Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats

Clinical and Experimental Pharmacology and Physiology

Volumn 37, Issue 10, 2010, Pages 1010-1015

  Tan, Wen Fei ^a   Cao, Xue Zhao ^a   Wang, Jun Ke ^a   Lv, Huang Wei ^a   Wu, Bin Yang ^a   Ma, Hong ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

glycogen synthase kinase 3 ; inflammatory factors; interleukin 1; lithium; tumour necrosis factor

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 1BETA; LITHIUM CHLORIDE; MESSENGER RNA; SERINE; TAU PROTEIN; THREONINE; TUMOR NECROSIS FACTOR ALPHA;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEARNING; MALE; MAZE TEST; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPATIAL MEMORY; SPLENECTOMY; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; GLYCOGEN SYNTHASE KINASE 3; INFLAMMATION MEDIATORS; LITHIUM CHLORIDE; MALE; MAZE LEARNING; MEMORY DISORDERS; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; POSTOPERATIVE COMPLICATIONS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPLENECTOMY; TAU PROTEINS; TREATMENT OUTCOME;

EID: 77957265540     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2010.05433.x     Document Type: Article

References (31)

1. Weingarten MD, Lockwood AH, Hwo SY, Kirschner MW. A protein factor essential for microtubule assembly. Proc. Natl. Acad. Sci. USA 1975 72 : 1858 62.
2. Grundke-Iqbal I, Iqbal K, Quinlan M, Tung YC, Zaidi MS, Wisniewski HM. Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. J. Biol. Chem. 1986 261 : 6084 9. (Pubitemid 17207447)
3. Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA 1986 83 : 4913 7. (Pubitemid 16075509)
4. Takashima A. GSK-3 is essential in the pathogenesis of Alzheimer's disease. J. Alzheimers Dis. 2006 9 : 309 17. (Pubitemid 44253325)
5. Berger Z, Roder H, Hanna A et al. Accumulation of pathological tau species and memory loss in a conditional model of tauopathy. J. Neurosci. 2007 27 : 3650 62. (Pubitemid 46557687)
6. Kimura T, Yamashita S, Fukuda T et al. Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau. EMBO J. 2007 26 : 5143 52. (Pubitemid 350261280)
7. Ramsden M, Kotilinek L, Forster C et al. Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L). J. Neurosci. 2005 25 : 10637 47. (Pubitemid 41681911)
8. Pennanen L, Wolfer DP, Nitsch RM, Gotz J. Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice. Genes Brain Behav. 2006 5 : 369 79. (Pubitemid 44000922)
9. Santacruz K, Lewis J, Spires T et al. Tau suppression in a neurodegenerative mouse model improves memory function. Science 2005 309 : 476 81. (Pubitemid 40994688)
10. Boekhoorn K, Terwel D, Biemans B et al. Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy. J. Neurosci. 2006 26 : 3514 23.
11. Godbout JP, Chen J, Abraham J et al. Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system. FASEB J. 2005 19 : 1329 31. (Pubitemid 41113739)
12. Barrientos RM, Higgins EA, Biedenkapp JC et al. Peripheral infection and aging interact to impair hippocampal memory consolidation. Neurobiol. Aging 2006 27 : 723 32.
13. Buchanan JB, Sparkman NL, Chen J, Johnson RW. Cognitive and neuroinflammatory consequences of mild repeated stress are exacerbated in aged mice. Psychoneuroendocrinology 2008 33 : 755 65.
14. Chen J, Buchanan JB, Sparkman NL, Godbout JP, Freund GG, Johnson RW. Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system. Brain Behav. Immun. 2008 22 : 301 11. (Pubitemid 351172703)
15. Li Y, Liu L, Barger SW, Griffin WS. Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J. Neurosci. 2003 23 : 1605 11. (Pubitemid 36314715)
16. Eto M, Kouroedov A, Cosentino F, Luscher TF. Glycogen synthase kinase-3β mediates endothelial cell activation by tumor necrosis factor-alpha. Circulation 2005 112 : 1316 22. (Pubitemid 41266727)
17. Tsaltas E, Kontis D, Boulougouris V, Papadimitriou GN. Lithium and cognitive enhancement: Leave it or take it. Psychopharmacology (Berl.) 2009 202 : 457 76.
18. Schmitt WB, Deacon RM, Seeburg PH, Rawlins JN, Bannerman DM. A within-subjects, within-task demonstration of intact spatial reference memory and impaired spatial working memory in glutamate receptor-A-deficient mice. J. Neurosci. 2003 23 : 3953 9.
19. Riedel G, Wetzel W, Reymann KG. Computer-assisted shock-reinforced Y-maze training: A method for studying spatial alternation behaviour. Neuroreport 1994 5 : 2061 4. (Pubitemid 24340070)
20. Packard MG, McGaugh JL. Inactivation of hippocampus or caudate nucleus with lidocaine differentially affects expression of place and response learning. Neurobiol. Learn. Mem. 1996 65 : 65 72.
21. Loepke AW, Istaphanous GK, McAuliffe JJ III. et al. The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory. Anaesth. Analg. 2009 108 : 90 104.
22. Tung A, Herrera S, Fornal CA, Jacobs BL. The effect of prolonged anaesthesia with isoflurane, propofol, dexmedetomidine, or ketamine on neural cell proliferation in the adult rat. Anaesth Analg 2008 106 : 1772 7.
23. Bilbo SD, Barrientos RM, Eads AS et al. Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. Brain Behav. Immun. 2008 22 : 451 5.
24. Richwine AF, Parkin AO, Buchanan JB et al. Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulation. Psychoneuroendocrinology 2008 33 : 1369 77.
25. Grimes CA, Jope RS. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog. Neurobiol. 2001 65 : 391 426.
26. Engel T, Hernandez F, Avila J, Lucas JJ. Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3β. J. Neurosci. 2006 26 : 5083 90. (Pubitemid 44315289)
27. Liu SJ, Zhang AH, Li HL et al. Overactivation of glycogen synthase kinase-3β by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. J. Neurochem. 2003 87 : 1333 44.
28. Noble W, Planel E, Zehr C et al. Inhibition of glycogen synthase kinase-3β by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl. Acad. Sci. USA 2005 102 : 6990 5. (Pubitemid 40675429)
29. Phiel CJ, Klein PS. Molecular targets of lithium action. Annu. Rev. Pharmacol. Toxicol. 2001 41 : 789 813.
30. Zhang F, Phiel CJ, Spece L, Gurvich N, Klein PS. Inhibitory phosphorylation of glycogen synthase kinase-3β (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3. J. Biol. Chem. 2003 278 : 33067 77. (Pubitemid 37055753)
31. Rametti A, Esclaire F, Yardin C, Cogne N, Terro F. Lithium down-regulates tau in cultured cortical neurons: A possible mechanism of neuroprotection. Neurosci. Lett. 2008 434 : 93 8.