R.2    Uz, E.3    Yilmaz, H.R.4    Kutluhan, S.5    Kilbas, S.6    Gultekin, F.7
  • 44
    • 0037124547 scopus 로고    scopus 로고
    • Polyethylene glycol-superoxide dismutase, a conjugate in search of exploitation
    • DOI 10.1016/S0169-409X(02)00029-7, PII S0169409X02000297
    • Veronese, F.M., Caliceti, P., Schiavon, O., Sergi, M., 2002. Polyethylene glycolsuperoxide dismutase, a conjugate in search of exploitation. Adv. Drug Deliv. Rev. 54, 587-606. (Pubitemid 34615549)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.4 , pp. 587-606
    • Veronese, F.M.1    Caliceti, P.2    Schiavon, O.3    Sergi, M.4
  • 45
    • 33646356983 scopus 로고    scopus 로고
    • A thermo- and pH-sensitive hydrogel composed of quaternized chitosan/glycerophosphate
    • DOI 10.1016/j.ijpharm.2006.01.045, PII S0378517306000809
    • Wu, J., Su, Z.G., Ma, G.H., 2006. A thermo- and pH-sensitive hydrogel composed of quaternized chitosan/glycerophosphate. Int. J. Pharm. 315, 1-11. (Pubitemid 43674112)
    • (2006) International Journal of Pharmaceutics , vol.315 , Issue.1-2 , pp. 1-11
    • Wu, J.1    Su, Z.-G.2    Ma, G.-H.3
  • 46
    • 84855196469 scopus 로고    scopus 로고
    • Synthesis and characterization of N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride for potential application in gene delivery
    • Xiao, B., Wan, Y., Wang, X.Y., Zha, Q.C., Liu, H.M., Qiu, Z.Y., Zhang, S.M., 2012. Synthesis and characterization of N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride for potential application in gene delivery. Colloids Surf. B 91, 168-174.
    • (2012) Colloids Surf. B , vol.91 , pp. 168-174
    • Xiao, B.1    Wan, Y.2    Wang, X.Y.3    Zha, Q.C.4    Liu, H.M.5    Qiu, Z.Y.6    Zhang, S.M.7
  • 47
    • 84859710349 scopus 로고    scopus 로고
    • Amphiphilic cholic-acid-modified dextran sulfate and its application for the controlled delivery of superoxide dismutase
    • Xiong, Y.B., Qi, J.N., Yao, P., 2012. Amphiphilic cholic-acid-modified dextran sulfate and its application for the controlled delivery of superoxide dismutase. Macromol. Biosci. 12, 515-524.
    • (2012) Macromol. Biosci. , vol.12 , pp. 515-524
    • Xiong, Y.B.1    Qi, J.N.2    Yao, P.3
  • 48
    • 0141961727 scopus 로고    scopus 로고
    • Preparation and modification of N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride nanoparticle as a protein carrier
    • Xu, Y.M., Du, Y.M., Huang, R.H., Gao, L.P., 2003. Preparation and modification of N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride nanoparticle as a protein carrier. Biomaterials 24, 5015-5022.
    • (2003) Biomaterials , vol.24 , pp. 5015-5022
    • Xu, Y.M.1    Du, Y.M.2    Huang, R.H.3    Gao, L.P.4
  • 49
    • 84861092442 scopus 로고    scopus 로고
    • Synthesis and characteristics of chitin and chitosan with the (2-hydroxy-3-trimethylammonium)propyl functionality, and evaluation of their antioxidant activity in vitro
    • Zhang, X., Geng, X.D., Jiang, H.J., Li, J.R., Huang, J.Y., 2012. Synthesis and characteristics of chitin and chitosan with the (2-hydroxy-3-trimethylammonium)propyl functionality, and evaluation of their antioxidant activity in vitro. Carbohydr. Polym. 89, 486-491.
    • (2012) Carbohydr. Polym. , vol.89 , pp. 486-491
    • Zhang, X.1    Geng, X.D.2    Jiang, H.J.3    Li, J.R.4    Huang, J.Y.5
  • 50
    • 77953363802 scopus 로고    scopus 로고
    • N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride nanoparticle as a novel delivery system for Parathyroid Hormone-Related Protein 1-34
    • Zhao, S.-H., Wu, X.-T., Guo, W.-C., Du, Y.-M., Yu, L., Tang, J., 2010. N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride nanoparticle as a novel delivery system for Parathyroid Hormone-Related Protein 1-34. Int. J. Pharm. 393, 268-272.
    • (2010) Int. J. Pharm. , vol.393 , pp. 268-272
    • Zhao, S.-H.1    Wu, X.-T.2    Guo, W.-C.3    Du, Y.-M.4    Yu, L.5    Tang, J.6
  • 51
    • 78650294585 scopus 로고    scopus 로고
    • Synthesis and characterization of amphiphilic glycidol-chitosan- deoxycholic acid nanoparticles as a drug carrier for doxorubicin
    • Zhou, H.F., Yu, W.T., Guo, X., Liu, X.D., Li, N., Zhang, Y., Ma, X.J., 2010. Synthesis and characterization of amphiphilic glycidol-chitosan- deoxycholic acid nanoparticles as a drug carrier for doxorubicin. Biomacromolecules 11, 3480-3486.
    • (2010) Biomacromolecules , vol.11 , pp. 3480-3486
    • Zhou, H.F.1    Yu, W.T.2    Guo, X.3    Liu, X.D.4    Li, N.5    Zhang, Y.6    Ma, X.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.