Detection of dihydrofolate reductase conformational change by fret using two fluorescent amino acids

Journal of the American Chemical Society

Volumn 135, Issue 35, 2013, Pages 12924-12927

  Chen, Shengxi ^a   Fahmi, Nour Eddine ^a   Wang, Lin ^b   Bhattacharya, Chandrabali ^a   Benkovic, Stephen J ^b   Hecht, Sidney M ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCENTRATION-DEPENDENT; CONFORMATIONAL CHANGE; DIHYDROFOLATE REDUCTASE; FLUORESCENT SPECIES; LABELED PROTEINS; REACTION COORDINATES; RESONANCE ENERGY TRANSFER; STERIC ACCESSIBILITY;

ENERGY TRANSFER; FLUORESCENCE; FLUOROPHORES;

AMINO ACIDS;

AMINO ACID; DIHYDROFOLATE REDUCTASE; TRIMETHOPRIM;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENERGY TRANSFER; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; IRRADIATION; PROTEIN FOLDING; QUANTUM YIELD; STEREOCHEMISTRY;

AMINO ACIDS; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, MOLECULAR; MOLECULAR STRUCTURE; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84883681327     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja403007r     Document Type: Article

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