Methotrexate decreases hippocampal cell proliferation and induces memory deficits in rats

Behavioural Brain Research

Volumn 201, Issue 2, 2009, Pages 279-284

  Seigers, Riejanne ^a   Schagen, Sanne B ^b   Coppens, Caroline M ^a   van der Most, Peter J ^a   van Dam, Frits S A M ^b   Koolhaas, Jaap M ^a   Buwalda, Bauke ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

Author keywords

Hippocampal cell proliferation; Memory deficits; Methotrexate; Rat

Indexed keywords

METHOTREXATE;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIORAL SCIENCE; CELL DEATH; CELL PROLIFERATION; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS CALLOSUM; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING DISORDER; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; WHITE MATTER;

ANALYSIS OF VARIANCE; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ASSOCIATION LEARNING; CELL DEATH; CELL PROLIFERATION; COGNITION; COGNITION DISORDERS; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; FEAR; FOLLOW-UP STUDIES; HIPPOCAMPUS; MAZE LEARNING; METHOTREXATE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 67349085108     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2009.02.025     Document Type: Article

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