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Volumn 5, Issue 1, 2008, Pages 4-11

Gene-environment interactions in the development of complex disease phenotypes

Author keywords

Disease; Environment; Exposure; Genes; Phenotype

Indexed keywords

AUTOIMMUNE DISEASE; BERYLLIOSIS; CHRONIC DISEASE; ENVIRONMENTAL DISEASE; ENVIRONMENTAL EXPOSURE; GENOTYPE ENVIRONMENT INTERACTION; HEALTH CARE POLICY; HEALTH HAZARD; HEREDITY; HIGH RISK POPULATION; HUMAN; MEDICAL RESEARCH; OCCUPATIONAL DISEASE; OCCUPATIONAL EXPOSURE; OCCUPATIONAL SAFETY; PARKINSON DISEASE; PHENOTYPE; POPULATION RESEARCH; REVIEW;

EID: 41649108879     PISSN: None     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph5010004     Document Type: Review
Times cited : (49)

References (72)
  • 1
    • 50749093820 scopus 로고    scopus 로고
    • Garrod, A..: The incidence of alkatonuria: a study in chemical individuality. Lancet, 1902, 160(4137): p. 1616-1620.
    • Garrod, A..: The incidence of alkatonuria: a study in chemical individuality. Lancet, 1902, 160(4137): p. 1616-1620.
  • 2
    • 0000907353 scopus 로고
    • The roles of nutrition, inbreeding, crossbreeding, and selection in evolution
    • Wright, S.: The roles of nutrition, inbreeding, crossbreeding, and selection in evolution. Proceedings of the Sixth Annual Congress of Genetics, 1932: p. 356-366.
    • (1932) Proceedings of the Sixth Annual Congress of Genetics , pp. 356-366
    • Wright, S.1
  • 3
    • 0027922204 scopus 로고
    • Opportunities in environmental health science research
    • Olden, K.: Opportunities in environmental health science research. Environ Health Perspect, 1993, 101(1): p. 6-7.
    • (1993) Environ Health Perspect , vol.101 , Issue.1 , pp. 6-7
    • Olden, K.1
  • 4
    • 0035945703 scopus 로고    scopus 로고
    • Genomics: Implications for toxicology
    • Olden, K.; Guthrie, J.: Genomics: implications for toxicology. Mutat Res, 2001, 473(1): p. 3-10.
    • (2001) Mutat Res , vol.473 , Issue.1 , pp. 3-10
    • Olden, K.1    Guthrie, J.2
  • 5
    • 0035193380 scopus 로고    scopus 로고
    • A bold new direction for environmental health research
    • Olden, K.; Guthrie, J.; Newton, S.: A bold new direction for environmental health research. Am J Public Health, 2001, 91(12): p. 1964-7.
    • (2001) Am J Public Health , vol.91 , Issue.12 , pp. 1964-1967
    • Olden, K.1    Guthrie, J.2    Newton, S.3
  • 6
    • 0031990657 scopus 로고    scopus 로고
    • Genomics and human disease - variations on variation
    • Brown, P. O.; Hartwell, L.: Genomics and human disease - variations on variation. Nat Genet, 1998, 18(2): p. 91-3.
    • (1998) Nat Genet , vol.18 , Issue.2 , pp. 91-93
    • Brown, P.O.1    Hartwell, L.2
  • 7
    • 0031726283 scopus 로고    scopus 로고
    • The Environmental Genome Project: Functional analysis of polymorphisms
    • Guengerich, F. P.: The Environmental Genome Project: functional analysis of polymorphisms. Environ Health Perspect, 1998, 106(7): p. 365-8.
    • (1998) Environ Health Perspect , vol.106 , Issue.7 , pp. 365-368
    • Guengerich, F.P.1
  • 8
    • 0030714011 scopus 로고    scopus 로고
    • Environment institute lays plans for gene hunt
    • Kaiser, J.: Environment institute lays plans for gene hunt. Science, 1997, 278(5338): p. 569-70.
    • (1997) Science , vol.278 , Issue.5338 , pp. 569-570
    • Kaiser, J.1
  • 9
    • 0034330533 scopus 로고    scopus 로고
    • Environmental health and genomics: Visions and implications
    • Olden, K.; Wilson, S.: Environmental health and genomics: visions and implications. Nat Rev Genet, 2000, 1(2): p. 149-53.
    • (2000) Nat Rev Genet , vol.1 , Issue.2 , pp. 149-153
    • Olden, K.1    Wilson, S.2
  • 10
    • 0032906829 scopus 로고    scopus 로고
    • Hulla, J. E., et al.: Symposium overview: the role of genetic polymorphism and repair deficiencies in environmental disease. Toxicol Sci, 1999, 47(2): p. 135-43.
    • Hulla, J. E., et al.: Symposium overview: the role of genetic polymorphism and repair deficiencies in environmental disease. Toxicol Sci, 1999, 47(2): p. 135-43.
  • 11
    • 0029963622 scopus 로고    scopus 로고
    • Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer
    • Nebert, D. W.; McKinnon, R. A.; Puga, A.: Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer. DNA Cell Biol, 1996, 15(4): p. 273-80.
    • (1996) DNA Cell Biol , vol.15 , Issue.4 , pp. 273-280
    • Nebert, D.W.1    McKinnon, R.A.2    Puga, A.3
  • 12
    • 34248532571 scopus 로고    scopus 로고
    • Traffic and outdoor air pollution levels near residences and poorly controlled asthma in adults
    • Meng, Y. Y., et al.: Traffic and outdoor air pollution levels near residences and poorly controlled asthma in adults. Ann Allergy Asthma Immunol, 2007, 98(5): p. 455-63.
    • (2007) Ann Allergy Asthma Immunol , vol.98 , Issue.5 , pp. 455-463
    • Meng, Y.Y.1
  • 13
    • 34147108294 scopus 로고    scopus 로고
    • Local genetic and environmental factors in asthma disease pathogenesis: Chronicity and persistence mechanisms
    • Holgate, S. T., et al,: Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms. Eur Respir J, 2007, 29(4): p. 793-803.
    • (2007) Eur Respir J , vol.29 , Issue.4 , pp. 793-803
    • Holgate, S.T.1
  • 14
    • 33947186672 scopus 로고    scopus 로고
    • The urban built environment and obesity in New York City: A multilevel analysis
    • Rundle, A., et al.: The urban built environment and obesity in New York City: a multilevel analysis. Am J Health Promot, 2007, 21(4 Suppl): p. 326-34.
    • (2007) Am J Health Promot , vol.21 , Issue.4 SUPPL. , pp. 326-334
    • Rundle, A.1
  • 15
    • 33745615130 scopus 로고    scopus 로고
    • Built and social environments associations with adolescent overweight and activity
    • Nelson, M. C., et al.: Built and social environments associations with adolescent overweight and activity. Am J Prev Med, 2006, 31(2): p. 109-17.
    • (2006) Am J Prev Med , vol.31 , Issue.2 , pp. 109-117
    • Nelson, M.C.1
  • 16
    • 34548843150 scopus 로고    scopus 로고
    • Air pollution and inflammatory response in myocardial infarction survivors: Gene-environment interactions in a high-risk group
    • Peters, A., et al.: Air pollution and inflammatory response in myocardial infarction survivors: gene-environment interactions in a high-risk group. Inhal Toxicol, 2007, 19 Suppl 1: p. 161-75.
    • (2007) Inhal Toxicol , vol.19 , Issue.SUPPL. 1 , pp. 161-175
    • Peters, A.1
  • 17
    • 34548201725 scopus 로고    scopus 로고
    • Geographic patterns in overall and specific cardiovascular disease incidence in apparently healthy men in the United States
    • Rich, D. Q.; Gaziano, J. M.; Kurth, T.: Geographic patterns in overall and specific cardiovascular disease incidence in apparently healthy men in the United States. Stroke, 2007, 38(8): p. 2221-7.
    • (2007) Stroke , vol.38 , Issue.8 , pp. 2221-2227
    • Rich, D.Q.1    Gaziano, J.M.2    Kurth, T.3
  • 18
    • 70349566593 scopus 로고
    • Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
    • Neel, J. V.: Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet, 1962, 14: p. 353-62.
    • (1962) Am J Hum Genet , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 19
    • 28144460075 scopus 로고    scopus 로고
    • Vertebrate-type intron-rich genes in the marine annelid Platynereis dumerilii
    • Raible, F., et al.: Vertebrate-type intron-rich genes in the marine annelid Platynereis dumerilii. Science, 2005, 310(5752): p. 1325-6.
    • (2005) Science , vol.310 , Issue.5752 , pp. 1325-1326
    • Raible, F.1
  • 20
    • 0034644185 scopus 로고    scopus 로고
    • Environmental and heritable factors in the causation of cancer -analyses of cohorts of twins from Sweden, Denmark, and Finland
    • Lichtenstein, P., et al.: Environmental and heritable factors in the causation of cancer -analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med, 2000, 343(2): p. 78-85.
    • (2000) N Engl J Med , vol.343 , Issue.2 , pp. 78-85
    • Lichtenstein, P.1
  • 21
    • 0032730732 scopus 로고    scopus 로고
    • Genetic predisposition, environment and cancer incidence: A nationwide twin study in Finland, 1976-1995
    • Verkasalo, P. K., et al.: Genetic predisposition, environment and cancer incidence: a nationwide twin study in Finland, 1976-1995. Int J Cancer, 1999, 83(6): p. 743-9.
    • (1999) Int J Cancer , vol.83 , Issue.6 , pp. 743-749
    • Verkasalo, P.K.1
  • 22
    • 0033608187 scopus 로고    scopus 로고
    • Parkinson disease in twins: An etiologic study
    • Tanner, C. M., et al.: Parkinson disease in twins: an etiologic study. Jama, 1999, 281(4): p. 341-6.
    • (1999) Jama , vol.281 , Issue.4 , pp. 341-346
    • Tanner, C.M.1
  • 23
    • 12244262220 scopus 로고    scopus 로고
    • Family history assessment: Strategies for prevention of cardiovascular disease
    • Hunt, S. C.; Gwinn, M.; Adams, T. D.: Family history assessment: strategies for prevention of cardiovascular disease. Am J Prev Med, 2003, 24(2): p. 136-42.
    • (2003) Am J Prev Med , vol.24 , Issue.2 , pp. 136-142
    • Hunt, S.C.1    Gwinn, M.2    Adams, T.D.3
  • 24
    • 0042195833 scopus 로고    scopus 로고
    • Major risk factors as antecedents of fatal and nonfatal coronary heart disease events
    • Greenland, P., et al.: Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. Jama, 2003, 290(7): p. 891-7.
    • (2003) Jama , vol.290 , Issue.7 , pp. 891-897
    • Greenland, P.1
  • 25
    • 0029075924 scopus 로고
    • Genetic background and environment contribute synergistically to the onset of autoimmune diseases
    • Luppi, P., et al.: Genetic background and environment contribute synergistically to the onset of autoimmune diseases. J Mol Med, 1995, 73(8): p. 381-93.
    • (1995) J Mol Med , vol.73 , Issue.8 , pp. 381-393
    • Luppi, P.1
  • 26
    • 0036072178 scopus 로고    scopus 로고
    • Impact of genetic and non-genetic factors in type 1 diabetes
    • Hawa, M. I., et al.: Impact of genetic and non-genetic factors in type 1 diabetes. Am J Med Genet, 2002, 115(1): p. 8-17.
    • (2002) Am J Med Genet , vol.115 , Issue.1 , pp. 8-17
    • Hawa, M.I.1
  • 27
    • 31444451575 scopus 로고    scopus 로고
    • Environmental triggers and determinants of type 1 diabetes
    • Knip, M., et al.: Environmental triggers and determinants of type 1 diabetes. Diabetes, 2005, 54 Suppl 2: p. S125-36.
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 2
    • Knip, M.1
  • 28
    • 20544460101 scopus 로고    scopus 로고
    • HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms
    • Thorsby, E.; Lie, B. A.: HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms. Transpl Immunol, 2005, 14(3-4): p. 175-82.
    • (2005) Transpl Immunol , vol.14 , Issue.3-4 , pp. 175-182
    • Thorsby, E.1    Lie, B.A.2
  • 29
    • 34748826738 scopus 로고    scopus 로고
    • Environmental exposures and gene regulation in disease etiology
    • Edwards, T. M.; Myers, J. P.: Environmental exposures and gene regulation in disease etiology. Environ Health Perspect, 2007, 115(9): p. 1264-70.
    • (2007) Environ Health Perspect , vol.115 , Issue.9 , pp. 1264-1270
    • Edwards, T.M.1    Myers, J.P.2
  • 30
    • 0035951501 scopus 로고    scopus 로고
    • The use of common genetic polymorphisms to enhance the epidemiologic study of environmental carcinogens
    • Rothman, N., et al.: The use of common genetic polymorphisms to enhance the epidemiologic study of environmental carcinogens. Biochim Biophys Acta, 2001, 1471(2): p. C1-10.
    • (2001) Biochim Biophys Acta , vol.1471 , Issue.2
    • Rothman, N.1
  • 31
    • 1442302289 scopus 로고    scopus 로고
    • Some implications of genetic biomarkers in occupational epidemiology and practice
    • Schulte, P. A.: Some implications of genetic biomarkers in occupational epidemiology and practice. Scand J Work Environ Health, 2004, 30(1): p. 71-9.
    • (2004) Scand J Work Environ Health , vol.30 , Issue.1 , pp. 71-79
    • Schulte, P.A.1
  • 32
    • 35548972592 scopus 로고    scopus 로고
    • The contributions of genetics and genomics to occupational safety and health
    • Schulte, P. A.: The contributions of genetics and genomics to occupational safety and health. Occupational and Environmental Medicine, 2007, 64(11): p. 717-718.
    • (2007) Occupational and Environmental Medicine , vol.64 , Issue.11 , pp. 717-718
    • Schulte, P.A.1
  • 33
    • 41649098932 scopus 로고    scopus 로고
    • CDC National Office of Public Health Genomics, September, cited 2008 Jan 14, CDC Office activities, Available from
    • CDC National Office of Public Health Genomics. Public Health Genomics at CDC-Accomplishments and Priorities 2004. September 2007 [cited 2008 Jan 14]; CDC Office activities]. Available from: http://www.cdc.gov/ genomics/activities/ogdp/2004/niosh.htm.
    • (2007) Public Health Genomics at CDC-Accomplishments and Priorities 2004
  • 34
    • 0027998336 scopus 로고
    • Inherited glutathione-S-transferase deficiency is a risk factor for pulmonary asbestosis
    • Smith, C. M., et al.: Inherited glutathione-S-transferase deficiency is a risk factor for pulmonary asbestosis. Cancer Epidemiol Biomarkers Prev, 1994. 3(6): p471-7.
    • (1994) Cancer Epidemiol Biomarkers Prev , vol.3 , Issue.6 , pp. 471-477
    • Smith, C.M.1
  • 35
    • 34247544317 scopus 로고    scopus 로고
    • Polymorphisms of glutathione-S-transferase M1 and manganese superoxide dismutase are associated with the risk of malignant pleural mesothelioma
    • Landi, S., et al.: Polymorphisms of glutathione-S-transferase M1 and manganese superoxide dismutase are associated with the risk of malignant pleural mesothelioma. International Journal of Cancer, 2007. 120(12): p. 2739-2743.
    • (2007) International Journal of Cancer , vol.120 , Issue.12 , pp. 2739-2743
    • Landi, S.1
  • 36
    • 0842264614 scopus 로고    scopus 로고
    • Global use of asbestos and the incidence of mesothelioma
    • Tossavainen, A.: Global use of asbestos and the incidence of mesothelioma. Int J Occup Environ Health, 2004, 10(1): p. 22-5.
    • (2004) Int J Occup Environ Health , vol.10 , Issue.1 , pp. 22-25
    • Tossavainen, A.1
  • 37
    • 34547656272 scopus 로고    scopus 로고
    • Malignant mesothelioma: Global incidence and relationship with asbestos
    • Bianchi, C.; Bianchi, T.: Malignant mesothelioma: global incidence and relationship with asbestos. Ind Health, 2007, 45(3): p. 379-87.
    • (2007) Ind Health , vol.45 , Issue.3 , pp. 379-387
    • Bianchi, C.1    Bianchi, T.2
  • 38
    • 33847685702 scopus 로고    scopus 로고
    • Ecological association between asbestos-related diseases and historical asbestos consumption: An international analysis
    • Lin, R. T., et al.: Ecological association between asbestos-related diseases and historical asbestos consumption: an international analysis. Lancet, 2007. 369(9564): p. 844-9.
    • (2007) Lancet , vol.369 , Issue.9564 , pp. 844-849
    • Lin, R.T.1
  • 39
    • 0032437916 scopus 로고    scopus 로고
    • Immunogenetic basis of environmental lung disease: Lessons from the berylliosis model
    • Saltini, C., et al.: Immunogenetic basis of environmental lung disease: lessons from the berylliosis model. European Respiratory Journal, 1998, 12(6): p. 1463-1475.
    • (1998) European Respiratory Journal , vol.12 , Issue.6 , pp. 1463-1475
    • Saltini, C.1
  • 40
    • 41649090653 scopus 로고    scopus 로고
    • cited 2008 Feb 14, Available from
    • Agency for Toxic Substances and Disease Registry. Tox FAQ's for Beryllium. 2002 [cited 2008 Feb 14]; Available from: http://www.atsdr.cdc.gov/tfacts4.html #bookmark04.
    • (2002) Tox FAQ's for Beryllium
  • 41
    • 19544381713 scopus 로고    scopus 로고
    • Beryllium workers' health risks
    • Newman, L. S., et al.: Beryllium workers' health risks. J Occup Environ Hyg, 2005, 2(6): p. D48-50.
    • (2005) J Occup Environ Hyg , vol.2 , Issue.6
    • Newman, L.S.1
  • 42
    • 6344240734 scopus 로고    scopus 로고
    • Industries in the United States with airborne beryllium exposure and estimates of the number of current workers potentially exposed
    • Henneberger, P. K., et al.: Industries in the United States with airborne beryllium exposure and estimates of the number of current workers potentially exposed. J Occup Environ Hyg, 2004, 1(10): p. 648-59.
    • (2004) J Occup Environ Hyg , vol.1 , Issue.10 , pp. 648-659
    • Henneberger, P.K.1
  • 43
    • 32644434428 scopus 로고    scopus 로고
    • Sensitization and chronic beryllium disease among workers in copper-beryllium distribution centers
    • Stanton, M. L., et al.: Sensitization and chronic beryllium disease among workers in copper-beryllium distribution centers. J Occup Environ Med, 2006, 48(2): p. 204-11.
    • (2006) J Occup Environ Med , vol.48 , Issue.2 , pp. 204-211
    • Stanton, M.L.1
  • 44
    • 0029827342 scopus 로고    scopus 로고
    • The natural history of beryllium sensitization and chronic beryllium disease
    • Newman, L. S.; Lloyd, J.; Daniloff, E.: The natural history of beryllium sensitization and chronic beryllium disease. Environ Health Perspect, 1996. 104 Suppl 5: p. 937-43.
    • (1996) Environ Health Perspect , vol.104 , Issue.SUPPL. 5 , pp. 937-943
    • Newman, L.S.1    Lloyd, J.2    Daniloff, E.3
  • 45
    • 0024327288 scopus 로고
    • Pathologic and immunologic alterations in early stages of beryllium disease. Reexamination of disease definition and natural history
    • Newman, L. S., et al.: Pathologic and immunologic alterations in early stages of beryllium disease. Reexamination of disease definition and natural history. Am Rev Respir Dis, 1989, 139(6): p. 1479-86.
    • (1989) Am Rev Respir Dis , vol.139 , Issue.6 , pp. 1479-1486
    • Newman, L.S.1
  • 46
    • 24744445780 scopus 로고    scopus 로고
    • Genetic susceptibility and immune-mediated destruction in beryllium-induced disease
    • Fontenot, A. P.; Maier, L. A.: Genetic susceptibility and immune-mediated destruction in beryllium-induced disease. Trends in Immunology, 2005, 26(10): p. 543-549.
    • (2005) Trends in Immunology , vol.26 , Issue.10 , pp. 543-549
    • Fontenot, A.P.1    Maier, L.A.2
  • 47
    • 0027430877 scopus 로고
    • HLA-DPB1 glutamate 69: A genetic marker of beryllium disease
    • Richeldi, L.; Sorrentino, R.; Saltini, C.: HLA-DPB1 glutamate 69: a genetic marker of beryllium disease. Science, 1993, 262(5131): p. 242-4.
    • (1993) Science , vol.262 , Issue.5131 , pp. 242-244
    • Richeldi, L.1    Sorrentino, R.2    Saltini, C.3
  • 48
    • 0033178964 scopus 로고    scopus 로고
    • Differential susceptibilities to chronic beryllium disease contributed by different Glu69 HLA-DPB1 and -DPA1 alleles
    • Wang, Z., et al.: Differential susceptibilities to chronic beryllium disease contributed by different Glu69 HLA-DPB1 and -DPA1 alleles. J Immunol, 1999, 163(3): p. 1647-53.
    • (1999) J Immunol , vol.163 , Issue.3 , pp. 1647-1653
    • Wang, Z.1
  • 49
    • 41649114650 scopus 로고    scopus 로고
    • National Institute of Occupational Safety and Hazards. Worker Health Chartbook, 2004; Respiratory Diseases. 2004 [cited 2008 Feb 15]; NIOSH Publication No. 2004-146: Available from: http://www2a.cdc.gov/NIOSH- Chartbook/ch2/ch2-10-3.asp.
    • National Institute of Occupational Safety and Hazards. Worker Health Chartbook, 2004; Respiratory Diseases. 2004 [cited 2008 Feb 15]; NIOSH Publication No. 2004-146: Available from: http://www2a.cdc.gov/NIOSH- Chartbook/ch2/ch2-10-3.asp.
  • 50
    • 0035460783 scopus 로고    scopus 로고
    • Genotype and phenotype in susceptibility to coal workers' pneumoconiosis. The use of cytokines in perspective
    • Borm, P. J. A.; Schins, R. P. F.: Genotype and phenotype in susceptibility to coal workers' pneumoconiosis. The use of cytokines in perspective. European Respiratory Journal, 2001, 18(32 suppl): p. 127S-133.
    • (2001) European Respiratory Journal , vol.18 , Issue.32 SUPPL.
    • Borm, P.J.A.1    Schins, R.P.F.2
  • 51
    • 0035117949 scopus 로고    scopus 로고
    • Polymorphisms of the IL-1 gene complex in coal miners with silicosis
    • Yucesoy, B., et al.: Polymorphisms of the IL-1 gene complex in coal miners with silicosis. American Journal of Industrial Medicine, 2001, 39(3): p. 286-291.
    • (2001) American Journal of Industrial Medicine , vol.39 , Issue.3 , pp. 286-291
    • Yucesoy, B.1
  • 52
    • 0029966182 scopus 로고    scopus 로고
    • Transforming growth factor-beta (TGF-beta) in silicosis
    • Jagirdar, J., et al.: Transforming growth factor-beta (TGF-beta) in silicosis. Am J Respir Crit Care Med, 1996,154(4 Pt 1): p. 1076-81.
    • (1996) Am J Respir Crit Care Med , vol.154 , Issue.4 PART 1 , pp. 1076-1081
    • Jagirdar, J.1
  • 53
    • 0004228949 scopus 로고
    • Occupational Lung Diseases
    • WB Saunders
    • Morgan, W.; Seaton, A.: Occupational Lung Diseases, 1975, Philadelphia, Pa: WB Saunders. 149-210.
    • (1975) Philadelphia, Pa , pp. 149-210
    • Morgan, W.1    Seaton, A.2
  • 54
    • 0033824480 scopus 로고    scopus 로고
    • Silicosis and coal workers' pneumoconiosis
    • Castranova, V.; Vallyathan, V.: Silicosis and coal workers' pneumoconiosis. Environ Health Perspect, 2000, 108 Suppl 4: p. 675-84.
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 4 , pp. 675-684
    • Castranova, V.1    Vallyathan, V.2
  • 55
    • 0031714993 scopus 로고    scopus 로고
    • Polymorphisms in the promoter of the tumor necrosis factor-alpha gene in coal miners
    • Zhai, R., et al.: Polymorphisms in the promoter of the tumor necrosis factor-alpha gene in coal miners. Am J Ind Med, 1998, 34(4): p. 318-24.
    • (1998) Am J Ind Med , vol.34 , Issue.4 , pp. 318-324
    • Zhai, R.1
  • 56
    • 0035312568 scopus 로고    scopus 로고
    • Association of tumor necrosis factor-alpha and interleukin-1 gene polymorphisms with silicosis
    • Yucesoy, B., et al.: Association of tumor necrosis factor-alpha and interleukin-1 gene polymorphisms with silicosis. Toxicol Appl Pharmacol, 2001, 172(1): p75-82.
    • (2001) Toxicol Appl Pharmacol , vol.172 , Issue.1 , pp. 75-82
    • Yucesoy, B.1
  • 57
    • 4243238312 scopus 로고    scopus 로고
    • Cytokine polymorphisms in silicosis and other pneumoconioses
    • Yucesoy, B., et al.: Cytokine polymorphisms in silicosis and other pneumoconioses. Mol Cell Biochem, 2002, 234-235(1-2): p. 219-24.
    • (2002) Mol Cell Biochem , vol.234-235 , Issue.1-2 , pp. 219-224
    • Yucesoy, B.1
  • 58
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter, J. C., et al.: The sequence of the human genome. Science, 2001, 291(5507): p. 1304-51.
    • (2001) Science , vol.291 , Issue.5507 , pp. 1304-1351
    • Venter, J.C.1
  • 59
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander, E. S., et al.: Initial sequencing and analysis of the human genome. Nature, 2001, 409(6822): p. 860-921.
    • (2001) Nature , vol.409 , Issue.6822 , pp. 860-921
    • Lander, E.S.1
  • 60
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium
    • International HapMap Consortium, A haplotype map of the human genome. Nature, 2005, 437(7063): p. 1299-320.
    • (2005) Nature , vol.437 , Issue.7063 , pp. 1299-1320
  • 61
    • 34447126839 scopus 로고    scopus 로고
    • CD14, endotoxin, and asthma risk: Actions and interactions
    • Martinez, F. D.: CD14, endotoxin, and asthma risk: actions and interactions. Proc Am Thorac Soc, 2007, 4(3): p. 221-5.
    • (2007) Proc Am Thorac Soc , vol.4 , Issue.3 , pp. 221-225
    • Martinez, F.D.1
  • 62
    • 34548709584 scopus 로고    scopus 로고
    • Genetic variation in S-nitrosoglutathione reductase (GSNOR) and childhood asthma
    • Wu, H., et al.: Genetic variation in S-nitrosoglutathione reductase (GSNOR) and childhood asthma. J Allergy Clin Immunol, 2007, 120(2): p. 322-8.
    • (2007) J Allergy Clin Immunol , vol.120 , Issue.2 , pp. 322-328
    • Wu, H.1
  • 63
    • 38449122428 scopus 로고    scopus 로고
    • Association of a polymorphism of CYP3A4 with type 2 diabetes mellitus
    • Yamada, Y., et al.: Association of a polymorphism of CYP3A4 with type 2 diabetes mellitus. Int J Mol Med, 2007, 20(5): p. 703-7.
    • (2007) Int J Mol Med , vol.20 , Issue.5 , pp. 703-707
    • Yamada, Y.1
  • 64
    • 35448944056 scopus 로고    scopus 로고
    • Qi, L., et al.: Gene-gene interactions between HNF4A and KCNJ11 in predicting Type 2 diabetes in women. Diabet Med, 2007: p. pp.1187-1191.
    • Qi, L., et al.: Gene-gene interactions between HNF4A and KCNJ11 in predicting Type 2 diabetes in women. Diabet Med, 2007: p. pp.1187-1191.
  • 65
    • 34347393306 scopus 로고    scopus 로고
    • Genetic variation and decreased risk for obesity in the Atherosclerosis Risk in Communities Study
    • Hart Sailors, M. L., et al.: Genetic variation and decreased risk for obesity in the Atherosclerosis Risk in Communities Study. Diabetes Obes Metab, 2007. 9(4): p. 548-57.
    • (2007) Diabetes Obes Metab , vol.9 , Issue.4 , pp. 548-557
    • Hart Sailors, M.L.1
  • 66
    • 34249906772 scopus 로고    scopus 로고
    • Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: A scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group
    • Arnett, D. K., et al.: Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group. Circulation, 2007, 115(22): p. 2878-901.
    • (2007) Circulation , vol.115 , Issue.22 , pp. 2878-2901
    • Arnett, D.K.1
  • 67
    • 0346494642 scopus 로고    scopus 로고
    • The use of "omic" approaches in unraveling mechanisms of gene-environment interactions
    • Olden, K.: The use of "omic" approaches in unraveling mechanisms of gene-environment interactions. Current Genomics, 2004, 5(1): p. 1-6.
    • (2004) Current Genomics , vol.5 , Issue.1 , pp. 1-6
    • Olden, K.1
  • 68
    • 33845635637 scopus 로고    scopus 로고
    • Toxicogenomics - a new systems toxicology approach to understanding of gene-environment interactions
    • Olden, K.: Toxicogenomics - a new systems toxicology approach to understanding of gene-environment interactions. Ann N Y Acad Sci, 2006. 1076: p. 703-6.
    • (2006) Ann N Y Acad Sci , vol.1076 , pp. 703-706
    • Olden, K.1
  • 69
    • 1842784861 scopus 로고    scopus 로고
    • Multidisciplinary research: Strategies for assessing chemical mixtures to reduce risk of exposure and disease
    • Suk, W. A.; Olden, K.: Multidisciplinary research: strategies for assessing chemical mixtures to reduce risk of exposure and disease. Int J Occup Med Environ Health, 2004, 17(1): p. 103-10.
    • (2004) Int J Occup Med Environ Health , vol.17 , Issue.1 , pp. 103-110
    • Suk, W.A.1    Olden, K.2
  • 70
    • 41649100370 scopus 로고    scopus 로고
    • NIEHS, cited 2007 October 14, Available from
    • NIEHS. Environmental Genome Project. 2007 [cited 2007 October 14]; Available from: http://www.niehs.nih.gov/research/supported/programs/egp/.
    • (2007)
  • 71
    • 0034725785 scopus 로고    scopus 로고
    • Toxicogenomics. Toxicologists brace for genomics revolution
    • Lovett, R. A.: Toxicogenomics. Toxicologists brace for genomics revolution. Science, 2000, 289(5479): p. 536-7.
    • (2000) Science , vol.289 , Issue.5479 , pp. 536-537
    • Lovett, R.A.1
  • 72
    • 0037255214 scopus 로고    scopus 로고
    • Waters, M., et al.: Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base. EHP Toxicogenomics, 2003. 111(1T): p. 15-28.
    • Waters, M., et al.: Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base. EHP Toxicogenomics, 2003. 111(1T): p. 15-28.


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