Signaling via TLR2 and TLR4 directly down-regulates T cell effector functions: The regulatory face of danger signals

Frontiers in Immunology

Volumn 4, Issue JUL, 2013, Pages

  Zanin Zhorov, Alexandra ^a   Cohen, Irun R ^b  

^a Kadmon Research Institute   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Direct signaling; HSP60; Inflammation; LPS; T cell inhibition; TLR2; TLR4

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHAPERONIN 60; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; PEPTIDE P2777; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; AUTOIMMUNE DISEASE; CELL PROLIFERATION; CHEMOTAXIS; DIABETES MELLITUS; DOWN REGULATION; EFFECTOR CELL; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; MULTICENTER STUDY (TOPIC); NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PHENOTYPE; SHORT SURVEY; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84883737108     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00211     Document Type: Short Survey

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