Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 36, 2009, Pages 15279-15284

  Yu, Ching Yung ^a,b   Chae, Jeiwook ^c   Buehler, Markus J ^d   Hunter, Craig P ^c   Mooney, David J ^a,c  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c HARVARD UNIVERSITY   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Angiogenesis; Angiopoietin 2; Endothelial cells; shRNA; Strain gradient

Indexed keywords

ANGIOGENIC FACTOR; ANGIOPOIETIN; GROWTH FACTOR; SHORT HAIRPIN RNA;

ANGIOGENESIS; ARTICLE; AUTOCRINE EFFECT; BLOOD VESSEL; CELL TYPE; HUMAN; HUMAN CELL; MECHANOTRANSDUCTION; PARACRINE SIGNALING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TENSILE STRENGTH; UMBILICAL VEIN; UPREGULATION;

AUTOCRINE COMMUNICATION; BIOMECHANICS; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; PARACRINE COMMUNICATION; STRESS, MECHANICAL; UMBILICAL VEINS;

EID: 70349313632     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0905891106     Document Type: Article

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