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Volumn 98, Issue 9, 2013, Pages 1442-1449

Krüppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; BORTEZOMIB; CELL CYCLE PROTEIN; DOXYCYCLINE; KRUPPEL LIKE FACTOR 4; MELPHALAN; PROTEIN P53;

EID: 84883643294     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.066944     Document Type: Article
Times cited : (24)

References (44)
  • 1
    • 47549096256 scopus 로고    scopus 로고
    • Roles of Krupel-like factor 4 in normal homeostasis, cancer and stem cells
    • Evans PM, Liu C. Roles of Krupel-like factor 4 in normal homeostasis, cancer and stem cells. Acta Biochim Biophys Sin (Shanghai). 2008;40(7):554-64.
    • (2008) Acta Biochim Biophys Sin (Shanghai) , vol.40 , Issue.7 , pp. 554-564
    • Evans, P.M.1    Liu, C.2
  • 2
    • 0036340041 scopus 로고    scopus 로고
    • The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
    • Katz JP, Perreault N, Goldstein BG, Lee CS, Labosky PA, Yang VW, et al. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development. 2002;129(11): 2619-28.
    • (2002) Development , vol.129 , Issue.11 , pp. 2619-2628
    • Katz, J.P.1    Perreault, N.2    Goldstein, B.G.3    Lee, C.S.4    Labosky, P.A.5    Yang, V.W.6
  • 4
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126(4):663-76.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 5
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007; 131(5):861-72.
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 6
    • 73349129036 scopus 로고    scopus 로고
    • Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming
    • Wei Z, Yang Y, Zhang P, Andrianakos R, Hasegawa K, Lyu J, et al. Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming. Stem Cells. 2009;27(12): 2969-78.
    • (2009) Stem Cells , vol.27 , Issue.12 , pp. 2969-2978
    • Wei, Z.1    Yang, Y.2    Zhang, P.3    Andrianakos, R.4    Hasegawa, K.5    Lyu, J.6
  • 7
    • 30144442965 scopus 로고    scopus 로고
    • KLF4, p21 and context-dependent opposing forces in cancer
    • Rowland BD, Peeper DS. KLF4, p21 and context-dependent opposing forces in cancer. Nat Rev Cancer. 2005;6(1):11-23.
    • (2005) Nat Rev Cancer , vol.6 , Issue.1 , pp. 11-23
    • Rowland, B.D.1    Peeper, D.S.2
  • 8
    • 30144440248 scopus 로고    scopus 로고
    • The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a contextdependent oncogene
    • Rowland BD, Bernards R, Peeper DS. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a contextdependent oncogene. Nat Cell Biol. 2005;7 (11):1074-82.
    • (2005) Nat Cell Biol , vol.7 , Issue.11 , pp. 1074-1082
    • Rowland, B.D.1    Bernards, R.2    Peeper, D.S.3
  • 9
    • 0034674712 scopus 로고    scopus 로고
    • The gut-enriched Kruppel-like factor (Kruppellike factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
    • Zhang W, Geiman DE, Shields JM, Dang DT, Mahatan CS, Kaestner KH, et al. The gut-enriched Kruppel-like factor (Kruppellike factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J Biol Chem. 2000;275(24):18391-8.
    • (2000) J Biol Chem , vol.275 , Issue.24 , pp. 18391-18398
    • Zhang, W.1    Geiman, D.E.2    Shields, J.M.3    Dang, D.T.4    Mahatan, C.S.5    Kaestner, K.H.6
  • 10
    • 49649101156 scopus 로고    scopus 로고
    • Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells
    • Wei D, Kanai M, Jia Z, Le X, Xie K. Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells. Cancer Res. 2008;68(12):4631-9.
    • (2008) Cancer Res , vol.68 , Issue.12 , pp. 4631-4639
    • Wei, D.1    Kanai, M.2    Jia, Z.3    Le, X.4    Xie, K.5
  • 11
    • 70350539580 scopus 로고    scopus 로고
    • Role for Kruppel-like factor 4 in determining the outcome of p53 response to DNA damage
    • Zhou Q, Hong Y, Zhan Q, Shen Y, Liu Z. Role for Kruppel-like factor 4 in determining the outcome of p53 response to DNA damage. Cancer Res. 2009;69(21): 8284-92.
    • (2009) Cancer Res , vol.69 , Issue.21 , pp. 8284-8292
    • Zhou, Q.1    Hong, Y.2    Zhan, Q.3    Shen, Y.4    Liu, Z.5
  • 12
    • 77956579875 scopus 로고    scopus 로고
    • KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classical Hodgkin lymphoma
    • Guan H, Xie L, Leithauser F, Flossbach L, Moller P, Wirth T, et al. KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classical Hodgkin lymphoma. Blood. 2010;116(9):1469-78.
    • (2010) Blood , vol.116 , Issue.9 , pp. 1469-1478
    • Guan, H.1    Xie, L.2    Leithauser, F.3    Flossbach, L.4    Moller, P.5    Wirth, T.6
  • 13
    • 34548061234 scopus 로고    scopus 로고
    • Decreased expression of Kruppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses
    • Good KL, Tangye SG. Decreased expression of Kruppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses. Proc Natl Acad Sci USA. 2007;104(33):13420-5.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.33 , pp. 13420-13425
    • Good, K.L.1    Tangye, S.G.2
  • 14
    • 40149094715 scopus 로고    scopus 로고
    • Kruppel-like factor 4 regulates B cell number and activationinduced B cell proliferation
    • Klaewsongkram J, Yang Y, Golech S, Katz J, Kaestner KH, Weng NP. Kruppel-like factor 4 regulates B cell number and activationinduced B cell proliferation. J Immunol. 2007;179(7):4679-84.
    • (2007) J Immunol , vol.179 , Issue.7 , pp. 4679-4684
    • Klaewsongkram, J.1    Yang, Y.2    Golech, S.3    Katz, J.4    Kaestner, K.H.5    Weng, N.P.6
  • 16
    • 0028282852 scopus 로고
    • Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma
    • Zhang XG, Gaillard JP, Robillard N, Lu ZY, Gu ZJ, Jourdan M, et al. Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma. Blood. 1994;83(12): 3654-63.
    • (1994) Blood , vol.83 , Issue.12 , pp. 3654-3663
    • Zhang, X.G.1    Gaillard, J.P.2    Robillard, N.3    Lu, Z.Y.4    Gu, Z.J.5    Jourdan, M.6
  • 17
    • 0033971174 scopus 로고    scopus 로고
    • Agonist antigp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors
    • Gu ZJ, Vos JD, Rebouissou C, Jourdan M, Zhang XG, Rossi JF, et al. Agonist antigp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors. Leukemia. 2000;14(1):188-97.
    • (2000) Leukemia , vol.14 , Issue.1 , pp. 188-197
    • Gu, Z.J.1    Vos, J.D.2    Rebouissou, C.3    Jourdan, M.4    Zhang, X.G.5    Rossi, J.F.6
  • 18
    • 0031839962 scopus 로고    scopus 로고
    • A gp130 interleukin-6 transducer-dependent SCID model of human multiple myeloma
    • Rebouissou C, Wijdenes J, Autissier P, Tarte K, Costes V, Liautard J, et al. A gp130 interleukin-6 transducer-dependent SCID model of human multiple myeloma. Blood. 1998;91(12):4727-37.
    • (1998) Blood , vol.91 , Issue.12 , pp. 4727-4737
    • Rebouissou, C.1    Wijdenes, J.2    Autissier, P.3    Tarte, K.4    Costes, V.5    Liautard, J.6
  • 19
    • 79953892192 scopus 로고    scopus 로고
    • A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines
    • Moreaux J, Klein B, Bataille R, Descamps G, Maiga S, Hose D, et al. A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines. Haematologica. 2011;96(4):574-82.
    • (2011) Haematologica , vol.96 , Issue.4 , pp. 574-582
    • Moreaux, J.1    Klein, B.2    Bataille, R.3    Descamps, G.4    Maiga, S.5    Hose, D.6
  • 20
    • 18644386513 scopus 로고    scopus 로고
    • Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays
    • De Vos J, Thykjaer T, Tarte K, Ensslen M, Raynaud P, Requirand G, et al. Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays. Oncogene. 2002;21 (44):6848-57.
    • (2002) Oncogene , vol.21 , Issue.44 , pp. 6848-6857
    • de Vos, J.1    Thykjaer, T.2    Tarte, K.3    Ensslen, M.4    Raynaud, P.5    Requirand, G.6
  • 21
    • 24944584840 scopus 로고    scopus 로고
    • Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics
    • Cremer FW, Bila J, Buck I, Kartal M, Hose D, Ittrich C, et al. Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics. Genes Chromosomes Cancer. 2005;44(2):194-203.
    • (2005) Genes Chromosomes Cancer , vol.44 , Issue.2 , pp. 194-203
    • Cremer, F.W.1    Bila, J.2    Buck, I.3    Kartal, M.4    Hose, D.5    Ittrich, C.6
  • 22
    • 33645504594 scopus 로고    scopus 로고
    • Total therapy 2 without thalidomide in comparison with total therapy 1: Role of intensified induction and posttransplantation consolidation therapies
    • Barlogie B, Tricot G, Rasmussen E, Anaissie E, van Rhee F, Zangari M, et al. Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies. Blood. 2006;107(7):2633-8.
    • (2006) Blood , vol.107 , Issue.7 , pp. 2633-2638
    • Barlogie, B.1    Tricot, G.2    Rasmussen, E.3    Anaissie, E.4    van Rhee, F.5    Zangari, M.6
  • 23
    • 23044512143 scopus 로고    scopus 로고
    • The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature
    • Moreaux J, Cremer FW, Reme T, Raab M, Mahtouk K, Kaukel P, et al. The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature. Blood. 2005;106(3):1021-30.
    • (2005) Blood , vol.106 , Issue.3 , pp. 1021-1030
    • Moreaux, J.1    Cremer, F.W.2    Reme, T.3    Raab, M.4    Mahtouk, K.5    Kaukel, P.6
  • 25
    • 73949109704 scopus 로고    scopus 로고
    • An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization
    • Jourdan M, Caraux A, De Vos J, Fiol G, Larroque M, Cognot C, et al. An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization. Blood. 2009;114(25): 5173-81.
    • (2009) Blood , vol.114 , Issue.25 , pp. 5173-5181
    • Jourdan, M.1    Caraux, A.2    de Vos, J.3    Fiol, G.4    Larroque, M.5    Cognot, C.6
  • 26
    • 84859476869 scopus 로고    scopus 로고
    • Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma
    • Kassambara A, Hose D, Moreaux J, Walker BA, Protopopov A, Rème T, et al. Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma. Haematologica. 2012;97(4):622-30.
    • (2012) Haematologica , vol.97 , Issue.4 , pp. 622-630
    • Kassambara, A.1    Hose, D.2    Moreaux, J.3    Walker, B.A.4    Protopopov, A.5    Rème, T.6
  • 27
    • 16444366375 scopus 로고    scopus 로고
    • Delineation of the roles of paracrine and autocrine interleukin-6 (IL-6) in myeloma cell lines in survival versus cell cycle. A possible model for the cooperation of myeloma cell growth factors
    • Jourdan M, Mahtouk K, Veyrune JL, Couderc G, Fiol G, Redal N, et al. Delineation of the roles of paracrine and autocrine interleukin-6 (IL-6) in myeloma cell lines in survival versus cell cycle. A possible model for the cooperation of myeloma cell growth factors. Eur Cytokine Netw. 2005;16(1):57-64.
    • (2005) Eur Cytokine Netw , vol.16 , Issue.1 , pp. 57-64
    • Jourdan, M.1    Mahtouk, K.2    Veyrune, J.L.3    Couderc, G.4    Fiol, G.5    Redal, N.6
  • 28
    • 43549125507 scopus 로고    scopus 로고
    • A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments
    • Reme T, Hose D, De Vos J, Vassal A, Poulain PO, Pantesco V, et al. A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments. BMC Bioinformatics. 2008;9:16.
    • (2008) BMC Bioinformatics , vol.9 , pp. 16
    • Reme, T.1    Hose, D.2    de Vos, J.3    Vassal, A.4    Poulain, P.O.5    Pantesco, V.6
  • 30
    • 0037276175 scopus 로고    scopus 로고
    • Statistical tests for differential expression in cDNA microarray experiments
    • Cui X, Churchill GA. Statistical tests for differential expression in cDNA microarray experiments. Genome Biol. 2003;4(4):210.
    • (2003) Genome Biol , vol.4 , Issue.4 , pp. 210
    • Cui, X.1    Churchill, G.A.2
  • 32
    • 78650981539 scopus 로고    scopus 로고
    • Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma
    • Hose D, Reme T, Hielscher T, Moreaux J, Messner T, Seckinger A, et al. Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma. Haematologica. 2010;96(1):87-95.
    • (2010) Haematologica , vol.96 , Issue.1 , pp. 87-95
    • Hose, D.1    Reme, T.2    Hielscher, T.3    Moreaux, J.4    Messner, T.5    Seckinger, A.6
  • 33
    • 33748190743 scopus 로고    scopus 로고
    • Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma
    • Walker BA, Leone PE, Jenner MW, Li C, Gonzalez D, Johnson DC, et al. Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma. Blood. 2006;108(5):1733-43.
    • (2006) Blood , vol.108 , Issue.5 , pp. 1733-1743
    • Walker, B.A.1    Leone, P.E.2    Jenner, M.W.3    Li, C.4    Gonzalez, D.5    Johnson, D.C.6
  • 34
    • 0842329848 scopus 로고    scopus 로고
    • Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
    • Zhao W, Hisamuddin IM, Nandan MO, Babbin BA, Lamb NE, Yang VW. Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene. 2004;23(2):395-402.
    • (2004) Oncogene , vol.23 , Issue.2 , pp. 395-402
    • Zhao, W.1    Hisamuddin, I.M.2    Nandan, M.O.3    Babbin, B.A.4    Lamb, N.E.5    Yang, V.W.6
  • 35
    • 70449095895 scopus 로고    scopus 로고
    • Krüppel-like factor 4 mediates histone deacetylase inhibitorinduced prevention of cardiac hypertrophy
    • Kee HJ, Kook H. Krüppel-like factor 4 mediates histone deacetylase inhibitorinduced prevention of cardiac hypertrophy. J Mol Cell Cardiol. 2009;47(6):770-80.
    • (2009) J Mol Cell Cardiol , vol.47 , Issue.6 , pp. 770-780
    • Kee, H.J.1    Kook, H.2
  • 36
    • 84864458523 scopus 로고    scopus 로고
    • Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma
    • Kassambara A, Hose D, Moreaux J, Rème T, Torrent J, Rossi JF, et al. Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma. PLoS ONE. 2012;7(7):e42161.
    • (2012) PLoS ONE , vol.7 , Issue.7
    • Kassambara, A.1    Hose, D.2    Moreaux, J.3    Rème, T.4    Torrent, J.5    Rossi, J.F.6
  • 37
    • 79551665780 scopus 로고    scopus 로고
    • MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
    • Pei H, Zhang L, Luo K, Qin Y, Chesi M, Fei F, et al. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature. 2011;470 (7332):124-8.
    • (2011) Nature , vol.470 , Issue.7332 , pp. 124-128
    • Pei, H.1    Zhang, L.2    Luo, K.3    Qin, Y.4    Chesi, M.5    Fei, F.6
  • 38
    • 84872269688 scopus 로고    scopus 로고
    • Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer
    • Asangani IA, Ateeq B, Cao Q, Dodson L, Pandhi M, Kunju LP, et al. Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer. Mol Cell. 2013;49(1):80-93.
    • (2013) Mol Cell , vol.49 , Issue.1 , pp. 80-93
    • Asangani, I.A.1    Ateeq, B.2    Cao, Q.3    Dodson, L.4    Pandhi, M.5    Kunju, L.P.6
  • 40
    • 79959635260 scopus 로고    scopus 로고
    • DNA interstrand crosslink repair and cancer
    • Deans AJ, West SC. DNA interstrand crosslink repair and cancer. Nat Rev Cancer. 2011;11(7):467-80.
    • (2011) Nat Rev Cancer , vol.11 , Issue.7 , pp. 467-480
    • Deans, A.J.1    West, S.C.2
  • 41
    • 0042093653 scopus 로고    scopus 로고
    • Downregulation and growth inhibitory effect of epithelial-type Krüppel-like transcription factor KLF4, but not KLF5, in bladder cancer. Biochem Biophys Res
    • Ohnishi SS, Ohnami SS, Laub FF, Aoki KK, Suzuki KK, Kanai YY, et al. Downregulation and growth inhibitory effect of epithelial-type Krüppel-like transcription factor KLF4, but not KLF5, in bladder cancer. Biochem Biophys Res. Commun. 2003;308(2):251-6.
    • (2003) Commun , vol.308 , Issue.2 , pp. 251-256
    • Ohnishi, S.S.1    Ohnami, S.S.2    Laub, F.F.3    Aoki, K.K.4    Suzuki, K.K.5    Kanai, Y.Y.6
  • 42
    • 83455218476 scopus 로고    scopus 로고
    • DNA damage responses in cells exposed to sulphur mustard
    • Jowsey PA, Williams FM, Blain PG. DNA damage responses in cells exposed to sulphur mustard. Toxicol Lett. 2012;209(1):1-10.
    • (2012) Toxicol Lett , vol.209 , Issue.1 , pp. 1-10
    • Jowsey, P.A.1    Williams, F.M.2    Blain, P.G.3
  • 43
    • 33144469102 scopus 로고    scopus 로고
    • The proteasome and proteasome inhibitors in cancer therapy
    • Voorhees PM, Orlowski RZ. The proteasome and proteasome inhibitors in cancer therapy. Annu Rev Pharmacol Toxicol. 2006;46:189-213.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 189-213
    • Voorhees, P.M.1    Orlowski, R.Z.2
  • 44
    • 78049501226 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p)
    • Avet-Loiseau H, Leleu X, Roussel M, Moreau P, Guerin-Charbonnel C, Caillot D, et al. Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p). J Clin Oncol. 2010; 28(30):4630-4.
    • (2010) J Clin Oncol , vol.28 , Issue.30 , pp. 4630-4634
    • Avet-Loiseau, H.1    Leleu, X.2    Roussel, M.3    Moreau, P.4    Guerin-Charbonnel, C.5    Caillot, D.6


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