Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Racoma, Ira O ^a   Meisen, Walter Hans ^a   Wang, Qi En ^a   Kaur, Balveen ^a   Wani, Altaf A ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIDINE ORANGE; BECLIN 1; CASPASE; CATHEPSIN B; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN P62; THYMOQUINONE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTE; AUTOPHAGY; CANCER CELL CULTURE; CANCER INHIBITION; CELL ASSAY; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GLIOBLASTOMA; HUMAN; HUMAN CELL; LYSOSOME; PROTEIN EXPRESSION; PROTEIN FUNCTION; TARGET CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BENZOQUINONES; CASPASES; CATHEPSINS; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIOBLASTOMA; HUMANS; INTRACELLULAR MEMBRANES; LYSOSOMES; MODELS, BIOLOGICAL; PERMEABILITY;

EID: 84883648774     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072882     Document Type: Article

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