Hypomethylation mediated by decreased DNMTs involves in the activation of proto-oncogene MPL in TK6 cells treated with hydroquinone

Toxicology Letters

Volumn 209, Issue 3, 2012, Pages 239-245

  Liu, Linhua ^a   Ling, Xiaoxuan ^a   Liang, Hairong ^a   Gao, Yuting ^a   Yang, Hui ^a   Shao, Junli ^a   Tang, Huanwen ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

DNA methylation; DNMT; Hydroquinone; MPL; TK6 cells

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; B RAF KINASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HYDROQUINONE; MESSENGER RNA; METHYL CPG BINDING PROTEIN 2; MYC PROTEIN; PROTEIN MYB; THROMBOPOIETIN RECEPTOR;

ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; HUMANS; HYDROQUINONES; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, THROMBOPOIETIN;

EID: 84862793639     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.12.020     Document Type: Article

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