Gene-Environment Interactions: Eco-Genetics and Toxicogenomics

Genomic and Personalized Medicine

Volumn 1, Issue , 2013, Pages 50-59

  Omenn, Gilbert S ^a  

^a Center for Computational Medicine and Bioinformatics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84884095940     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-382227-7.00004-5     Document Type: Chapter

References (55)

1. Andersen J.B., Factor V.M., Marquardt J.U., et al. An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer. Sci Transl Med 2010, (2):54ra77.
2. Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue
3. Belinsky S.A., Liechty K.C., Gentry F.D., et al. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res 2006, 66:3338-3344.
4. Brewer G.J. Annotation: Human ecology, an expanding role for the human geneticist. Am J Hum Genet 1971, 23:92-94.
5. Bushel P.R., Heinloth A.N., Li J., et al. Blood gene expression signatures predict exposure levels. Proc Natl Acad Sci USA 2007, 104:18,211-18,216.
6. Cantonwine D., Hu H., Tellez-Rojo M.M., et al. HFE gene variants modify the association between maternal lead burden and infant birthweight: A prospective birth cohort study in Mexico city, Mexico. Environ Health 2010, 9:43.
7. Cecil J.E., Tavendale R., Watt P., Hetherington M.M., Palmer C.N.A. An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med 2008, 359:2558-2566.
8. Collins F.S. The case for a US prospective cohort study of genes and environment. Nature 2004, 429:475-477.
9. Cordain L., Eaton S.B., Sebastian A., et al. Origins and evolution of the Western diet: Health implications for the 21st century. Am J Clin Nutr 2005, 81:341-354.
10. Cosio B.G., Mann B., Ito K., et al. Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma. Am J Respir Crit Care Med 2004, 170:141-147.
11. Gene-Environment Interactions: Fundamentals of Eco-Genetics 2006, Wiley, New York. L.G. Costa, D.E. Eaton (Eds.).
12. Costa L.G., Furlong C.E. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects 2002, Kluwer Academic Publishers, Boston.
13. Daston G.P., Naciff J.M. Predicting developmental toxicity through toxicogenomics. Birth Defects Res C: Embryo Today: Reviews 2010, 90:110-117.
14. Davis A.P., King B.L., Mockus S., et al. The comparative toxicogenomics database: Update 2011. Nucleic Acids Res 2011, 39:D1067-D1072.
15. Dean M., Carrington M., Winkler C., et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia growth and development study, multicenter AIDS cohort study, Multicenter hemophilia cohort study, San Francisco city Cohort, ALIVE study. Science 1996, 273:1856-1862.
16. Digel W., Lubbert M. DNA methylation disturbances as novel therapeutic target in lung cancer: Preclinical and clinical results. Crit Rev Oncol Hematol 2005, 55:1-11.
17. Durbin R.M., Abecasis G.R., Altshuler D.L., et al. 1000 Genomes Project Consortium: A map of human genome variation from population-scale sequencing. Nature 2010, 467:1061-1073.
18. Ege M.J., Herzum I., Buchele G., et al. Prenatal exposure to a farm environment modifies atopic sensitization at birth. J Allergy Clin Immunol 2008, 122:407-412.
19. EPA Potential Implications of Genomics for Regulatory and Risk Assessment Applications at EPA 2004, Genomics Task Force Workgroup, EPA Science Policy Council, Washington, DC.
20. Garantziotis S., Schwartz D.A. Ecogenomics of respiratory diseases of public health significance. Annu Rev Public Health 2010, 31:37-51.
21. Garcia-Closas M., Thompson W.D., Robins J.M. Differential misclassification and the assessment of gene-environment interactions in case-control studies. Am J Epidemiol 1998, 147:426-433.
22. Garrod A.E. About alkaptonuria. Med Chir Trans 1902, 85:69-78.
23. Gilliland F.D., Li Y.F., Saxon A., Diaz-Sanchez D. Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: Randomised, placebo-controlled crossover study. Lancet 2004, 363:119-125.
24. Haberg S.E., London S.J., Stigum H., Nafstad P., Nystad W. Folic acid supplements in pregnancy and early childhood respiratory health. Arch Dis Child 2009, 94:180-184.
25. Halfmann R., Lindquist S. Epigenetics in the extreme: Prions and the inheritance of environmentally acquired traits. Science 2010, 330:629-632.
26. Hansen N.T., Brunak S., Altman R.B. Generating genome-scale candidate gene lists for pharmacogenomics. Clin Pharmacol Ther 2009, 86:183-189.
27. Harrill A.H., Ross P.K., Gatti D.M., Threadgill D.W., Rusyn I. Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. Toxicol Sci 2009, 110:235-243.
28. Hollingsworth J.W., Maruoka S., Boon K., et al. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest 2008, 118:3462-3469.
29. IOM, Institute of Medicine Committee on Omics-Based Predictive tests, 2012. Evaluation of Traditional Omics, eds. Micahel, C.C., Nass, S., Omenn, G.S. National Academy Press, Washington, D.C.
30. Ito K., Ito M., Elliott W.M., et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 2005, 352:1967-1976.
31. Kraft P., Hunter D. Integrating epidemiology and genetic association: The challenge of gene-environment interaction. Philos Trans R Soc Lond B 2005, 360:1609-1616.
32. Kramer C.B., Cullen A.C., Faustman E.M. Policy implications of genetic information on regulation under the Clean Air Act: The case of particulate matter and asthmatics. Environ Health Perspect 2006, 114:313-319.
33. Le Marchand L., Hankin J.H., Wilkens L.R., et al. Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 2001, 10:1259-1266.
34. McBride C.M., Koehly L.M., Sanderson S.C., Kaphingst K.A. The behavioral response to personalized genetic information: Will genetic risk profiles motivate individuals and families to choose more healthful behaviors?. Annu Rev Public Health 2010, 31:89-103.
35. McNicholl J.M., Downer M.V., Udhayakumar V., Alper C.A., Swerdlow D.L. Host-pathogen interactions in emerging and re-emerging infectious diseases: A genomic perspective of tuberculosis, malaria, human immunodeficiency virus infection, hepatitis B, and cholera. Annu Rev Public Health 2000, 21:15-46.
36. Olden K. Human health and disease: Interaction between the genome and the environment. Genomic and Personalized Medicine 2009, Elsevier, Burlington. H.F. Willard, G.S. Ginsburg (Eds.).
37. Omenn G.S. From human genome research to personalized health care. Issues Sci Technol 2009, 51-56. Summer.
38. Omenn G.S. Overview of the symposium on public health significance of genomics and eco-genetics. Annu Rev Public Health 2010, 31:1-8.
39. Omenn G.S. Evolution in health and medicine Sackler colloquium: Evolution and public health. Proc Natl Acad Sci USA 2010, 107(Suppl. 1):1702-1709.
40. Omenn G.S., Motulsky A.G. Eco-genetics: Genetic variation in susceptibility to environmental agents. Genetic Isssues in Public Health and Medicine 1978, CC Thomas, Springfield, IL. B.H. Cohen, A.M. Lilienfeld, P.C. Huang (Eds.).
41. Ramos R.G., Olden K. Gene-environment interactions in the development of complex disease phenotypes. Int J Environ Res Public Health 2008, 5:4-11.
42. Schwartz D.A. Epigenetics and environmental lung disease. Proc Am Thorac Soc 2010, 7:123-125.
43. Simopoulos A.P. Nutrigenetics/nutrigenomics. Annu Rev Public Health 2010, 31:53-68.
44. Smith M.W., Dean M., Carrington M., et al. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia growth and development study (HGDS), Multicenter aids cohort study (MACS), Multicenter hemophilia cohort study (MHCS), San Francisco city cohort (SFCC), ALIVE study. Science 1997, 277:959-965.
45. Thomas D. Gene-environment-wide association studies: Emerging approaches. Nat Rev Genet 2010, 11:259-272.
46. Thomas D. Methods for investigating gene-environment interactions in candidate pathway and genome-wide association studies. Annu Rev Public Health 2010, 31:21-36.
47. Thomas D.C. Viewpoint: Using gene-environment interactions to dissect the effects of complex mixtures. J Expo Sci Environ Epidemiol 2007, 17(Suppl. 2):S71-S74.
48. Vesell E.S. Genetic and environmental factors causing variation in drug response. Mutat Res 1991, 247:241-257.
49. Vogel F., Motulsky A.G. Human evolution. Human Genetics: Problems and Approaches 1997, Springer-Verlag, Berlin. third ed. F. Vogel, A.G. Motulsky (Eds.).
50. Wang F.T., Hu H., Schwartz J., et al. Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive decline. Environ Health Perspect 2007, 115:1210-1215.
51. Waterland R.A., Jirtle R.L. Transposable elements: Targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 2003, 23:5293-5300.
52. Waters M., Stasiewicz S., Alex Merrick B., et al. CEBS - chemical effects in biological systems: A public data repository integrating study design and toxicity data with microarray and proteomics data. Nucleic Acids Res 2008, 36:D892-D900.
53. Weis B.K., Balshaw D., Barr J.R., et al. Personalized exposure assessment: Promising approaches for human environmental health research. Environ Health Perspect 2005, 113:840-848.
54. Wu M.T., Kelsey K., Schwartz J., et al. A delta-aminolevulinic acid dehydratase (ALAD) polymorphism may modify the relationship of low-level lead exposure to uricemia and renal function: The normative aging study. Environ Health Perspect 2003, 111:335-341.
55. Yang Q., Khoury M.J. Evolving methods in genetic epidemiology. III. Gene-environment interaction in epidemiologic research. Epidemiol Rev 1997, 19:33-43.