Dietary supplementation with Salvia sahendica attenuates acetylcholinesterase activity and increases mitochondrial transcription factor A and antioxidant proteins in the hippocampus of amyloid beta-injected rats

Journal of Pharmacy and Pharmacology

Volumn 65, Issue 10, 2013, Pages 1555-1562

  Foolad, Forough ^a   Khodagholi, Fariba ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

acetylcholinesterase inhibition; Alzheimer's disease; antioxidant activity; Salvia sahendica; TFAM

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN; CATALASE; HERBACEOUS AGENT; MALATE DEHYDROGENASE; MALONALDEHYDE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NUCLEAR RESPIRATORY FACTOR 1; SALVIA SAHENDICA EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN REGION; COGNITIVE DEFECT; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG ISOLATION; DRUG RESPONSE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME REGULATION; HIPPOCAMPAL CA1 REGION; MALE; NEUROPROTECTION; NONHUMAN; OXIDATION REDUCTION REACTION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; SALVIA; SALVIA SAHENDICA; TRANSCRIPTION INITIATION; UPREGULATION; WESTERN BLOTTING;

ACETYLCHOLINESTERASE INHIBITION; ALZHEIMER'S DISEASE; ANTIOXIDANT ACTIVITY; SALVIA SAHENDICA; TFAM;

ACETYLCHOLINESTERASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CA1 REGION, HIPPOCAMPAL; CHOLINESTERASE INHIBITORS; DIETARY SUPPLEMENTS; LIPID PEROXIDATION; MALE; MICROINJECTIONS; RATS; RATS, WISTAR; SALVIA; TRANSCRIPTION FACTORS;

EID: 84883742380     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12116     Document Type: Article

References (47)

1. Ballard C, et al. Alzheimer's disease. Lancet 2011; 377: 1019-1031.
2. Knobloch M, Mansuy IM,. Dendritic spine loss and synaptic alterations in Alzheimer's disease. Mol Neurobiol 2008; 37: 73-82.
3. Schneider LS,. Treatment of Alzheimer's disease with cholinesterase inhibitors. Clin Geriatr Med 2001; 17: 337-339.
4. Pratico D, Delanty N,. Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease. Am J Med 2000; 109: 577-585.
5. Mozafarian V,. A Dictionary of Iranian Plant Names (Latin English Persian). Tehran: Farhang Mosafer Publication, 1996.
6. Kennedy DO, et al. Effects of cholinesterase inhibiting sage (Salvia officinalis) on mood, anxiety and performance on a psychological stressor battery. Neuropsychopharmacol 2005; 31: 845-852.
7. Tildesley NTJ, et al. Positive modulation of mood and cognitive performance following administration of acute doses of Salvia lavandulaefolia essential oil to healthy young volunteers. Physiol Behav 2005; 83: 699-709.
8. Perry NSL, et al. In-vitro activities of S. lavandulaefolia (Spanish Sage) relevant to treatment of Alzheimer's disease. J Pharm Pharmacol 2001; 53: 1347-1356.
9. Bartram T,. Bartram's Encyclopedia of Herbal Medicine. London: Robinson, 1998.
10. Khodagholi F, Ashabi G,. Dietary supplementation with Salvia sahendica attenuates memory deficits, modulates CREB and its down-stream molecules and decreases apoptosis in amyloid beta-injected rats. Behav Brain Res 2013; 241: 62-69.
11. Shaerzadeh F, et al. Antioxidant and antiglycating activities of Salvia sahendica and its protective effect against oxidative stress in neuron-like PC12 cells. J Nat Med 2011a; 65: 455-465.
12. Paxinos G, Watson CR,. The Rat Brain in Stereotaxic Coordinates, 6th edn. New York: Academic Press, 2007.
13. Ellman GL, et al. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961; 7: 88-95.
14. Bradford M,. A rapid and sensitive method for the quantitation of micro-gram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 1976; 72: 248-254.
15. Clark JB, Nicklas WJ,. The metabolism of rat brain mitochondria. J Biol Chem 1970; 245: 4724-4731.
16. Srere PA,. Methods in Enzymology. New York: Academic Press, 1969.
17. Wang Q, et al. Cross-talk between mitochondrial malate dehydrogenase and the cytochrome bc1 complex. J Biol Chem 2010; 285: 10408-10414.
18. Aebi H,. Catalase in vitro. Methods Enzymol 1984; 105: 121-126.
19. Kakkar P, et al. A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem Biophys 1984; 21: 130-132.
20. Ellman GL,. Tissue sulfhydryl groups. Arch Biochem Biophys 1959; 82: 70-77.
21. Draper HH, Hadley M,. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 1990; 186: 421-431.
22. Hayashi Y, et al. Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice. J Neurosci 2008; 28: 8624-8634.
23. Chasseaud LF,. The role of glutathione and glutathione-S-transferases in the metabolism of chemical carcinogens and other electrophilic agents. Adv Cancer Res 1979; 29: 175-274.
24. Vauzour D, et al. Polyphenols and human health: prevention of disease and mechanisms of action. Nutrients 2010; 2: 1106-1131.
25. Ballard CG, et al. Cholinesterases: roles in the brain during health and disease. Curr Alzheimer Res 2005; 2: 307-318.
26. Coyle JT, et al. Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 1983; 219: 1184-1190.
27. Geula C, Mesulam MM,. Cortical cholinergic fibers in aging and Alzheimer's disease: a morphometric study. Neuroscience 1989; 33: 469-481.
28. Beach TG, et al. The cholinergic deficit coincides with Aβ deposition at the earliest histopathologic stages of Alzheimer disease. J Neuropathol Exp Neurol 2000; 59: 308-313.
29. Orhan I, et al. Antioxidant and anticholinesterase evaluation of selected Turkish Salvia species. Food Chem 2007; 103: 1247-1254.
30. Escames G, et al. Attenuation of cardiac mitochondrial dysfunction by melatonin in septic mice. FEBS J 2007; 274: 2135-2147.
31. Parisi MA, Clayton DA,. Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science 1991; 252: 965-969.
32. Puigserver P, et al. A cold inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998; 92: 829-839.
33. Chen X, Yan SD,. Mitochondrial Aβ: a potential cause of metabolic dysfunction in Alzheimer's Disease. IUBMB Life 2006; 58: 686-694.
34. Nulton-Persson AC, Szweda LI,. Modulation of mitochondrial function by hydrogen peroxide. J Biol Chem 2001; 276: 23357-23361.
35. Tretter L, Adam-Vizi V,. Inhibition of Krebs cycle enzymes by hydrogen peroxide: a key role of a-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress. J Neurosci 2000; 20: 8972-8979.
36. Bubber P, et al. Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Ann Neurol 2005; 57: 695-703.
37. Ji LL, et al. Myocardial aging: antioxidant enzyme systems and related biochemical properties. Am J Physiol Regul Integr Comp Physiol 1991; 261: R386-R392.
38. Papas AM,. Determinants of antioxidant status in humans. Lipids 1996; 31: S77-S82.
39. Calabrese V, et al. NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance. Neurochem Res 2000; 25: 1315-1341.
40. Calabrese V, et al. Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity. Neurochem Res 2001; 26: 739-764.
41. Salehi P, et al. Essential oil composition and antimicrobial activity of Salvia sahendica Boiss & Buhse. in different phenological stage. Iran J Pharm Res 2004; 3 (Suppl. 2): 91.
42. Stadtman ER, Levine RL,. Protein oxidation. Ann N Y Acad Sci 2000; 899: 191-208.
43. Shaerzadeh F, et al. Neuroprotective effect of Salvia sahendica is mediated by restoration of mitochondrial function and inhibition of endoplasmic reticulum stress. Neurochem Res 2011b; 36: 2216-2226.
44. Cuvelier ME, et al. Antioxidative activity and phenolic composition of pilot-plant and commercial extracts of sage and rosemary. J Am Oil Chem Soc 1996; 73: 645-652.
45. Jang S, et al. Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proc Natl Acad Sci U S A 2008; 105: 7534-7539.
46. Ozkan G, et al. Study on chemical composition and biological activities of essential oil and extract from Salvia pisidica. LWT-Food Sci Technol 2010; 43: 186-190.
47. Lee EJ, et al. Luteolin exerts anti-tumor activity through the suppression of epidermal growth factor receptor- mediated pathway in MDA-MB-231ER-negative breast cancer cells. Food Chem Toxicol 2012; 50: 4136-4143