The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay

PLoS Biology

Volumn 7, Issue 5, 2009, Pages

  Gehring, Niels H ^a,b   Lamprinaki, Styliani ^a,b   Hentze, Matthias W ^a,b   Kulozik, Andreas E ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; CASC3 PROTEIN, HUMAN; DEAD BOX PROTEIN; EIF4A3 PROTEIN, HUMAN; MAGOH PROTEIN, HUMAN; NUCLEAR PROTEIN; TUMOR PROTEIN;

ARTICLE; CONTROLLED STUDY; EXON; HUMAN; HUMAN CELL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; RNA ANALYSIS; RNA SPLICING; RNA STABILITY; RNA TRANSLATION; SPLICEOSOME; STRUCTURE ANALYSIS; ANIMAL; GENETIC TRANSFECTION; GENETICS; HELA CELL; METABOLISM; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

MAMMALIA;

ANIMALS; DEAD-BOX RNA HELICASES; EXONS; HELA CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; NUCLEAR PROTEINS; RNA STABILITY; RNA, MESSENGER; SPLICEOSOMES; TRANSFECTION;

EID: 66249134562     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1000120     Document Type: Article

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