Changes in DNA methylation of erythroid-specific genes in K562 cells exposed to phenol and hydroquinone

Toxicology

Volumn 312, Issue 1, 2013, Pages 108-114

  Li, Yang ^a   Wu, Xiao Rong ^a   Li, Xiao Fei ^a   Suriguga, ^a   Yu, Chun Hong ^a   Li, Yi Ran ^a   Yi, Zong Chun ^a  

^a BEIHANG UNIVERSITY   (China)

Author keywords

Benzene metabolites; DNA methylation; Erythroid differentiation; Globin; Heme

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ALPHA GLOBULIN; HEMIN; HEMOGLOBIN; HEMOGLOBIN BETA CHAIN; HYDROQUINONE; PHENOL; PORPHOBILINOGEN DEAMINASE; TRANSCRIPTION FACTOR GATA 1;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN K 562; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ERYTHROID CELL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEMOGLOBIN SYNTHESIS; HUMAN; HUMAN CELL; METABOLITE; PRIORITY JOURNAL;

Δ-AMINOLEVULINATE SYNTHASE 2; 5-AZA-2′-DEOXYCYTIDINE; 5-AZA-CDR; ALAS2; BENZENE METABOLITES; BFU-E; DNA METHYLATION; DNASE I HYPERSENSITIVE SITE; ERYTHROID BURST-FORMING UNIT; ERYTHROID DIFFERENTIATION; GATA BINDING PROTEIN 1 (GLOBIN TRANSCRIPTION FACTOR 1); GATA-1; GLOBIN; HB; HEME; HEMOGLOBIN; HS; LCR; LOCUS CONTROL REGION; MALDI-TOF; MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT; PARP-1; PBGD; PBS; PHOSPHATE BUFFERED SALINE; POLY(ADP-RIBOSE) POLYMERASES-1; PORPHOBILINOGEN DEAMINASE; REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION; RT-PCR; SAP; SHRIMP ALKALINE PHOSPHATASE;

AZACITIDINE; BETA-GLOBINS; CELL DIFFERENTIATION; CPG ISLANDS; DNA METHYLATION; ERYTHROID CELLS; ERYTHROPOIESIS; GAMMA-GLOBINS; GATA1 TRANSCRIPTION FACTOR; HUMANS; HYDROQUINONES; HYDROXYMETHYLBILANE SYNTHASE; K562 CELLS; PHENOL;

EID: 84883674658     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.08.007     Document Type: Article

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