-
1
-
-
0035801373
-
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
-
Le Hir H,Gatfield D,Izaurralde E,Moore MJ.The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.Embo J. 2001;20:4987-97.
-
(2001)
Embo J
, vol.20
, pp. 4987-4997
-
-
Le Hir, H.1
Gatfield, D.2
Izaurralde, E.3
Moore, M.J.4
-
2
-
-
0035823150
-
Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
-
Kim VN,Kataoka N,Dreyfuss G.Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex.Science. 2001;293:1832-6.
-
(2001)
Science
, vol.293
, pp. 1832-1836
-
-
Kim, V.N.1
Kataoka, N.2
Dreyfuss, G.3
-
3
-
-
0035901565
-
The Y14 protein communicates to the cytoplasm the position of exon-exon junctions
-
Kim VN,Yong J,Kataoka N,Abel L,Diem MD,Dreyfuss G.The Y14 protein communicates to the cytoplasm the position of exon-exon junctions.Embo J. 2001;20:2062-8.
-
(2001)
Embo J
, vol.20
, pp. 2062-2068
-
-
Kim, V.N.1
Yong, J.2
Kataoka, N.3
Abel, L.4
Diem, M.D.5
Dreyfuss, G.6
-
4
-
-
0037046798
-
Translation is required to remove Y14 from mRNAs in the cytoplasm
-
Dostie J,Dreyfuss G.Translation is required to remove Y14 from mRNAs in the cytoplasm.Curr Biol. 2002;12:1060-7.
-
(2002)
Curr Biol
, vol.12
, pp. 1060-1067
-
-
Dostie, J.1
Dreyfuss, G.2
-
5
-
-
3543032700
-
Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex
-
Bono F,Ebert J,Unterholzner L,Guttler T,Izaurralde E,Conti E.Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex.Embo Rep. 2004;5:304-10.
-
(2004)
Embo Rep
, vol.5
, pp. 304-310
-
-
Bono, F.1
Ebert, J.2
Unterholzner, L.3
Guttler, T.4
Izaurralde, E.5
Conti, E.6
-
6
-
-
66249134562
-
The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay
-
Gehring NH,Lamprinaki S,Hentze MW,Kulozik AE.The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay.PLoS Biol. 2009;7:e1000120-e1000120.
-
(2009)
PLoS Biol
, vol.7
-
-
Gehring, N.H.1
Lamprinaki, S.2
Hentze, M.W.3
Kulozik, A.E.4
-
7
-
-
63149195971
-
The exon-junction complex proteins, Y14 and MAGOH regulate STAT3 activation
-
Muromoto R,Taira N,Ikeda O,Shiga K,Kamitani S,Togi S,Kawakami S,Sekine Y,Nanbo A,Oritani K,Matsuda T.The exon-junction complex proteins, Y14 and MAGOH regulate STAT3 activation.Biochem Biophys Res Commun. 2009;382:63-8.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 63-68
-
-
Muromoto, R.1
Taira, N.2
Ikeda, O.3
Shiga, K.4
Kamitani, S.5
Togi, S.6
Kawakami, S.7
Sekine, Y.8
Nanbo, A.9
Oritani, K.10
Matsuda, T.11
-
8
-
-
44749085781
-
An RNA biding protein, Y14 interacts with and modulates STAT3 activation
-
Ohbayashi N,Taira N,Kawakami S,Togi S,Sato N,Ikeda O,Kamitani S,Muromoto R,Sekine Y,Matsuda T.An RNA biding protein, Y14 interacts with and modulates STAT3 activation.Biochem Biophys Res Commun. 2008;372:475-9.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 475-479
-
-
Ohbayashi, N.1
Taira, N.2
Kawakami, S.3
Togi, S.4
Sato, N.5
Ikeda, O.6
Kamitani, S.7
Muromoto, R.8
Sekine, Y.9
Matsuda, T.10
-
9
-
-
77950339287
-
Knockdown of COPA, identified by loss-of-function screen, induces apoptosis and suppresses tumor growth in mesothelioma mouse model
-
Sudo H,Tsuji AB,Sugyo A,Kohda M,Sogawa C,Yoshida C,Harada YN,Hino O,Saga T.Knockdown of COPA, identified by loss-of-function screen, induces apoptosis and suppresses tumor growth in mesothelioma mouse model.Genomics. 2010;95:210-6.
-
(2010)
Genomics
, vol.95
, pp. 210-216
-
-
Sudo, H.1
Tsuji, A.B.2
Sugyo, A.3
Kohda, M.4
Sogawa, C.5
Yoshida, C.6
Harada, Y.N.7
Hino, O.8
Saga, T.9
-
10
-
-
77951667779
-
The exon junction complex component Magoh controls brain size by regulating neural stem cell division
-
Silver DL,Watkins-Chow DE,Schreck KC,Pierfelice TJ,Larson DM,Burnetti AJ,Liaw H-J,Myung K,Walsh CA,Gaiano N,Pavan WJ.The exon junction complex component Magoh controls brain size by regulating neural stem cell division.Nat Neurosci. 2010;13:551-8.
-
(2010)
Nat Neurosci
, vol.13
, pp. 551-558
-
-
Silver, D.L.1
Watkins-Chow, D.E.2
Schreck, K.C.3
Pierfelice, T.J.4
Larson, D.M.5
Burnetti, A.J.6
Liaw, H.-J.7
Myung, K.8
Walsh, C.A.9
Gaiano, N.10
Pavan, W.J.11
-
11
-
-
78751688115
-
Genetic analyses using a mouse cell cycle mutant identifies magoh as a novel gene involved in Cdk regulation
-
Inaki M,Kato D,Utsugi T,Onoda F,Hanaoka F,Murakami Y.Genetic analyses using a mouse cell cycle mutant identifies magoh as a novel gene involved in Cdk regulation.Genes Cells. 2011;16:166-78.
-
(2011)
Genes Cells
, vol.16
, pp. 166-168
-
-
Inaki, M.1
Kato, D.2
Utsugi, T.3
Onoda, F.4
Hanaoka, F.5
Murakami, Y.6
-
12
-
-
84863393160
-
Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome
-
S1-S2
-
Albers CA,Paul DS,Schulze H,Freson K,Stephens JC,Smethurst PA,Jolley JD,Cvejic A,Kostadima M,Bertone P,Breuning MH,Debili N,Deloukas P,Favier R,Fiedler J,Hobbs CM,Huang N,Hurles ME,Kiddle G,Krapels I,Nurden P,Ruivenkamp CAL,Sambrook JG,Smith K,Stemple DL,Strauss G,Thys C,van Geet C,Newbury-Ecob R,Ouwehand WH,Ghevaert C.Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome.Nat Genet. 2012;44:435-9, S1-2.
-
(2012)
Nat Genet
, vol.44
, pp. 435-439
-
-
Albers, C.A.1
Paul, D.S.2
Schulze, H.3
Freson, K.4
Stephens, J.C.5
Smethurst, P.A.6
Jolley, J.D.7
Cvejic, A.8
Kostadima, M.9
Bertone, P.10
Breuning, M.H.11
Debili, N.12
Deloukas, P.13
Favier, R.14
Fiedler, J.15
Hobbs, C.M.16
Huang, N.17
Hurles, M.E.18
Kiddle, G.19
Krapels, I.20
Nurden, P.21
Ruivenkamp, C.A.L.22
Sambrook, J.G.23
Smith, K.24
Stemple, D.L.25
Strauss, G.26
Thys, C.27
van Geet, C.28
Newbury-Ecob, R.29
Ouwehand, W.H.30
Ghevaert, C.31
more..
-
13
-
-
0034710315
-
Cloning and gene expression of a novel human ribonucleoprotein
-
Conklin DC,Rixon MW,Kuestner RE,Maurer MF,Whitmore TE,Millar RP.Cloning and gene expression of a novel human ribonucleoprotein.Biochim Biophys Acta. 2000;1492:465-9.
-
(2000)
Biochim Biophys Acta
, vol.1492
, pp. 465-469
-
-
Conklin, D.C.1
Rixon, M.W.2
Kuestner, R.E.3
Maurer, M.F.4
Whitmore, T.E.5
Millar, R.P.6
-
14
-
-
0036289298
-
Conserved physical linkage of GnRH-R and RBM8 in the medaka and human genomes
-
Okubo K,Mitani H,Naruse K,Kondo M,Shima A,Tanaka M,Aida K.Conserved physical linkage of GnRH-R and RBM8 in the medaka and human genomes.Biochem Biophys Res Commun. 2002;293:327-31.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 327-331
-
-
Okubo, K.1
Mitani, H.2
Naruse, K.3
Kondo, M.4
Shima, A.5
Tanaka, M.6
Aida, K.7
-
15
-
-
42249084413
-
Multiple shRNA expressions in a single plasmid vector improve RNAi against the XPA gene
-
Nagao A,Zhao X,Takegami T,Nakagawa H,Matsui S,Matsunaga T,Ishigaki Y.Multiple shRNA expressions in a single plasmid vector improve RNAi against the XPA gene.Biochem Biophys Res Commun. 2008;370:301-5.
-
(2008)
Biochem Biophys Res Commun
, vol.370
, pp. 301-305
-
-
Nagao, A.1
Zhao, X.2
Takegami, T.3
Nakagawa, H.4
Matsui, S.5
Matsunaga, T.6
Ishigaki, Y.7
-
16
-
-
80155179665
-
Scanning electron microscopy with an ionic liquid reveals the loss of mitotic protrusions of cells during the epithelial-mesenchymal transition
-
Ishigaki Y,Nakamura Y,Takehara T,Shimasaki T,Tatsuno T,Takano F,Ueda Y,Motoo Y,Takegami T,Nakagawa H,Kuwabata S,Nemoto N,Tomosugi N,Miyazawa S.Scanning electron microscopy with an ionic liquid reveals the loss of mitotic protrusions of cells during the epithelial-mesenchymal transition.Microsc Res Tech. 2011;74:1024-31.
-
(2011)
Microsc Res Tech
, vol.74
, pp. 1024-1031
-
-
Ishigaki, Y.1
Nakamura, Y.2
Takehara, T.3
Shimasaki, T.4
Tatsuno, T.5
Takano, F.6
Ueda, Y.7
Motoo, Y.8
Takegami, T.9
Nakagawa, H.10
Kuwabata, S.11
Nemoto, N.12
Tomosugi, N.13
Miyazawa, S.14
-
17
-
-
0030828073
-
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
-
Hendzel MJ,Wei Y,Mancini MA,Van Hooser A,Ranalli T,Brinkley BR,Bazett-Jones DP,Allis CD.Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation.Chromosoma. 1997;106:348-60.
-
(1997)
Chromosoma
, vol.106
, pp. 348-360
-
-
Hendzel, M.J.1
Wei, Y.2
Mancini, M.A.3
van Hooser, A.4
Ranalli, T.5
Brinkley, B.R.6
Bazett-Jones, D.P.7
Allis, C.D.8
-
18
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW,Ali A,Thornberry NA,Vaillancourt JP,Ding CK,Gallant M,Gareau Y,Griffin PR,Labelle M,Lazebnik YA,Munday NA,Raju SM,Smulson ME,Yamin TT,Yu VL,Miller DK.Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis.Nature. 1995;376:37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
Munday, N.A.11
Raju, S.M.12
Smulson, M.E.13
Yamin, T.T.14
Yu, V.L.15
Miller, D.K.16
-
19
-
-
0030044012
-
Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32
-
Lippke JA,Gu Y,Sarnecki C,Caron PR,Su MS.Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32.J Biol Chem. 1996;271:1825-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 1825-1828
-
-
Lippke, J.A.1
Gu, Y.2
Sarnecki, C.3
Caron, P.R.4
Su, M.S.5
-
20
-
-
0028884167
-
Mch3, a novel human apoptotic cysteine protease highly related to CPP32
-
Fernandes-Alnemri T,Takahashi A,Armstrong R,Krebs J,Fritz L,Tomaselli KJ,Wang L,Yu Z,Croce CM,Salveson G,Earnshaw WC,Litwack G,Alnemri ES.Mch3, a novel human apoptotic cysteine protease highly related to CPP32.Cancer Res. 1995;55:6045-52.
-
(1995)
Cancer Res
, vol.55
, pp. 6045-6052
-
-
Fernandes-Alnemri, T.1
Takahashi, A.2
Armstrong, R.3
Krebs, J.4
Fritz, L.5
Tomaselli, K.J.6
Wang, L.7
Yu, Z.8
Croce, C.M.9
Salveson, G.10
Earnshaw, W.C.11
Litwack, G.12
Alnemri, E.S.13
-
21
-
-
4744373469
-
Stat3 activity is required for centrosome duplication in chinese hamster ovary cells
-
Metge B,Ofori-Acquah S,Stevens T,Balczon R.Stat3 activity is required for centrosome duplication in chinese hamster ovary cells.J Biol Chem. 2004;279:41801-6.
-
(2004)
J Biol Chem
, vol.279
, pp. 41801-41806
-
-
Metge, B.1
Ofori-Acquah, S.2
Stevens, T.3
Balczon, R.4
-
22
-
-
32044454232
-
hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay
-
Wittmann J,Hol EM,Jack HM.hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay.Mol Cell Biol. 2006;26:1272-87.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1272-1287
-
-
Wittmann, J.1
Hol, E.M.2
Jack, H.M.3
-
23
-
-
44149104364
-
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
-
Weischenfeldt J,Damgaard I,Bryder D,Theilgaard-Monch K,Thoren LA,Nielsen FC,Jacobsen SEW,Nerlov C,Porse BT.NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.Genes Dev. 2008;22:1381-96.
-
(2008)
Genes Dev
, vol.22
, pp. 1381-1396
-
-
Weischenfeldt, J.1
Damgaard, I.2
Bryder, D.3
Theilgaard-Monch, K.4
Thoren, L.A.5
Nielsen, F.C.6
Jacobsen, S.E.W.7
Nerlov, C.8
Porse, B.T.9
-
24
-
-
67650096774
-
Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival
-
Wittkopp N,Huntzinger E,Weiler C,Sauliere J,Schmidt S,Sonawane M,Izaurralde E.Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival.Mol Cell Biol. 2009;29:3517-28.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3517-3528
-
-
Wittkopp, N.1
Huntzinger, E.2
Weiler, C.3
Sauliere, J.4
Schmidt, S.5
Sonawane, M.6
Izaurralde, E.7
-
25
-
-
34548353924
-
Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation
-
Tarpey PS,Raymond FL,Nguyen LS,Rodriguez J,Hackett A,Vandeleur L,Smith R,Shoubridge C,Edkins S,Stevens C,O'Meara S,Tofts C,Barthorpe S,Buck G,Cole J,Halliday K,Hills K,Jones D,Mironenko T,Perry J,Varian J,West S,Widaa S,Teague J,Dicks E,Butler A,Menzies A,Richardson D,Jenkinson A,Shepherd R,Raine K,Moon J,Luo Y,Parnau J,Bhat S,Gardner A,Corbett M,Brooks D,Thomas P,Parkinson-Lawrence E,Porteous ME,Warner JP,Sanderson T,Pearson P,Simensen RJ,Skinner C,Hoganson G,Superneau D,Wooster R,Bobrow M,Turner G,Stevenson RE,Schwartzn CE,Futreal PA,Srivastava AK,Stratton MR,Gécz J.Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation.Nat Genet. 2007;39:1127-33.
-
(2007)
Nat Genet
, vol.39
, pp. 1127-1133
-
-
Tarpey, P.S.1
Raymond, F.L.2
Nguyen, L.S.3
Rodriguez, J.4
Hackett, A.5
Vandeleur, L.6
Smith, R.7
Shoubridge, C.8
Edkins, S.9
Stevens, C.10
O'Meara, S.11
Tofts, C.12
Barthorpe, S.13
Buck, G.14
Cole, J.15
Halliday, K.16
Hills, K.17
Jones, D.18
Mironenko, T.19
Perry, J.20
Varian, J.21
West, S.22
Widaa, S.23
Teague, J.24
Dicks, E.25
Butler, A.26
Menzies, A.27
Richardson, D.28
Jenkinson, A.29
Shepherd, R.30
Raine, K.31
Moon, J.32
Luo, Y.33
Parnau, J.34
Bhat, S.35
Gardner, A.36
Corbett, M.37
Brooks, D.38
Thomas, P.39
Parkinson-Lawrence, E.40
Porteous, M.E.41
Warner, J.P.42
Sanderson, T.43
Pearson, P.44
Simensen, R.J.45
Skinner, C.46
Hoganson, G.47
Superneau, D.48
Wooster, R.49
Bobrow, M.50
Turner, G.51
Stevenson, R.E.52
Schwartzn, C.E.53
Futreal, P.A.54
Srivastava, A.K.55
Stratton, M.R.56
Gécz, J.57
more..
-
26
-
-
32944458421
-
The human RNA surveillance factor UPF1 is required for S phase progression and genome stability
-
Azzalin CM,Lingner J.The human RNA surveillance factor UPF1 is required for S phase progression and genome stability.Curr Biol. 2006;16:433-9.
-
(2006)
Curr Biol
, vol.16
, pp. 433-439
-
-
Azzalin, C.M.1
Lingner, J.2
-
27
-
-
2942572923
-
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells
-
Brumbaugh KM,Otterness DM,Geisen C,Oliveira V,Brognard J,Li X,Lejeune F,Maquat LE,Abraham RT.The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells.Mol Cell. 2004;14:585-98.
-
(2004)
Mol Cell
, vol.14
, pp. 585-598
-
-
Brumbaugh, K.M.1
Otterness, D.M.2
Geisen, C.3
Oliveira, V.4
Brognard, J.5
Li, X.6
Lejeune, F.7
Maquat, L.E.8
Abraham, R.T.9
-
28
-
-
46449097470
-
hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress
-
Gehen SC,Staversky RJ,Bambara RA,Keng PC,O'Reilly MA.hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.Oncogene. 2008;27:4065-74.
-
(2008)
Oncogene
, vol.27
, pp. 4065-4074
-
-
Gehen, S.C.1
Staversky, R.J.2
Bambara, R.A.3
Keng, P.C.4
O'Reilly, M.A.5
-
29
-
-
78650943486
-
Human SMG-1 is involved in gemcitabine-induced primary microRNA-155/BIC up-regulation in human pancreatic cancer PANC-1 cells
-
Xia QS,Ishigaki Y,Zhao X,Shimasaki T,Nakajima H,Nakagawa H,Takegami T,Chen Z,Motoo Y.Human SMG-1 is involved in gemcitabine-induced primary microRNA-155/BIC up-regulation in human pancreatic cancer PANC-1 cells.Pancreas. 2011;40:55-60.
-
(2011)
Pancreas
, vol.40
, pp. 55-60
-
-
Xia, Q.S.1
Ishigaki, Y.2
Zhao, X.3
Shimasaki, T.4
Nakajima, H.5
Nakagawa, H.6
Takegami, T.7
Chen, Z.8
Motoo, Y.9
-
30
-
-
31544467089
-
CB694, a novel antimitotic with antitumor activities
-
Weiderhold KN,Randall-Hlubek DA,Polin LA,Hamel E,Mooberry SL.CB694, a novel antimitotic with antitumor activities.Int J Cancer. 2006;118:1032-40.
-
(2006)
Int J Cancer
, vol.118
, pp. 1032-1040
-
-
Weiderhold, K.N.1
Randall-Hlubek, D.A.2
Polin, L.A.3
Hamel, E.4
Mooberry, S.L.5
-
31
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
Jordan MA,Wilson L.Microtubules as a target for anticancer drugs.Nature Rev Cancer. 2004;4:253-65.
-
(2004)
Nature Rev Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
|