Mutation location effect on severity of phenotype during exercise testing in type 1 long-QT syndrome: Impact of transmembrane and C-loop location

Journal of Cardiovascular Electrophysiology

Volumn 24, Issue 9, 2013, Pages 1015-1020

  Laksman, Zachary W M ^a   Hamilton, Robert M ^c   Chockalingam, Priya ^d   Ballantyne, Emily ^a   Stephenson, Elizabeth A ^c   Gross, Gil J ^c   Gula, Lorne J ^a   Klein, George J ^a   Wilde, Arthur A M ^c   Krahn, Andrew D ^b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

diagnosis; exercise; genetics; genotype; long QT syndrome; LQT1; phenotype

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; POTASSIUM CHANNEL KCNQ1;

ADRENERGIC STIMULATION; ADULT; ARTICLE; BINDING SITE; CLINICAL OBSERVATION; CONTROLLED STUDY; CONVALESCENCE; DISEASE SEVERITY; EXERCISE TEST; FAINTNESS; FEMALE; HUMAN; LONG QT SYNDROME 1; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MISSENSE MUTATION; MULTICENTER STUDY; PATIENT REFERRAL; PHENOTYPE; PRIORITY JOURNAL; QRS COMPLEX; QT INTERVAL; RISK FACTOR; STANDING; SUDDEN CARDIAC DEATH; SUPINE POSITION; TREADMILL EXERCISE; TREATMENT RESPONSE;

DIAGNOSIS; EXERCISE; GENETICS; GENOTYPE; LONG-QT SYNDROME; LQT1; PHENOTYPE;

ADOLESCENT; ADULT; CELL MEMBRANE; COHORT STUDIES; EXERCISE TEST; FEMALE; HUMANS; KCNQ1 POTASSIUM CHANNEL; MALE; MIDDLE AGED; MUTATION, MISSENSE; PHENOTYPE; RETROSPECTIVE STUDIES; ROMANO-WARD SYNDROME; YOUNG ADULT;

EID: 84883800397     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/jce.12172     Document Type: Article

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