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Volumn 64, Issue 4, 2013, Pages 610-621

Future direction in pharmacotherapy for non-neurogenic male lower urinary tract symptoms

Author keywords

Benign prostatic hyperplasia; Bladder; Lower urinary tract symptoms; Male; Pathophysiology; Pharmacotherapy; Prostate

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ADRENERGIC RECEPTOR STIMULATING AGENT; ALFUZOSIN; ANTIANDROGEN; CETRORELIX; CHOLINERGIC RECEPTOR STIMULATING AGENT; DOXAZOSIN; DUTASTERIDE; ELOCALCITOL; FINASTERIDE; GISADENAFIL; GONADORELIN; GONADORELIN ANTAGONIST; IMATINIB; MIRABEGRON; MUSCARINIC RECEPTOR BLOCKING AGENT; NAFTOPIDIL; NIFEDIPINE; NORADRENALIN; PHOSPHODIESTERASE V INHIBITOR; PROTEIN KINASE C INHIBITOR; RESINIFERATOXIN; ROFECOXIB; SILDENAFIL; SOLABEGRON; TADALAFIL; TAMSULOSIN; TENOXICAM; TOLTERODINE; UNINDEXED DRUG; VARDENAFIL;

EID: 84883764805     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2013.04.042     Document Type: Review
Times cited : (58)

References (127)
  • 1
    • 0036186813 scopus 로고    scopus 로고
    • The standardisation of terminology of lower urinary tract function: Report from the Standardisation Sub-committee of the International Continence Society
    • P. Abrams, L. Cardozo, and M. Fall The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society Neurourol Urodyn 21 2002 167 178
    • (2002) Neurourol Urodyn , vol.21 , pp. 167-178
    • Abrams, P.1    Cardozo, L.2    Fall, M.3
  • 2
    • 33644872094 scopus 로고    scopus 로고
    • A shifted paradigm for the further understanding, evaluation, and treatment of lower urinary tract symptoms in men: Focus on the bladder
    • C.R. Chapple, and C.G. Roehrborn A shifted paradigm for the further understanding, evaluation, and treatment of lower urinary tract symptoms in men: focus on the bladder Eur Urol 49 2006 651 659
    • (2006) Eur Urol , vol.49 , pp. 651-659
    • Chapple, C.R.1    Roehrborn, C.G.2
  • 3
    • 70349269052 scopus 로고    scopus 로고
    • A refocus on the bladder as the originator of storage lower urinary tract symptoms: A systematic review of the latest literature
    • A. Roosen, C.R. Chapple, and R.R. Dmochowski A refocus on the bladder as the originator of storage lower urinary tract symptoms: a systematic review of the latest literature Eur Urol 56 2009 810 820
    • (2009) Eur Urol , vol.56 , pp. 810-820
    • Roosen, A.1    Chapple, C.R.2    Dmochowski, R.R.3
  • 4
    • 0021149603 scopus 로고
    • The development of human benign prostatic hyperplasia with age
    • S.J. Berry, D.S. Coffey, P.C. Walsh, and L.L. Ewing The development of human benign prostatic hyperplasia with age J Urol 132 1984 474 479
    • (1984) J Urol , vol.132 , pp. 474-479
    • Berry, S.J.1    Coffey, D.S.2    Walsh, P.C.3    Ewing, L.L.4
  • 5
    • 33847239396 scopus 로고    scopus 로고
    • Benign prostatic hyperplasia: An overview
    • C.G. Roehrborn Benign prostatic hyperplasia: an overview Rev Urol 7 Suppl 9 2005 S3 S14
    • (2005) Rev Urol , vol.7 , Issue.SUPPL. 9
    • Roehrborn, C.G.1
  • 6
    • 0035852456 scopus 로고    scopus 로고
    • Benign prostatic hyperplasia has precise meaning
    • P. Abrams Benign prostatic hyperplasia has precise meaning BMJ 322 2001 106
    • (2001) BMJ , vol.322 , pp. 106
    • Abrams, P.1
  • 7
    • 11144221994 scopus 로고    scopus 로고
    • Serum prostate-specific antigen to predict the presence of bladder outlet obstruction in men with urinary symptoms
    • M.E. Laniado, J.L. Ockrim, A. Marronaro, A. Tubaro, and S.S. Carter Serum prostate-specific antigen to predict the presence of bladder outlet obstruction in men with urinary symptoms BJU Int 94 2004 1283 1286
    • (2004) BJU Int , vol.94 , pp. 1283-1286
    • Laniado, M.E.1    Ockrim, J.L.2    Marronaro, A.3    Tubaro, A.4    Carter, S.S.5
  • 8
    • 0035664491 scopus 로고    scopus 로고
    • Symptoms, prostate volume, and urodynamic findings in elderly male volunteers without and with LUTS and in patients with LUTS suggestive of benign prostatic hyperplasia
    • M.D. Eckhardt, G.E. van Venrooij, and T.A. Boon Symptoms, prostate volume, and urodynamic findings in elderly male volunteers without and with LUTS and in patients with LUTS suggestive of benign prostatic hyperplasia Urology 58 2001 966 971
    • (2001) Urology , vol.58 , pp. 966-971
    • Eckhardt, M.D.1    Van Venrooij, G.E.2    Boon, T.A.3
  • 9
    • 72049084993 scopus 로고    scopus 로고
    • Outline of 3,830 male patients referred to urodynamic evaluation for lower urinary tract symptoms: How common is infravesical outlet obstruction?
    • P. Rodrigues, F. Hering, A. Meller, and M. D'Imperio Outline of 3,830 male patients referred to urodynamic evaluation for lower urinary tract symptoms: how common is infravesical outlet obstruction? Urol Int 83 2009 404 409
    • (2009) Urol Int , vol.83 , pp. 404-409
    • Rodrigues, P.1    Hering, F.2    Meller, A.3    D'Imperio, M.4
  • 10
    • 71249160013 scopus 로고    scopus 로고
    • Different evolution of voiding function in underactive bladders with and without detrusor overactivity
    • A. Cucchi, S. Quaglini, and B. Rovereto Different evolution of voiding function in underactive bladders with and without detrusor overactivity J Urol 183 2010 229 233
    • (2010) J Urol , vol.183 , pp. 229-233
    • Cucchi, A.1    Quaglini, S.2    Rovereto, B.3
  • 11
    • 84867916016 scopus 로고    scopus 로고
    • Systematic review of therapy for men with overactive bladder
    • C. Chapple Systematic review of therapy for men with overactive bladder Can Urol Assoc J 5 2011 S143 S145
    • (2011) Can Urol Assoc J , vol.5
    • Chapple, C.1
  • 12
    • 33750617633 scopus 로고    scopus 로고
    • Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: Results of the EPIC study
    • discussion 1306-15
    • Irwin DE, Milsom I, Hunskaar S, et al. Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur Urol 2006;50:1306-14; discussion 1306-15.
    • (2006) Eur Urol , vol.50 , pp. 1306-1314
    • Irwin, D.E.1    Milsom, I.2    Hunskaar, S.3
  • 13
    • 78649355856 scopus 로고    scopus 로고
    • Male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH)
    • C.G. Roehrborn Male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) Med Clin North Am 95 2011 87 100
    • (2011) Med Clin North Am , vol.95 , pp. 87-100
    • Roehrborn, C.G.1
  • 14
    • 70449536472 scopus 로고    scopus 로고
    • The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study
    • C.G. Roehrborn, P. Siami, and J. Barkin The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study Eur Urol 57 2010 123 131
    • (2010) Eur Urol , vol.57 , pp. 123-131
    • Roehrborn, C.G.1    Siami, P.2    Barkin, J.3
  • 15
    • 0347882750 scopus 로고    scopus 로고
    • The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia
    • J.D. McConnell, C.G. Roehrborn, and O.M. Bautista The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia N Engl J Med 349 2003 2387 2398
    • (2003) N Engl J Med , vol.349 , pp. 2387-2398
    • McConnell, J.D.1    Roehrborn, C.G.2    Bautista, O.M.3
  • 16
    • 79952765099 scopus 로고    scopus 로고
    • Antimuscarinics for treatment of storage lower urinary tract symptoms in men: A systematic review
    • S.A. Kaplan, C.G. Roehrborn, P. Abrams, C.R. Chapple, T. Bavendam, and Z. Guan Antimuscarinics for treatment of storage lower urinary tract symptoms in men: a systematic review Int J Clin Pract 65 2011 487 507
    • (2011) Int J Clin Pract , vol.65 , pp. 487-507
    • Kaplan, S.A.1    Roehrborn, C.G.2    Abrams, P.3    Chapple, C.R.4    Bavendam, T.5    Guan, Z.6
  • 17
    • 79952749220 scopus 로고    scopus 로고
    • Tadalafil for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia: Pathophysiology and mechanism(s) of action
    • K.E. Andersson, W.C. de Groat, and K.T. McVary Tadalafil for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia: pathophysiology and mechanism(s) of action Neurourol Urodyn 30 2011 292 301
    • (2011) Neurourol Urodyn , vol.30 , pp. 292-301
    • Andersson, K.E.1    De Groat, W.C.2    McVary, K.T.3
  • 18
    • 84867048874 scopus 로고    scopus 로고
    • A contemporary assessment of nocturia: Definition, epidemiology, pathophysiology, and management - A systematic review and meta-analysis
    • J.N. Cornu, P. Abrams, and C.R. Chapple A contemporary assessment of nocturia: definition, epidemiology, pathophysiology, and management - a systematic review and meta-analysis Eur Urol 62 2012 877 890
    • (2012) Eur Urol , vol.62 , pp. 877-890
    • Cornu, J.N.1    Abrams, P.2    Chapple, C.R.3
  • 19
    • 0033305741 scopus 로고    scopus 로고
    • Long-term consequences of castration in men: Lessons from the Skoptzy and the eunuchs of the Chinese and Ottoman courts
    • J.D. Wilson, and C. Roehrborn Long-term consequences of castration in men: lessons from the Skoptzy and the eunuchs of the Chinese and Ottoman courts J Clin Endocrinol Metab 84 1999 4324 4331
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4324-4331
    • Wilson, J.D.1    Roehrborn, C.2
  • 20
    • 0033625134 scopus 로고    scopus 로고
    • Dihydrotestosterone and the concept of 5α-reductase inhibition in human benign prostatic hyperplasia
    • G. Bartsch, R.S. Rittmaster, and H. Klocker Dihydrotestosterone and the concept of 5α-reductase inhibition in human benign prostatic hyperplasia Eur Urol 37 2000 367 380
    • (2000) Eur Urol , vol.37 , pp. 367-380
    • Bartsch, G.1    Rittmaster, R.S.2    Klocker, H.3
  • 21
    • 78651357284 scopus 로고    scopus 로고
    • Estrogen and androgen signaling in the pathogenesis of BPH
    • C.K. Ho, and F.K. Habib Estrogen and androgen signaling in the pathogenesis of BPH Nat Rev Urol 8 2011 29 41
    • (2011) Nat Rev Urol , vol.8 , pp. 29-41
    • Ho, C.K.1    Habib, F.K.2
  • 23
    • 84876947830 scopus 로고    scopus 로고
    • Late-onset hypogonadism syndrome and lower urinary tract symptoms
    • K. Shigehara, and M. Namiki Late-onset hypogonadism syndrome and lower urinary tract symptoms Korean J Urol 52 2011 657 663
    • (2011) Korean J Urol , vol.52 , pp. 657-663
    • Shigehara, K.1    Namiki, M.2
  • 24
    • 77952192447 scopus 로고    scopus 로고
    • Serum sex hormones and the 20-year risk of lower urinary tract symptoms in community-dwelling older men
    • M.D. Trifiro, J.K. Parsons, K. Palazzi-Churas, J. Bergstrom, C. Lakin, and E. Barrett-Connor Serum sex hormones and the 20-year risk of lower urinary tract symptoms in community-dwelling older men BJU Int 105 2009 1554 1559
    • (2009) BJU Int , vol.105 , pp. 1554-1559
    • Trifiro, M.D.1    Parsons, J.K.2    Palazzi-Churas, K.3    Bergstrom, J.4    Lakin, C.5    Barrett-Connor, E.6
  • 25
    • 80052717911 scopus 로고    scopus 로고
    • Urological aspects of the metabolic syndrome
    • J. Hammarsten, and R. Peeker Urological aspects of the metabolic syndrome Nat Rev Urol 8 2011 483 494
    • (2011) Nat Rev Urol , vol.8 , pp. 483-494
    • Hammarsten, J.1    Peeker, R.2
  • 26
    • 80053000072 scopus 로고    scopus 로고
    • Prostate development and growth in benign prostatic hyperplasia
    • B.G. Timms, and L.E. Hofkamp Prostate development and growth in benign prostatic hyperplasia Differentiation 82 2011 173 183
    • (2011) Differentiation , vol.82 , pp. 173-183
    • Timms, B.G.1    Hofkamp, L.E.2
  • 27
    • 79551485468 scopus 로고    scopus 로고
    • Antimuscarinic mechanisms and the overactive detrusor: An update
    • K.-E. Andersson Antimuscarinic mechanisms and the overactive detrusor: an update Eur Urol 59 2011 377 386
    • (2011) Eur Urol , vol.59 , pp. 377-386
    • Andersson, K.-E.1
  • 28
    • 24644510333 scopus 로고    scopus 로고
    • ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells
    • E.C. Wang, J.M. Lee, and W.G. Ruiz ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells J Clin Invest 115 2005 2412 2422
    • (2005) J Clin Invest , vol.115 , pp. 2412-2422
    • Wang, E.C.1    Lee, J.M.2    Ruiz, W.G.3
  • 29
    • 0034905026 scopus 로고    scopus 로고
    • Distribution of P2X(1) and P2X(3) receptors in the rat and human urinary bladder
    • S. Elneil, J.N. Skepper, E.J. Kidd, J.G. Williamson, and D.R. Ferguson Distribution of P2X(1) and P2X(3) receptors in the rat and human urinary bladder Pharmacology 63 2001 120 128
    • (2001) Pharmacology , vol.63 , pp. 120-128
    • Elneil, S.1    Skepper, J.N.2    Kidd, E.J.3    Williamson, J.G.4    Ferguson, D.R.5
  • 30
    • 0034081406 scopus 로고    scopus 로고
    • Distribution of P2X receptors in the urinary bladder and the ureter of the rat
    • H.Y. Lee, M. Bardini, and G. Burnstock Distribution of P2X receptors in the urinary bladder and the ureter of the rat J Urol 163 2000 2002 2007
    • (2000) J Urol , vol.163 , pp. 2002-2007
    • Lee, H.Y.1    Bardini, M.2    Burnstock, G.3
  • 31
    • 0035413364 scopus 로고    scopus 로고
    • P2X3 knock-out mice reveal a major sensory role for urothelially released ATP
    • M. Vlaskovska, L. Kasakov, and W. Rong P2X3 knock-out mice reveal a major sensory role for urothelially released ATP J Neurosci 21 2001 5670 5677
    • (2001) J Neurosci , vol.21 , pp. 5670-5677
    • Vlaskovska, M.1    Kasakov, L.2    Rong, W.3
  • 32
    • 76049111528 scopus 로고    scopus 로고
    • Detrusor myocyte activity and afferent signaling
    • K.E. Andersson Detrusor myocyte activity and afferent signaling Neurourol Urodyn 29 2010 97 106
    • (2010) Neurourol Urodyn , vol.29 , pp. 97-106
    • Andersson, K.E.1
  • 33
    • 79952227050 scopus 로고    scopus 로고
    • Interstitial cells of Cajal in the urinary tract
    • K.D. McCloskey Interstitial cells of Cajal in the urinary tract Handb Exp Pharmacol 2011 2011 233 254
    • (2011) Handb Exp Pharmacol , vol.2011 , pp. 233-254
    • McCloskey, K.D.1
  • 34
    • 80054812510 scopus 로고    scopus 로고
    • Distribution of interstitial cells of Cajal and expression of nitric oxide synthase after experimental bladder outlet obstruction in a rat model of bladder overactivity
    • S.O. Kim, B.S. Oh, and I.Y. Chang Distribution of interstitial cells of Cajal and expression of nitric oxide synthase after experimental bladder outlet obstruction in a rat model of bladder overactivity Neurourol Urodyn 30 2011 1639 1645
    • (2011) Neurourol Urodyn , vol.30 , pp. 1639-1645
    • Kim, S.O.1    Oh, B.S.2    Chang, I.Y.3
  • 35
    • 33645016023 scopus 로고    scopus 로고
    • The functional effects of a c-kit tyrosine inhibitor on guinea-pig and human detrusor
    • S.M. Biers, J.M. Reynard, T. Doore, and A.F. Brading The functional effects of a c-kit tyrosine inhibitor on guinea-pig and human detrusor BJU Int 97 2006 612 616
    • (2006) BJU Int , vol.97 , pp. 612-616
    • Biers, S.M.1    Reynard, J.M.2    Doore, T.3    Brading, A.F.4
  • 36
    • 0032877963 scopus 로고    scopus 로고
    • Comparative morphometric study of bladder detrusor between patients with benign prostatic hyperplasia and controls
    • E. Inui, A. Ochiai, Y. Naya, O. Ukimura, and M. Kojima Comparative morphometric study of bladder detrusor between patients with benign prostatic hyperplasia and controls J Urol 161 1999 827 830
    • (1999) J Urol , vol.161 , pp. 827-830
    • Inui, E.1    Ochiai, A.2    Naya, Y.3    Ukimura, O.4    Kojima, M.5
  • 37
    • 77955466240 scopus 로고    scopus 로고
    • Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction
    • C. Fullhase, R. Soler, C. Gratzke, M. Brodsky, G.J. Christ, and K.E. Andersson Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction J Urol 184 2010 783 789
    • (2010) J Urol , vol.184 , pp. 783-789
    • Fullhase, C.1    Soler, R.2    Gratzke, C.3    Brodsky, M.4    Christ, G.J.5    Andersson, K.E.6
  • 38
    • 77953815930 scopus 로고    scopus 로고
    • Urodynamic evaluation of fesoterodine metabolite, doxazosin and their combination in a rat model of partial urethral obstruction
    • C. Fullhase, R. Soler, C. Gratzke, M. Brodsky, G.J. Christ, and K.E. Andersson Urodynamic evaluation of fesoterodine metabolite, doxazosin and their combination in a rat model of partial urethral obstruction BJU Int 106 2010 287 293
    • (2010) BJU Int , vol.106 , pp. 287-293
    • Fullhase, C.1    Soler, R.2    Gratzke, C.3    Brodsky, M.4    Christ, G.J.5    Andersson, K.E.6
  • 39
    • 33751402605 scopus 로고    scopus 로고
    • The detrusor muscle: An innocent victim of bladder outlet obstruction
    • V. Mirone, C. Imbimbo, N. Longo, and F. Fusco The detrusor muscle: an innocent victim of bladder outlet obstruction Eur Urol 51 2007 57 66
    • (2007) Eur Urol , vol.51 , pp. 57-66
    • Mirone, V.1    Imbimbo, C.2    Longo, N.3    Fusco, F.4
  • 40
    • 78649236033 scopus 로고    scopus 로고
    • Bladder outlet obstruction: Progression from inflammation to fibrosis
    • P.D. Metcalfe, J. Wang, and H. Jiao Bladder outlet obstruction: progression from inflammation to fibrosis BJU Int 106 2010 1686 1694
    • (2010) BJU Int , vol.106 , pp. 1686-1694
    • Metcalfe, P.D.1    Wang, J.2    Jiao, H.3
  • 41
    • 80052076515 scopus 로고    scopus 로고
    • Nerve growth factor in bladder dysfunction: Contributing factor, biomarker, and therapeutic target
    • P. Ochodnicky, C.D. Cruz, N. Yoshimura, and M.C. Michel Nerve growth factor in bladder dysfunction: contributing factor, biomarker, and therapeutic target Neurourol Urodyn 30 2011 1227 1241
    • (2011) Neurourol Urodyn , vol.30 , pp. 1227-1241
    • Ochodnicky, P.1    Cruz, C.D.2    Yoshimura, N.3    Michel, M.C.4
  • 42
    • 0035180080 scopus 로고    scopus 로고
    • Effect of chronic bladder outlet obstruction on blood flow of the rabbit bladder
    • A. Schroder, P. Chichester, and B.A. Kogan Effect of chronic bladder outlet obstruction on blood flow of the rabbit bladder J Urol 165 2001 640 646
    • (2001) J Urol , vol.165 , pp. 640-646
    • Schroder, A.1    Chichester, P.2    Kogan, B.A.3
  • 43
    • 84872139801 scopus 로고    scopus 로고
    • Prophylactic effect of tadalafil on bladder function in a rat model of chronic bladder ischemia
    • M. Nomiya, D.M. Burmeister, and N. Sawada Prophylactic effect of tadalafil on bladder function in a rat model of chronic bladder ischemia J Urol 189 2013 754 761
    • (2013) J Urol , vol.189 , pp. 754-761
    • Nomiya, M.1    Burmeister, D.M.2    Sawada, N.3
  • 44
    • 35148893751 scopus 로고    scopus 로고
    • Rho-kinase and effects of Rho-kinase inhibition on the lower urinary tract
    • G.J. Christ, and K.E. Andersson Rho-kinase and effects of Rho-kinase inhibition on the lower urinary tract Neurourol Urodyn 26 2007 948 954
    • (2007) Neurourol Urodyn , vol.26 , pp. 948-954
    • Christ, G.J.1    Andersson, K.E.2
  • 45
    • 0142025372 scopus 로고    scopus 로고
    • Obstruction-induced changes in urinary bladder smooth muscle contractility: A role for Rho kinase
    • W. Bing, S. Chang, and J.A. Hypolite Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase Am J Physiol Renal Physiol 285 2003 F990 F997
    • (2003) Am J Physiol Renal Physiol , vol.285
    • Bing, W.1    Chang, S.2    Hypolite, J.A.3
  • 46
    • 56249104747 scopus 로고    scopus 로고
    • The relationship between erectile dysfunction and lower urinary tract symptoms and the role of phosphodiesterase type 5 inhibitors
    • T.S. Kohler, and K.T. McVary The relationship between erectile dysfunction and lower urinary tract symptoms and the role of phosphodiesterase type 5 inhibitors Eur Urol 55 2009 38 48
    • (2009) Eur Urol , vol.55 , pp. 38-48
    • Kohler, T.S.1    McVary, K.T.2
  • 48
    • 0037830662 scopus 로고    scopus 로고
    • A quantitative analysis of mRNA expression of alpha 1 and beta-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders
    • M. Nomiya, and O. Yamaguchi A quantitative analysis of mRNA expression of alpha 1 and beta-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders J Urol 170 2003 649 653
    • (2003) J Urol , vol.170 , pp. 649-653
    • Nomiya, M.1    Yamaguchi, O.2
  • 49
    • 12544252613 scopus 로고    scopus 로고
    • Increased contractile response to phenylephrine in detrusor of patients with bladder outlet obstruction: Effect of the alpha1A and alpha1D-adrenergic receptor antagonist tamsulosin
    • K. Bouchelouche, L. Andersen, S. Alvarez, J. Nordling, and P. Bouchelouche Increased contractile response to phenylephrine in detrusor of patients with bladder outlet obstruction: effect of the alpha1A and alpha1D-adrenergic receptor antagonist tamsulosin J Urol 173 2005 657 661
    • (2005) J Urol , vol.173 , pp. 657-661
    • Bouchelouche, K.1    Andersen, L.2    Alvarez, S.3    Nordling, J.4    Bouchelouche, P.5
  • 51
    • 3042637079 scopus 로고    scopus 로고
    • Urinary bladder contraction and relaxation: Physiology and pathophysiology
    • K.E. Andersson, and A. Arner Urinary bladder contraction and relaxation: physiology and pathophysiology Physiol Rev 84 2004 935 986
    • (2004) Physiol Rev , vol.84 , pp. 935-986
    • Andersson, K.E.1    Arner, A.2
  • 52
    • 34247205378 scopus 로고    scopus 로고
    • Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl) amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function
    • T. Takasu, M. Ukai, and S. Sato Effect of (R)-2-(2-aminothiazol-4-yl)-4'- {2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function J Pharmacol Exp Ther 321 2007 642 647
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 642-647
    • Takasu, T.1    Ukai, M.2    Sato, S.3
  • 53
    • 80052071598 scopus 로고    scopus 로고
    • Beta3-adrenoceptors in the rat sacral spinal cord and their functional relevance in micturition under normal conditions and in a model of partial urethral obstruction
    • C. Fullhase, R. Soler, K. Westerling-Andersson, and K.E. Andersson Beta3-adrenoceptors in the rat sacral spinal cord and their functional relevance in micturition under normal conditions and in a model of partial urethral obstruction Neurourol Urodyn 30 2011 1382 1387
    • (2011) Neurourol Urodyn , vol.30 , pp. 1382-1387
    • Fullhase, C.1    Soler, R.2    Westerling-Andersson, K.3    Andersson, K.E.4
  • 54
    • 57749110417 scopus 로고    scopus 로고
    • Urothelial effects of oral agents for overactive bladder
    • K.E. Andersson, C. Fullhase, and R. Soler Urothelial effects of oral agents for overactive bladder Curr Urol Rep 9 2008 459 464
    • (2008) Curr Urol Rep , vol.9 , pp. 459-464
    • Andersson, K.E.1    Fullhase, C.2    Soler, R.3
  • 55
    • 84870769243 scopus 로고    scopus 로고
    • Transient receptor potential channels in bladder function
    • A. Avelino, A. Charrua, and B. Frias Transient receptor potential channels in bladder function Acta Physiol (Oxf) 207 2013 110 122
    • (2013) Acta Physiol (Oxf) , vol.207 , pp. 110-122
    • Avelino, A.1    Charrua, A.2    Frias, B.3
  • 56
    • 35148896423 scopus 로고    scopus 로고
    • Increased expression of transient receptor potential vanilloid subfamily 1 in the bladder predicts the response to intravesical instillations of resiniferatoxin in patients with refractory idiopathic detrusor overactivity
    • H.T. Liu, and H.C. Kuo Increased expression of transient receptor potential vanilloid subfamily 1 in the bladder predicts the response to intravesical instillations of resiniferatoxin in patients with refractory idiopathic detrusor overactivity BJU Int 100 2007 1086 1090
    • (2007) BJU Int , vol.100 , pp. 1086-1090
    • Liu, H.T.1    Kuo, H.C.2
  • 57
    • 34248199887 scopus 로고    scopus 로고
    • The molecular basis of urgency: Regional difference of vanilloid receptor expression in the human urinary bladder
    • discussion 439; discussion 451-3
    • Liu L, Mansfield KJ, Kristiana I, Vaux KJ, Millard RJ, Burcher E. The molecular basis of urgency: regional difference of vanilloid receptor expression in the human urinary bladder. Neurourol Urodyn 2007;26:433-8; discussion 439; discussion 451-3.
    • (2007) Neurourol Urodyn , vol.26 , pp. 433-438
    • Liu, L.1    Mansfield, K.J.2    Kristiana, I.3    Vaux, K.J.4    Millard, R.J.5    Burcher, E.6
  • 58
    • 77957602087 scopus 로고    scopus 로고
    • The role of the transient receptor potential (TRP) superfamily of cation-selective channels in the management of the overactive bladder
    • K.E. Andersson, C. Gratzke, and P. Hedlund The role of the transient receptor potential (TRP) superfamily of cation-selective channels in the management of the overactive bladder BJU Int 106 2010 1114 1127
    • (2010) BJU Int , vol.106 , pp. 1114-1127
    • Andersson, K.E.1    Gratzke, C.2    Hedlund, P.3
  • 59
    • 0030740514 scopus 로고    scopus 로고
    • The perceived effects of smoked cannabis on patients with multiple sclerosis
    • P. Consroe, R. Musty, J. Rein, W. Tillery, and R. Pertwee The perceived effects of smoked cannabis on patients with multiple sclerosis Eur Neurol 38 1997 44 48
    • (1997) Eur Neurol , vol.38 , pp. 44-48
    • Consroe, P.1    Musty, R.2    Rein, J.3    Tillery, W.4    Pertwee, R.5
  • 60
    • 62049084948 scopus 로고    scopus 로고
    • Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder
    • C. Gratzke, T. Streng, and A. Park Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder J Urol 181 2009 1939 1948
    • (2009) J Urol , vol.181 , pp. 1939-1948
    • Gratzke, C.1    Streng, T.2    Park, A.3
  • 61
    • 62049085889 scopus 로고    scopus 로고
    • Differential expression of functional cannabinoid receptors in human bladder detrusor and urothelium
    • V. Tyagi, B.J. Philips, and R. Su Differential expression of functional cannabinoid receptors in human bladder detrusor and urothelium J Urol 181 2009 1932 1938
    • (2009) J Urol , vol.181 , pp. 1932-1938
    • Tyagi, V.1    Philips, B.J.2    Su, R.3
  • 62
    • 79955679078 scopus 로고    scopus 로고
    • Local activation of cannabinoid CB(1) receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents
    • J.S. Walczak, and F. Cervero Local activation of cannabinoid CB(1) receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents Mol Pain 7 2011 31
    • (2011) Mol Pain , vol.7 , pp. 31
    • Walczak, J.S.1    Cervero, F.2
  • 63
    • 82255162759 scopus 로고    scopus 로고
    • Expression of fatty acid amide hydrolase (FAAH) in human, mouse, and rat urinary bladder and effects of FAAH inhibition on bladder function in awake rats
    • F. Strittmatter, G. Gandaglia, and F. Benigni Expression of fatty acid amide hydrolase (FAAH) in human, mouse, and rat urinary bladder and effects of FAAH inhibition on bladder function in awake rats Eur Urol 61 2012 98 106
    • (2012) Eur Urol , vol.61 , pp. 98-106
    • Strittmatter, F.1    Gandaglia, G.2    Benigni, F.3
  • 64
    • 0036718477 scopus 로고    scopus 로고
    • The contractile potency of adenosine triphosphate and ecto-adenosine triphosphatase activity in guinea pig detrusor and detrusor from patients with a stable, unstable or obstructed bladder
    • R.A. Harvey, D.E. Skennerton, D. Newgreen, and C.H. Fry The contractile potency of adenosine triphosphate and ecto-adenosine triphosphatase activity in guinea pig detrusor and detrusor from patients with a stable, unstable or obstructed bladder J Urol 168 2002 1235 1239
    • (2002) J Urol , vol.168 , pp. 1235-1239
    • Harvey, R.A.1    Skennerton, D.E.2    Newgreen, D.3    Fry, C.H.4
  • 65
    • 0035729127 scopus 로고    scopus 로고
    • A quantitative analysis of purinoceptor expression in the bladders of patients with symptomatic outlet obstruction
    • B.A. O'Reilly, A.H. Kosaka, T.K. Chang, A.P. Ford, R. Popert, and S.B. McMahon A quantitative analysis of purinoceptor expression in the bladders of patients with symptomatic outlet obstruction BJU Int 87 2001 617 622
    • (2001) BJU Int , vol.87 , pp. 617-622
    • O'Reilly, B.A.1    Kosaka, A.H.2    Chang, T.K.3    Ford, A.P.4    Popert, R.5    McMahon, S.B.6
  • 66
    • 84855986797 scopus 로고    scopus 로고
    • Purinergic P2X3 heteroreceptors enhance parasympathetic motor drive in isolated porcine detrusor, a reliable model for development of P2X selective blockers for detrusor hyperactivity
    • G. D'Agostino, A.M. Condino, V. Calvi, F. Boschi, L. Gioglio, and A. Barbieri Purinergic P2X3 heteroreceptors enhance parasympathetic motor drive in isolated porcine detrusor, a reliable model for development of P2X selective blockers for detrusor hyperactivity Pharmacol Res 65 2012 129 136
    • (2012) Pharmacol Res , vol.65 , pp. 129-136
    • D'Agostino, G.1    Condino, A.M.2    Calvi, V.3    Boschi, F.4    Gioglio, L.5    Barbieri, A.6
  • 67
    • 84872940957 scopus 로고    scopus 로고
    • The mechanism of action of phosphodiesterase type 5 inhibitors in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia
    • F. Giuliano, S. Uckert, M. Maggi, L. Birder, J. Kissel, and L. Viktrup The mechanism of action of phosphodiesterase type 5 inhibitors in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia Eur Urol 63 2013 506 516
    • (2013) Eur Urol , vol.63 , pp. 506-516
    • Giuliano, F.1    Uckert, S.2    Maggi, M.3    Birder, L.4    Kissel, J.5    Viktrup, L.6
  • 68
    • 0031956895 scopus 로고    scopus 로고
    • Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor
    • J.H. Guh, T.L. Hwang, F.N. Ko, S.C. Chueh, M.K. Lai, and C.M. Teng Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor Mol Pharmacol 53 1998 467 474
    • (1998) Mol Pharmacol , vol.53 , pp. 467-474
    • Guh, J.H.1    Hwang, T.L.2    Ko, F.N.3    Chueh, S.C.4    Lai, M.K.5    Teng, C.M.6
  • 69
    • 77951918078 scopus 로고    scopus 로고
    • Chronic inflammation in the pathogenesis of benign prostatic hyperplasia
    • B. Fibbi, G. Penna, A. Morelli, L. Adorini, and M. Maggi Chronic inflammation in the pathogenesis of benign prostatic hyperplasia Int J Androl 33 2010 475 488
    • (2010) Int J Androl , vol.33 , pp. 475-488
    • Fibbi, B.1    Penna, G.2    Morelli, A.3    Adorini, L.4    Maggi, M.5
  • 70
    • 0037326098 scopus 로고    scopus 로고
    • Distribution of inflammation, pre-malignant lesions, incidental carcinoma in histologically confirmed benign prostatic hyperplasia: A retrospective analysis
    • F. Di Silverio, V. Gentile, and A. De Matteis Distribution of inflammation, pre-malignant lesions, incidental carcinoma in histologically confirmed benign prostatic hyperplasia: a retrospective analysis Eur Urol 43 2003 164 175
    • (2003) Eur Urol , vol.43 , pp. 164-175
    • Di Silverio, F.1    Gentile, V.2    De Matteis, A.3
  • 71
    • 33644823157 scopus 로고    scopus 로고
    • Definition of at-risk patients: Baseline variables
    • discussion 21-2
    • Roehrborn CG. Definition of at-risk patients: baseline variables. BJU Int 2006;97(Suppl 2):7-11; discussion 21-2.
    • (2006) BJU Int , vol.97 , Issue.SUPPL. 2 , pp. 7-11
    • Roehrborn, C.G.1
  • 72
    • 65249104596 scopus 로고    scopus 로고
    • Association of C-reactive protein and lower urinary tract symptoms in men and women: Results from Boston Area Community Health survey
    • V. Kupelian, K.T. McVary, and M.J. Barry Association of C-reactive protein and lower urinary tract symptoms in men and women: results from Boston Area Community Health survey Urology 73 2009 950 957
    • (2009) Urology , vol.73 , pp. 950-957
    • Kupelian, V.1    McVary, K.T.2    Barry, M.J.3
  • 73
    • 84872080376 scopus 로고    scopus 로고
    • Role of inflammation in benign prostatic hyperplasia
    • B. Chughtai, R. Lee, A. Te, and S. Kaplan Role of inflammation in benign prostatic hyperplasia Rev Urol 13 2011 147 150
    • (2011) Rev Urol , vol.13 , pp. 147-150
    • Chughtai, B.1    Lee, R.2    Te, A.3    Kaplan, S.4
  • 74
    • 0025188232 scopus 로고
    • Comparison of the mode of action of prostaglandin E2 (PGE2) and sulprostone, a PGE2-derivative, on the lower urinary tract in healthy women. A urodynamic study
    • B. Schussler Comparison of the mode of action of prostaglandin E2 (PGE2) and sulprostone, a PGE2-derivative, on the lower urinary tract in healthy women. A urodynamic study Urol Res 18 1990 349 352
    • (1990) Urol Res , vol.18 , pp. 349-352
    • Schussler, B.1
  • 75
    • 0028988940 scopus 로고
    • Prostaglandin E2-induced bladder hyperactivity in normal, conscious rats: Involvement of tachykinins?
    • O. Ishizuka, A. Mattiasson, and K.E. Andersson Prostaglandin E2-induced bladder hyperactivity in normal, conscious rats: involvement of tachykinins? J Urol 153 1995 2034 2038
    • (1995) J Urol , vol.153 , pp. 2034-2038
    • Ishizuka, O.1    Mattiasson, A.2    Andersson, K.E.3
  • 76
    • 0030670788 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is expressed in bladder during fetal development and stimulated by outlet obstruction
    • J.M. Park, T. Yang, L.J. Arend, A.M. Smart, J.B. Schnermann, and J.P. Briggs Cyclooxygenase-2 is expressed in bladder during fetal development and stimulated by outlet obstruction Am J Physiol 273 1997 F538 F544
    • (1997) Am J Physiol , vol.273
    • Park, J.M.1    Yang, T.2    Arend, L.J.3    Smart, A.M.4    Schnermann, J.B.5    Briggs, J.P.6
  • 77
    • 0032890990 scopus 로고    scopus 로고
    • Obstruction stimulates COX-2 expression in bladder smooth muscle cells via increased mechanical stretch
    • J.M. Park, T. Yang, and L.J. Arend Obstruction stimulates COX-2 expression in bladder smooth muscle cells via increased mechanical stretch Am J Physiol 276 1999 F129 F136
    • (1999) Am J Physiol , vol.276
    • Park, J.M.1    Yang, T.2    Arend, L.J.3
  • 78
    • 28444490694 scopus 로고    scopus 로고
    • Changes of urinary nerve growth factor and prostaglandins in male patients with overactive bladder symptom
    • J.C. Kim, E.Y. Park, S.H. Hong, S.I. Seo, Y.H. Park, and T.K. Hwang Changes of urinary nerve growth factor and prostaglandins in male patients with overactive bladder symptom Int J Urol 12 2005 875 880
    • (2005) Int J Urol , vol.12 , pp. 875-880
    • Kim, J.C.1    Park, E.Y.2    Hong, S.H.3    Seo, S.I.4    Park, Y.H.5    Hwang, T.K.6
  • 79
    • 33645999348 scopus 로고    scopus 로고
    • Nerve growth factor and prostaglandins in the urine of female patients with overactive bladder
    • discussion 1776
    • Kim JC, Park EY, Seo SI, Park YH, Hwang TK. Nerve growth factor and prostaglandins in the urine of female patients with overactive bladder. J Urol 2006;175:1773-6; discussion 1776.
    • (2006) J Urol , vol.175 , pp. 1773-1776
    • Kim, J.C.1    Park, E.Y.2    Seo, S.I.3    Park, Y.H.4    Hwang, T.K.5
  • 80
    • 84870951537 scopus 로고    scopus 로고
    • Obesity and benign prostatic hyperplasia: Clinical connections, emerging etiological paradigms and future directions
    • J.K. Parsons, A.V. Sarma, K. McVary, and J.T. Wei Obesity and benign prostatic hyperplasia: clinical connections, emerging etiological paradigms and future directions J Urol 189 2013 S102 S106
    • (2013) J Urol , vol.189
    • Parsons, J.K.1    Sarma, A.V.2    McVary, K.3    Wei, J.T.4
  • 81
    • 33745780938 scopus 로고    scopus 로고
    • Metabolic factors associated with benign prostatic hyperplasia
    • J.K. Parsons, H.B. Carter, and A.W. Partin Metabolic factors associated with benign prostatic hyperplasia J Clin Endocrinol Metab 91 2006 2562 2568
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2562-2568
    • Parsons, J.K.1    Carter, H.B.2    Partin, A.W.3
  • 82
    • 0035108041 scopus 로고    scopus 로고
    • Hyperinsulinaemia as a risk factor for developing benign prostatic hyperplasia
    • J. Hammarsten, and B. Hogstedt Hyperinsulinaemia as a risk factor for developing benign prostatic hyperplasia Eur Urol 39 2001 151 158
    • (2001) Eur Urol , vol.39 , pp. 151-158
    • Hammarsten, J.1    Hogstedt, B.2
  • 83
    • 55049091503 scopus 로고    scopus 로고
    • The role of gonadotropin-releasing hormone antagonists for the treatment of benign prostatic hyperplasia
    • H. Lepor The role of gonadotropin-releasing hormone antagonists for the treatment of benign prostatic hyperplasia Rev Urol 8 2006 183 189
    • (2006) Rev Urol , vol.8 , pp. 183-189
    • Lepor, H.1
  • 84
    • 77957726553 scopus 로고    scopus 로고
    • Dose-ranging study of the luteinizing hormone-releasing hormone receptor antagonist cetrorelix pamoate in the treatment of patients with symptomatic benign prostatic hyperplasia
    • F. Debruyne, M. Tzvetkov, S. Altarac, and P.A. Geavlete Dose-ranging study of the luteinizing hormone-releasing hormone receptor antagonist cetrorelix pamoate in the treatment of patients with symptomatic benign prostatic hyperplasia Urology 76 2010 927 933
    • (2010) Urology , vol.76 , pp. 927-933
    • Debruyne, F.1    Tzvetkov, M.2    Altarac, S.3    Geavlete, P.A.4
  • 85
    • 84883829363 scopus 로고    scopus 로고
    • National Institute for Health and Care Excellence Web site
    • NICE: medicines information. National Electronic Library for Medicines News. National Institute for Health and Care Excellence Web site. http://www.nelm.nhs.uk/en/NeLM-Area/News/2009 - -December/08/Phase-III-study- with-cetrorelix-in-benign-prostatic-hyperplasia-does-not-reach-primary-endpoint- /.
    • NICE: Medicines Information. National Electronic Library for Medicines News
  • 86
    • 79751520081 scopus 로고    scopus 로고
    • Androgen replacement therapy contributes to improving lower urinary tract symptoms in patients with hypogonadism and benign prostate hypertrophy: A randomised controlled study
    • K. Shigehara, K. Sugimoto, and H. Konaka Androgen replacement therapy contributes to improving lower urinary tract symptoms in patients with hypogonadism and benign prostate hypertrophy: a randomised controlled study Aging Male 14 2011 53 58
    • (2011) Aging Male , vol.14 , pp. 53-58
    • Shigehara, K.1    Sugimoto, K.2    Konaka, H.3
  • 87
    • 34848839854 scopus 로고    scopus 로고
    • Male lower urinary tract symptoms: Treatment with a-blockers, 5-a-reductase inhibitors, antimuscarinics, or a combination
    • R.A. Appell Male lower urinary tract symptoms: treatment with a-blockers, 5-a-reductase inhibitors, antimuscarinics, or a combination Curr Urol Rep 8 2007 370 372
    • (2007) Curr Urol Rep , vol.8 , pp. 370-372
    • Appell, R.A.1
  • 88
    • 0038286511 scopus 로고    scopus 로고
    • Combination treatment with an alpha-blocker plus an anticholinergic for bladder outlet obstruction: A prospective, randomized, controlled study
    • A. Athanasopoulos, K. Gyftopoulos, K. Giannitsas, J. Fisfis, P. Perimenis, and G. Barbalias Combination treatment with an alpha-blocker plus an anticholinergic for bladder outlet obstruction: a prospective, randomized, controlled study J Urol 169 2003 2253 2256
    • (2003) J Urol , vol.169 , pp. 2253-2256
    • Athanasopoulos, A.1    Gyftopoulos, K.2    Giannitsas, K.3    Fisfis, J.4    Perimenis, P.5    Barbalias, G.6
  • 89
    • 33750969044 scopus 로고    scopus 로고
    • Tolterodine and tamsulosin for treatment of men with lower urinary tract symptoms and overactive bladder: A randomized controlled trial
    • S.A. Kaplan, C.G. Roehrborn, E.S. Rovner, M. Carlsson, T. Bavendam, and Z. Guan Tolterodine and tamsulosin for treatment of men with lower urinary tract symptoms and overactive bladder: a randomized controlled trial JAMA 296 2006 2319 2328
    • (2006) JAMA , vol.296 , pp. 2319-2328
    • Kaplan, S.A.1    Roehrborn, C.G.2    Rovner, E.S.3    Carlsson, M.4    Bavendam, T.5    Guan, Z.6
  • 90
    • 24944527452 scopus 로고    scopus 로고
    • Combination treatment with propiverine hydrochloride plus doxazosin controlled release gastrointestinal therapeutic system formulation for overactive bladder and coexisting benign prostatic obstruction: A prospective, randomized, controlled multicenter study
    • K.S. Lee, M.S. Choo, and D.Y. Kim Combination treatment with propiverine hydrochloride plus doxazosin controlled release gastrointestinal therapeutic system formulation for overactive bladder and coexisting benign prostatic obstruction: a prospective, randomized, controlled multicenter study J Urol 174 2005 1334 1338
    • (2005) J Urol , vol.174 , pp. 1334-1338
    • Lee, K.S.1    Choo, M.S.2    Kim, D.Y.3
  • 91
    • 3042755102 scopus 로고    scopus 로고
    • A comparative syudy of the efficacy and safety of tamsulosin hydrochloride alone and combination of propiverine hydrochloride and tamsulosin hydrochloride in the benign prostatic hypertrophy with pollakisuria and/or urinary incontinence
    • H. Saito, T. Yamada, and H. Oshima A comparative syudy of the efficacy and safety of tamsulosin hydrochloride alone and combination of propiverine hydrochloride and tamsulosin hydrochloride in the benign prostatic hypertrophy with pollakisuria and/or urinary incontinence Jpn J Urol Surg 12 1999 525 536
    • (1999) Jpn J Urol Surg , vol.12 , pp. 525-536
    • Saito, H.1    Yamada, T.2    Oshima, H.3
  • 92
    • 34848824466 scopus 로고    scopus 로고
    • Effects of tamsulosin and extended-release oxybutynin on lower urinary tract symptoms in men [abstract 1638]
    • May 20-25, 2006; Atlanta, GA, USA
    • MacDiarmid S, Chen A, Tu N, Peters KM. Effects of tamsulosin and extended-release oxybutynin on lower urinary tract symptoms in men [abstract 1638]. Presented at: American Urological Association annual meeting; May 20-25, 2006; Atlanta, GA, USA.
    • American Urological Association Annual Meeting
    • Macdiarmid, S.1    Chen, A.2    Tu, N.3    Peters, K.M.4
  • 93
    • 84870560801 scopus 로고    scopus 로고
    • Solifenacin plus tamsulosin combination treatment in men with lower urinary tract symptoms and bladder outlet obstruction: A randomized controlled trial
    • S.A. Kaplan, W. He, W.D. Koltun, J. Cummings, T. Schneider, and A. Fakhoury Solifenacin plus tamsulosin combination treatment in men with lower urinary tract symptoms and bladder outlet obstruction: a randomized controlled trial Eur Urol 63 2013 158 165
    • (2013) Eur Urol , vol.63 , pp. 158-165
    • Kaplan, S.A.1    He, W.2    Koltun, W.D.3    Cummings, J.4    Schneider, T.5    Fakhoury, A.6
  • 94
    • 84867064355 scopus 로고    scopus 로고
    • A multicenter, double-blind, randomized, placebo-controlled trial of the beta3-adrenoceptor agonist solabegron for overactive bladder
    • E.H. Ohlstein, A. von Keitz, and M.C. Michel A multicenter, double-blind, randomized, placebo-controlled trial of the beta3-adrenoceptor agonist solabegron for overactive bladder Eur Urol 62 2012 834 840
    • (2012) Eur Urol , vol.62 , pp. 834-840
    • Ohlstein, E.H.1    Von Keitz, A.2    Michel, M.C.3
  • 95
    • 79956199048 scopus 로고    scopus 로고
    • The efficacy and tolerability of mirabegron in patients with overactive bladder - Results from a European-Australian phase III trial
    • V. Khullar, J. Cambronero, and P. Stroberg The efficacy and tolerability of mirabegron in patients with overactive bladder - results from a European-Australian phase III trial Eur Urol Suppl 10 2011 278 279
    • (2011) Eur Urol Suppl , vol.10 , pp. 278-279
    • Khullar, V.1    Cambronero, J.2    Stroberg, P.3
  • 96
    • 84877914090 scopus 로고    scopus 로고
    • Randomized, multicenter phase II study evaluating the urodynamic safety of Mirabegron in males with lower urinary tract symptoms (LUTS) and bladder outlet obstruction (BOO)
    • V. Nitti, S. Rosenberg, H.D. Mitcheson, W. He, A. Fakhoury, and N. Martin Randomized, multicenter phase II study evaluating the urodynamic safety of Mirabegron in males with lower urinary tract symptoms (LUTS) and bladder outlet obstruction (BOO) J Urol Suppl 187 2012 756
    • (2012) J Urol Suppl , vol.187 , pp. 756
    • Nitti, V.1    Rosenberg, S.2    Mitcheson, H.D.3    He, W.4    Fakhoury, A.5    Martin, N.6
  • 97
    • 79960994565 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitors in the management of non-neurogenic male lower urinary tract symptoms: Critical analysis of current evidence
    • J.I. Martinez-Salamanca, J. Carballido, and I. Eardley Phosphodiesterase type 5 inhibitors in the management of non-neurogenic male lower urinary tract symptoms: critical analysis of current evidence Eur Urol 60 2011 527 535
    • (2011) Eur Urol , vol.60 , pp. 527-535
    • Martinez-Salamanca, J.I.1    Carballido, J.2    Eardley, I.3
  • 98
    • 84859422428 scopus 로고    scopus 로고
    • A systematic review and meta-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with alpha-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia
    • M. Gacci, G. Corona, and M. Salvi A systematic review and meta-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with alpha-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia Eur Urol 61 2012 994 1003
    • (2012) Eur Urol , vol.61 , pp. 994-1003
    • Gacci, M.1    Corona, G.2    Salvi, M.3
  • 99
    • 84864663685 scopus 로고    scopus 로고
    • Effects of flavocoxid, a dual inhibitor of COX and 5-lipoxygenase enzymes, on benign prostatic hyperplasia
    • D. Altavilla, L. Minutoli, and F. Polito Effects of flavocoxid, a dual inhibitor of COX and 5-lipoxygenase enzymes, on benign prostatic hyperplasia Br J Pharmacol 167 2012 95 108
    • (2012) Br J Pharmacol , vol.167 , pp. 95-108
    • Altavilla, D.1    Minutoli, L.2    Polito, F.3
  • 100
    • 9644272488 scopus 로고    scopus 로고
    • Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH)
    • discussion 78-9
    • Di Silverio F, Bosman C, Salvatori M, et al. Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). Eur Urol 2005;47:72-9; discussion 78-9.
    • (2005) Eur Urol , vol.47 , pp. 72-79
    • Di Silverio, F.1    Bosman, C.2    Salvatori, M.3
  • 101
    • 67651102648 scopus 로고    scopus 로고
    • Combination therapy with doxazosin and tenoxicam for the management of lower urinary tract symptoms
    • I. Ozdemir, O. Bozkurt, O. Demir, G. Aslan, and A.A. Esen Combination therapy with doxazosin and tenoxicam for the management of lower urinary tract symptoms Urology 74 2009 431 435
    • (2009) Urology , vol.74 , pp. 431-435
    • Ozdemir, I.1    Bozkurt, O.2    Demir, O.3    Aslan, G.4    Esen, A.A.5
  • 102
    • 79951634976 scopus 로고    scopus 로고
    • Human prostatic urethra expresses vitamin D receptor and responds to vitamin D receptor ligation
    • P. Comeglio, A.K. Chavalmane, and B. Fibbi Human prostatic urethra expresses vitamin D receptor and responds to vitamin D receptor ligation J Endocrinol Invest 33 2010 730 738
    • (2010) J Endocrinol Invest , vol.33 , pp. 730-738
    • Comeglio, P.1    Chavalmane, A.K.2    Fibbi, B.3
  • 103
    • 33947096931 scopus 로고    scopus 로고
    • Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol)
    • L. Adorini, G. Penna, and S. Amuchastegui Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol) J Steroid Biochem Mol Biol 103 2007 689 693
    • (2007) J Steroid Biochem Mol Biol , vol.103 , pp. 689-693
    • Adorini, L.1    Penna, G.2    Amuchastegui, S.3
  • 104
    • 33846950785 scopus 로고    scopus 로고
    • BXL-628, a vitamin D receptor agonist effective in benign prostatic hyperplasia treatment, prevents RhoA activation and inhibits RhoA/Rho kinase signaling in rat and human bladder
    • A. Morelli, L. Vignozzi, and S. Filippi BXL-628, a vitamin D receptor agonist effective in benign prostatic hyperplasia treatment, prevents RhoA activation and inhibits RhoA/Rho kinase signaling in rat and human bladder Prostate 67 2007 234 247
    • (2007) Prostate , vol.67 , pp. 234-247
    • Morelli, A.1    Vignozzi, L.2    Filippi, S.3
  • 105
    • 77951249848 scopus 로고    scopus 로고
    • Vitamin D receptor agonists target static, dynamic, and inflammatory components of benign prostatic hyperplasia
    • L. Adorini, G. Penna, B. Fibbi, and M. Maggi Vitamin D receptor agonists target static, dynamic, and inflammatory components of benign prostatic hyperplasia Ann N Y Acad Sci 1193 2010 146 152
    • (2010) Ann N y Acad Sci , vol.1193 , pp. 146-152
    • Adorini, L.1    Penna, G.2    Fibbi, B.3    Maggi, M.4
  • 106
    • 33746901138 scopus 로고    scopus 로고
    • Effects of a vitamin D(3) analogue in a rat model of bladder outlet obstruction
    • A. Schroder, E. Colli, M. Maggi, and K.E. Andersson Effects of a vitamin D(3) analogue in a rat model of bladder outlet obstruction BJU Int 98 2006 637 642
    • (2006) BJU Int , vol.98 , pp. 637-642
    • Schroder, A.1    Colli, E.2    Maggi, M.3    Andersson, K.E.4
  • 107
    • 84863544214 scopus 로고    scopus 로고
    • Effects on bladder function of combining elocalcitol and tolterodine in rats with outflow obstruction
    • T. Streng, K.E. Andersson, and P. Hedlund Effects on bladder function of combining elocalcitol and tolterodine in rats with outflow obstruction BJU Int 110 2012 E125 E131
    • (2012) BJU Int , vol.110
    • Streng, T.1    Andersson, K.E.2    Hedlund, P.3
  • 108
    • 29044445300 scopus 로고    scopus 로고
    • BXL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: A randomized clinical trial
    • E. Colli, P. Rigatti, and F. Montorsi BXL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: a randomized clinical trial Eur Urol 49 2006 82 86
    • (2006) Eur Urol , vol.49 , pp. 82-86
    • Colli, E.1    Rigatti, P.2    Montorsi, F.3
  • 109
    • 67650669008 scopus 로고    scopus 로고
    • Elocalcitol, a vitamin D3 analog for the potential treatment of benign prostatic hyperplasia, overactive bladder and male infertility
    • A. Tiwari Elocalcitol, a vitamin D3 analog for the potential treatment of benign prostatic hyperplasia, overactive bladder and male infertility IDrugs 12 2009 381 393
    • (2009) IDrugs , vol.12 , pp. 381-393
    • Tiwari, A.1
  • 110
    • 84862987030 scopus 로고    scopus 로고
    • Phase IIb, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to determine effects of elocalcitol in women with overactive bladder and idiopathic detrusor overactivity
    • G.A. Digesu, E. Verdi, L. Cardozo, L. Olivieri, V. Khullar, and E. Colli Phase IIb, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to determine effects of elocalcitol in women with overactive bladder and idiopathic detrusor overactivity Urology 80 2012 48 54
    • (2012) Urology , vol.80 , pp. 48-54
    • Digesu, G.A.1    Verdi, E.2    Cardozo, L.3    Olivieri, L.4    Khullar, V.5    Colli, E.6
  • 111
    • 57149095621 scopus 로고    scopus 로고
    • GRC-6211, a new oral specific TRPV1 antagonist, decreases bladder overactivity and noxious bladder input in cystitis animal models
    • A. Charrua, C.D. Cruz, and S. Narayanan GRC-6211, a new oral specific TRPV1 antagonist, decreases bladder overactivity and noxious bladder input in cystitis animal models J Urol 181 2009 379 386
    • (2009) J Urol , vol.181 , pp. 379-386
    • Charrua, A.1    Cruz, C.D.2    Narayanan, S.3
  • 112
    • 78650479042 scopus 로고    scopus 로고
    • Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis
    • W. Everaerts, X. Zhen, and D. Ghosh Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis Proc Natl Acad Sci U S A 107 2010 19084 19089
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 19084-19089
    • Everaerts, W.1    Zhen, X.2    Ghosh, D.3
  • 113
    • 84883818194 scopus 로고    scopus 로고
    • TRPV1 and TRPV4 antagonists have synergistic effect for treating bladder overactivity in rats
    • A. Charrua, C.D. Cruz, and F. Cruz TRPV1 and TRPV4 antagonists have synergistic effect for treating bladder overactivity in rats Eur Urol Suppl 11 2012 e365
    • (2012) Eur Urol Suppl , vol.11 , pp. 365
    • Charrua, A.1    Cruz, C.D.2    Cruz, F.3
  • 114
    • 4344585483 scopus 로고    scopus 로고
    • An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis
    • C.M. Brady, R. DasGupta, C. Dalton, O.J. Wiseman, K.J. Berkley, and C.J. Fowler An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis Mult Scler 10 2004 425 433
    • (2004) Mult Scler , vol.10 , pp. 425-433
    • Brady, C.M.1    Dasgupta, R.2    Dalton, C.3    Wiseman, O.J.4    Berkley, K.J.5    Fowler, C.J.6
  • 115
    • 33750037938 scopus 로고    scopus 로고
    • The effect of cannabis on urge incontinence in patients with multiple sclerosis: A multicentre, randomised placebo-controlled trial (CAMS-LUTS)
    • R.M. Freeman, O. Adekanmi, M.R. Waterfield, A.E. Waterfield, D. Wright, and J. Zajicek The effect of cannabis on urge incontinence in patients with multiple sclerosis: a multicentre, randomised placebo-controlled trial (CAMS-LUTS) Int Urogynecol J Pelvic Floor Dysfunct 17 2006 636 641
    • (2006) Int Urogynecol J Pelvic Floor Dysfunct , vol.17 , pp. 636-641
    • Freeman, R.M.1    Adekanmi, O.2    Waterfield, M.R.3    Waterfield, A.E.4    Wright, D.5    Zajicek, J.6
  • 116
    • 78349253181 scopus 로고    scopus 로고
    • Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis
    • R.B. Kavia, D. De Ridder, C.S. Constantinescu, C.G. Stott, and C.J. Fowler Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis Mult Scler 16 2010 1349 1359
    • (2010) Mult Scler , vol.16 , pp. 1349-1359
    • Kavia, R.B.1    De Ridder, D.2    Constantinescu, C.S.3    Stott, C.G.4    Fowler, C.J.5
  • 117
    • 84860490635 scopus 로고    scopus 로고
    • Hydroxyfasudil ameliorates bladder dysfunction in male spontaneously hypertensive rats
    • e9-14
    • Inoue S, Saito M, Takenaka A. Hydroxyfasudil ameliorates bladder dysfunction in male spontaneously hypertensive rats. Urology 2012;79:1186 e9-14.
    • (2012) Urology , vol.79 , pp. 1186
    • Inoue, S.1    Saito, M.2    Takenaka, A.3
  • 118
    • 70349754506 scopus 로고    scopus 로고
    • Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: An experimental rat model
    • T. Masago, T. Watanabe, M. Saito, Y. Kinoshita, K. Sato, and I. Miyagawa Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model Int J Urol 16 2009 842 847
    • (2009) Int J Urol , vol.16 , pp. 842-847
    • Masago, T.1    Watanabe, T.2    Saito, M.3    Kinoshita, Y.4    Sato, K.5    Miyagawa, I.6
  • 119
    • 67649999446 scopus 로고    scopus 로고
    • Obstruction alters muscarinic receptor-coupled RhoA/Rho-kinase pathway in the urinary bladder of the rat
    • N. Takahashi, H. Shiomi, and N. Kushida Obstruction alters muscarinic receptor-coupled RhoA/Rho-kinase pathway in the urinary bladder of the rat Neurourol Urodyn 28 2009 257 262
    • (2009) Neurourol Urodyn , vol.28 , pp. 257-262
    • Takahashi, N.1    Shiomi, H.2    Kushida, N.3
  • 120
    • 84871871166 scopus 로고    scopus 로고
    • Modulation of bladder afferent signals in normal and spinal cord-injured rats by purinergic P2X3 and P2X2/3 receptors
    • A. Munoz, G.T. Somogyi, T.B. Boone, A.P. Ford, and C.P. Smith Modulation of bladder afferent signals in normal and spinal cord-injured rats by purinergic P2X3 and P2X2/3 receptors BJU Int 110 2012 E409 E414
    • (2012) BJU Int , vol.110
    • Munoz, A.1    Somogyi, G.T.2    Boone, T.B.3    Ford, A.P.4    Smith, C.P.5
  • 121
    • 4143124477 scopus 로고    scopus 로고
    • Protective effect of an oral endothelin converting enzyme inhibitor on rat detrusor function after outlet obstruction
    • A. Schroder, M. Tajimi, H. Matsumoto, C. Schroder, M. Brands, and K.E. Andersson Protective effect of an oral endothelin converting enzyme inhibitor on rat detrusor function after outlet obstruction J Urol 172 2004 1171 1174
    • (2004) J Urol , vol.172 , pp. 1171-1174
    • Schroder, A.1    Tajimi, M.2    Matsumoto, H.3    Schroder, C.4    Brands, M.5    Andersson, K.E.6
  • 122
    • 74549157758 scopus 로고    scopus 로고
    • NX-1207: A novel investigational drug for the treatment of benign prostatic hyperplasia
    • N. Shore NX-1207: a novel investigational drug for the treatment of benign prostatic hyperplasia Expert Opin Investig Drugs 19 2010 305 310
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 305-310
    • Shore, N.1
  • 124
    • 79953249701 scopus 로고    scopus 로고
    • Phase 1 and 2 studies demonstrate the safety and efficacy of intraprostatic injection of PRX302 for the targeted treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia
    • S.R. Denmeade, B. Egerdie, G. Steinhoff, R. Merchant, R. Abi-Habib, and P. Pommerville Phase 1 and 2 studies demonstrate the safety and efficacy of intraprostatic injection of PRX302 for the targeted treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia Eur Urol 59 2011 747 754
    • (2011) Eur Urol , vol.59 , pp. 747-754
    • Denmeade, S.R.1    Egerdie, B.2    Steinhoff, G.3    Merchant, R.4    Abi-Habib, R.5    Pommerville, P.6
  • 125
    • 80052264107 scopus 로고    scopus 로고
    • Contemporary management of lower urinary tract disease with botulinum toxin A: A systematic review of botox (onabotulinumtoxinA) and dysport (abobotulinumtoxinA)
    • A. Mangera, K.E. Andersson, and A. Apostolidis Contemporary management of lower urinary tract disease with botulinum toxin A: a systematic review of botox (onabotulinumtoxinA) and dysport (abobotulinumtoxinA) Eur Urol 60 2011 784 795
    • (2011) Eur Urol , vol.60 , pp. 784-795
    • Mangera, A.1    Andersson, K.E.2    Apostolidis, A.3
  • 126
    • 44949091513 scopus 로고    scopus 로고
    • Drug insight: Biological effects of botulinum toxin A in the lower urinary tract
    • M.B. Chancellor, C.J. Fowler, and A. Apostolidis Drug insight: biological effects of botulinum toxin A in the lower urinary tract Nat Clin Pract Urol 5 2008 319 328
    • (2008) Nat Clin Pract Urol , vol.5 , pp. 319-328
    • Chancellor, M.B.1    Fowler, C.J.2    Apostolidis, A.3
  • 127
    • 84872981465 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled phase 2 dose-ranging study of onabotulinumtoxinA in men with benign prostatic hyperplasia
    • M. Marberger, E. Chartier-Kastler, and B. Egerdie A randomized double-blind placebo-controlled phase 2 dose-ranging study of onabotulinumtoxinA in men with benign prostatic hyperplasia Eur Urol 63 2013 496 503
    • (2013) Eur Urol , vol.63 , pp. 496-503
    • Marberger, M.1    Chartier-Kastler, E.2    Egerdie, B.3


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