Actin dynamics regulated by the balance of neuronal wiskott-aldrich syndrome protein (N-WASP) and cofilin activities determines the biphasic response of glucose-induced insulin secretion

Journal of Biological Chemistry

Volumn 288, Issue 36, 2013, Pages 25851-25864

  Uenishi, Eita ^a,b   Shibasaki, Tadao ^a   Takahashi, Harumi ^a   Seki, Chihiro ^a   Hamaguchi, Hitomi ^a   Yasuda, Takao ^a   Tatebe, Masao ^a   Oiso, Yutaka ^b   Takenawa, Tadaomi ^a   Seino, Susumu ^a,c  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN DYNAMICS; BIPHASIC RESPONSE; COFILIN; F-ACTIN; INSULIN SECRETION; WISKOTT-ALDRICH SYNDROME PROTEINS;

DYNAMICS; GLUCOSE; INSULIN; PHYSIOLOGY;

PROTEINS;

ACTIN; ACTIN RELATED PROTEIN 2-3 COMPLEX; COFILIN; F ACTIN; G ACTIN; GLUCOSE; MUTANT PROTEIN; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN;

ACTIN POLYMERIZATION; ARTICLE; CONTROLLED STUDY; DYNAMICS; GENE SILENCING; INSULIN RELEASE; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

Β-CELL; ACTIN; ACTIN DYNAMICS; BIPHASIC INSULIN SECRETION; CDC42; COFILIN; GLUCOSE-INDUCED INSULIN SECRETION; INSULIN SECRETION; N-WASP;

ACTIN DEPOLYMERIZING FACTORS; ACTIN-RELATED PROTEIN 2-3 COMPLEX; ACTINS; ANIMALS; CELL LINE; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; SWEETENING AGENTS; WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL;

EID: 84883681341     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.464420     Document Type: Article

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