From human genome research to personalized health care

Issues in Science and Technology

Volumn 25, Issue 4, 2009, Pages 51-56

  Omenn, Gilbert S ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES; HEALTH CARE;

CORONARY HEART DISEASE; GENECHIPS; GENOME RESEARCH; GENOME-WIDE ASSOCIATION; HUMAN GENOMES; MACULAR DEGENERATION; MENTAL ILLNESS; PERSONALIZED HEALTHCARE; PRESSURE LEVEL; SINGLE NUCLEOTIDE POLYMORPHISMS;

BLOOD PRESSURE;

EID: 67651174378     PISSN: 07485492     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

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2. C. Auffray, Z. Chen, L. Hood, "Systems Medicine: The Future of Medical Genomics and Healthcare," Genome Medicine I (2009): 2.1-2.13.
3. The Cancer Genome Atlas (TCGA) Research Network, "Comprehensive Genomic Characterization Defines Human Glioblastoma Genes and Core Pathways," Nature 455 (2008): 1061-1068.
4. L. Chun, U. I. Schwarz, M. D. Ritchie, D. M. Roden, C. M. Stein, D. Kurnik, "Relative Contribution of CYP2C9 and VKORC1 Genotype and Early INR Response to the Prediction of Warfarin Sensitivity During Initiation of Therapy," Blood 113 (2009): 3925-3930.
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6. N. T. Hansen, S. Brunak, R. B. Altman, "Generating Genome-Scale Candidate Gene Lists for Pharmacogenomics," Clinical Pharmacology Therapeutics, online publication April 15, 2009, doi:10.1038/clpt.2009.42: 1-7.
7. D. J. Hunter, M. J. Khoury, J. M. Drazen, "Letting the Genome out of the Bottle-Will We Get Our Wish?" New England Journal of Medicine 358 (2008): 105-107.
8. A. G. Motulsky, "If I Had a Gene Test, What Would I Have and Who Would I Tell?" Lancet 354 (1999): SI35-SI37.
9. National Human Genome Research Institute, A Catalog of Published Genome-Wide Association Studies, http://www.genome.gov/GWAstudies/;
10. NIH Genes, Environment and Health Initiative, http://www.gei.nih.gov; and
11. National Heart, Lung, and Blood Institute, STAMPEED: SNP Typing for Association with Multiple Phenotypes from Existing Epidemiologic Data, http://public.nhlbi.nih.gov/GeneticsGenomics/home/stampeed.aspx.
12. D. F. Ransohoff, "Bias As a Threat to the Validity of Cancer Molecular-Marker Research." Nature Reviews Cancer 5 (2005): 142-149. (Pubitemid 40215862)
13. M. A. Rothstein, "Currents in Contemporary Ethics: GINA, the ADA, and Genetic Discrimination in Employment," Journal of Law, Medicine & Ethics (Winter 2008): 837-840.