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Volumn 14, Issue 9, 2013, Pages 18256-18268

Neuroprotective effects of α-tocotrienol on kainic acid-induced neurotoxicity in organotypic hippocampal slice cultures

Author keywords

Alpha tocopherol; Alpha tocotrienol; Antioxidant; Kainic acid; Organotypic hippocampal slice culture

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; DICHLOROFLUORESCEIN; KAINIC ACID; LIPID; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TOCOMIN; UNCLASSIFIED DRUG;

EID: 84883607704     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140918256     Document Type: Article
Times cited : (12)

References (38)
  • 1
    • 0037165502 scopus 로고    scopus 로고
    • Preventive effect of melatonin against brain mitochondria DNA damage, lipid peroxidation and seizures induced by kainic acid
    • Mohanan, P.V.; Yamamoto, H.A. Preventive effect of melatonin against brain mitochondria DNA damage, lipid peroxidation and seizures induced by kainic acid. Toxicol. Lett. 2002, 129, 99-105.
    • (2002) Toxicol. Lett , vol.129 , pp. 99-105
    • Mohanan, P.V.1    Yamamoto, H.A.2
  • 2
    • 84888880148 scopus 로고    scopus 로고
    • CCl4 induces tissue-type plasminogen activator in rat brain; protective effects of oregano, rosemary or vitamin
    • doi:10.1016/j.fct.2013.06.049
    • Lavrentiadou S.N.; Tsantarliotou M.P.; Zervos I.A.; Nikolaidis E.; Taitzoglou I.A. CCl4 induces tissue-type plasminogen activator in rat brain; protective effects of oregano, rosemary or vitamin E. Food Chem. Toxicol. 2013, 4, S0278-S6915, doi:10.1016/j.fct.2013.06.049.
    • (2013) E. Food Chem. Toxicol , vol.4
    • Lavrentiadou, S.N.1    Tsantarliotou, M.P.2    Zervos, I.A.3    Nikolaidis, E.4    Taitzoglou, I.A.5
  • 3
    • 0032704101 scopus 로고    scopus 로고
    • Antioxidants, oxidative stress, and degenerative neurological disorders
    • Floyd, R.A. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc. Soc. Exp. Biol. Med. 1999, 222, 236-245.
    • (1999) Proc. Soc. Exp. Biol. Med , vol.222 , pp. 236-245
    • Floyd, R.A.1
  • 4
    • 22844446144 scopus 로고    scopus 로고
    • Protective effect of propofol against kainic acid-induced lipid peroxidation in mouse brain homogenates: Comparison with trolox and melatonin
    • Lee, H.; Jang, Y.H.; Lee, S.R. Protective effect of propofol against kainic acid-induced lipid peroxidation in mouse brain homogenates: Comparison with trolox and melatonin. J. Neurosurg. Anesthesiol. 2005, 17, 144-148.
    • (2005) J. Neurosurg. Anesthesiol , vol.17 , pp. 144-148
    • Lee, H.1    Jang, Y.H.2    Lee, S.R.3
  • 5
    • 80052455223 scopus 로고    scopus 로고
    • Coenzyme Q10 protects neurons against neurotoxicity in hippocampal slice culture
    • Won, R.; Lee, K.H.; Lee, B.H. Coenzyme Q10 protects neurons against neurotoxicity in hippocampal slice culture. Neuroreport 2011, 22, 721-726.
    • (2011) Neuroreport , vol.22 , pp. 721-726
    • Won, R.1    Lee, K.H.2    Lee, B.H.3
  • 6
    • 0024954944 scopus 로고
    • Tocopherol stabilizes membrane against phospholipase A, free fatty acids, and lysophospholipids
    • Kagan, V.E. Tocopherol stabilizes membrane against phospholipase A, free fatty acids, and lysophospholipids. Ann. N. Y. Acad. Sci. 1989, 570, 121-135.
    • (1989) Ann. N. Y. Acad. Sci , vol.570 , pp. 121-135
    • Kagan, V.E.1
  • 7
    • 0027948428 scopus 로고
    • Antioxidant properties of alpha-tocopherol and alpha-tocotrienol
    • Serbinova, E.A.; Packer, L. Antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Meth. Enzymol. 1994, 234, 354-366.
    • (1994) Meth. Enzymol , vol.234 , pp. 354-366
    • Serbinova, E.A.1    Packer, L.2
  • 8
    • 0030949103 scopus 로고    scopus 로고
    • Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin
    • Hosomi, A.; Arita, M.; Sato, Y.; Kiyose, C.; Ueda, T.; Igarashi, O.; Arai, H.; Inoue, K. Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. FEBS Lett. 1997, 409, 105-108.
    • (1997) E Analogs. FEBS Lett , vol.409 , pp. 105-108
    • Hosomi, A.1    Arita, M.2    Sato, Y.3    Kiyose, C.4    Ueda, T.5    Igarashi, O.6    Arai, H.7    Inoue, K.8
  • 9
    • 84856805385 scopus 로고    scopus 로고
    • Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol
    • Uchida T.; Nomura S.; Ichikawa T.; Abe C.; Ikeda S. Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol. J. Nutr. Sci. Vitaminol. 2011, 57, 326-332.
    • (2011) J. Nutr. Sci. Vitaminol , vol.57 , pp. 326-332
    • Uchida, T.1    Nomura, S.2    Ichikawa, T.3    Abe, C.4    Ikeda, S.5
  • 10
    • 0028892443 scopus 로고
    • Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis
    • Tomeo, A.C.; Geller, M.; Watkins, T.R.; Gapor, A.; Bierenbaum, M.L. Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis. Lipids 1995, 30, 1179-1183.
    • (1995) Lipids , vol.30 , pp. 1179-1183
    • Tomeo, A.C.1    Geller, M.2    Watkins, T.R.3    Gapor, A.4    Bierenbaum, M.L.5
  • 11
    • 0027288196 scopus 로고
    • Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    • Parker, R.A.; Pearce, B.C.; Clark, R.W.; Gordon, D.A.; Wright, J.J. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J. Biol. Chem. 1993, 268, 11230-11238.
    • (1993) J. Biol. Chem , vol.268 , pp. 11230-11238
    • Parker, R.A.1    Pearce, B.C.2    Clark, R.W.3    Gordon, D.A.4    Wright, J.J.5
  • 12
    • 0030897729 scopus 로고    scopus 로고
    • Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination
    • Guthrie, N.; Gapor, A.; Chambers, A.F.; Carroll, K.K. Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. J. Nutr. 1997, 127, 544S-548S.
    • (1997) J. Nutr , vol.127
    • Guthrie, N.1    Gapor, A.2    Chambers, A.F.3    Carroll, K.K.4
  • 13
    • 0031744718 scopus 로고    scopus 로고
    • Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status
    • Nesaretnam, K.; Stephen, R.; Dils, R.; Darbre, P. Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status. Lipids 1998, 33, 461-469.
    • (1998) Lipids , vol.33 , pp. 461-469
    • Nesaretnam, K.1    Stephen, R.2    Dils, R.3    Darbre, P.4
  • 14
    • 33646077406 scopus 로고    scopus 로고
    • Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • Numakawa, Y; Numakawa, T.; Matsumoto, T.; Yagasak, I.Y.; Kumamaru, E.; Kunugi, H.; Taguchi, T.; Niki, E. Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. J. Neurochem. 2006, 97, 1191-1202.
    • (2006) J. Neurochem , vol.97 , pp. 1191-1202
    • Numakawa, Y.1    Numakawa, T.2    Matsumoto, T.3    Yagasak, I.Y.4    Kumamaru, E.5    Kunugi, H.6    Taguchi, T.7    Niki, E.8
  • 15
    • 62849099321 scopus 로고    scopus 로고
    • Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats
    • Miyamoto, K.; Shiozaki, M.; Shibata, M.; Koike, M.; Uchiyama, Y.; Gotow, T. Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats. J. Neurosci. Res. 2009, 87, 556-566.
    • (2009) J. Neurosci. Res , vol.87 , pp. 556-566
    • Miyamoto, K.1    Shiozaki, M.2    Shibata, M.3    Koike, M.4    Uchiyama, Y.5    Gotow, T.6
  • 18
    • 78649506908 scopus 로고    scopus 로고
    • Inhibition of hexokinase leads to neuroprotection against excitotoxicity in organotypic hippocampal slice culture
    • Lee, K.H.; Park, J.H.; Won, R.; Lee, H.J.; Nam, T.S.; Lee, B.H. Inhibition of hexokinase leads to neuroprotection against excitotoxicity in organotypic hippocampal slice culture. J. Neurosci. Res. 2011, 89, 96-107.
    • (2011) J. Neurosci. Res , vol.89 , pp. 96-107
    • Lee, K.H.1    Park, J.H.2    Won, R.3    Lee, H.J.4    Nam, T.S.5    Lee, B.H.6
  • 19
    • 0019882992 scopus 로고
    • Kainic acid as a tool for the study of temporal lobe epilepsy
    • Nadler, J.V. Minireview. Kainic acid as a tool for the study of temporal lobe epilepsy. Life Sci. 1981, 29, 2031-2042.
    • (1981) Life Sci , vol.29 , pp. 2031-2042
    • Nadler, J.V.M.1
  • 20
    • 0023735768 scopus 로고
    • Protective effects of mossy fiber lesions against kainic acid-induced seizures and neuronal degeneration
    • Okazaki, M.M.; Nadler, J.V. Protective effects of mossy fiber lesions against kainic acid-induced seizures and neuronal degeneration. Neuroscience 1988, 26, 763-781.
    • (1988) Neuroscience , vol.26 , pp. 763-781
    • Okazaki, M.M.1    Nadler, J.V.2
  • 21
    • 0025860226 scopus 로고
    • Morphological organization of rat hippocampal slice cultures
    • Caeser, M.; Aertsen, A. Morphological organization of rat hippocampal slice cultures. J. Comp. Neurol. 1991, 307, 87-106.
    • (1991) J. Comp. Neurol , vol.307 , pp. 87-106
    • Caeser, M.1    Aertsen, A.2
  • 22
    • 77951499639 scopus 로고    scopus 로고
    • Neuroprotective effects of FK506 against excitotoxicity in organotypic hippocampal slice culture
    • Lee, K.H.; Won, R.; Kim, U.J.; Kim, G.M.; Chung, M.A.; Sohn, J.H.; Lee, B.H. Neuroprotective effects of FK506 against excitotoxicity in organotypic hippocampal slice culture. Neurosci. Lett. 2010, 474, 126-130.
    • (2010) Neurosci. Lett , vol.474 , pp. 126-130
    • Lee, K.H.1    Won, R.2    Kim, U.J.3    Kim, G.M.4    Chung, M.A.5    Sohn, J.H.6    Lee, B.H.7
  • 23
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: From caspases to alternative mechanisms
    • Leist, M.; Jaattela, M. Four deaths and a funeral: From caspases to alternative mechanisms. Nat. Rev. Mol. Cell Biol. 2001, 2, 589-598.
    • (2001) Nat. Rev. Mol. Cell Biol , vol.2 , pp. 589-598
    • Leist, M.1    Jaattela, M.2
  • 25
    • 0024410139 scopus 로고
    • Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats
    • Bromont, C.; Marie, C.; Bralet, J. Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats. Stroke 1989, 20, 918-924.
    • (1989) Stroke , vol.20 , pp. 918-924
    • Bromont, C.1    Marie, C.2    Bralet, J.3
  • 26
    • 34249016295 scopus 로고    scopus 로고
    • Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats
    • Sharma, S.S.; Kaundal, R.K. Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Neurol. Res. 2007, 29, 304-309.
    • (2007) Neurol. Res , vol.29 , pp. 304-309
    • Sharma, S.S.1    Kaundal, R.K.2
  • 27
    • 0345700749 scopus 로고    scopus 로고
    • Iron toxicity in organotypic cultures of hippocampal slices: Role of reactive oxygen species
    • Liu, R.; Liu, W.; Doctrow, S.R.; Baudry, M. Iron toxicity in organotypic cultures of hippocampal slices: Role of reactive oxygen species. J. Neurochem. 2003, 85, 492-502.
    • (2003) J. Neurochem , vol.85 , pp. 492-502
    • Liu, R.1    Liu, W.2    Doctrow, S.R.3    Baudry, M.4
  • 28
    • 0025314212 scopus 로고
    • An evaluation of the anticonvulsant effects of vitamin
    • Levy, S.L.; Burnham, W.M.; Hwang, P.A. An evaluation of the anticonvulsant effects of vitamin E. Epilepsy Res. 1990, 6, 12-17.
    • (1990) E. Epilepsy Res , vol.6 , pp. 12-17
    • Levy, S.L.1    Burnham, W.M.2    Hwang, P.A.3
  • 29
    • 0026665650 scopus 로고
    • The anticonvulsant effects of vitamin E: A further evaluation
    • Levy, S.L.; Burnham, W.M.; Bishai, A.; Hwang, P.A. The anticonvulsant effects of vitamin E: A further evaluation. Can. J. Neurol. Sci. 1992, 19, 201-203.
    • (1992) Can. J. Neurol. Sci , vol.19 , pp. 201-203
    • Levy, S.L.1    Burnham, W.M.2    Bishai, A.3    Hwang, P.A.4
  • 30
    • 0020580167 scopus 로고
    • Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes?
    • Burton, G.W.; Joyce, A.; Ingold, K.U. Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes? Arch. Biochem. Biophys. 1983, 221, 281-290.
    • (1983) Arch. Biochem. Biophys , vol.221 , pp. 281-290
    • Burton, G.W.1    Joyce, A.2    Ingold, K.U.3
  • 32
    • 0025761230 scopus 로고
    • Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol
    • Serbinova, E.; Kagan, V.; Han, D.; Packer, L. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic. Biol. Med. 1991, 10, 263-275.
    • (1991) Free Radic. Biol. Med , vol.10 , pp. 263-275
    • Serbinova, E.1    Kagan, V.2    Han, D.3    Packer, L.4
  • 33
    • 0027525498 scopus 로고
    • Structural and dynamic membrane properties of alpha-tocopherol and alpha-tocotrienol: Implication to the molecular mechanism of their antioxidant potency
    • Suzuki, Y.J.; Tsuchiya, M.; Wassall, S.R.; Choo, Y.M.; Govil, G.; Kagan, V.E.; Packer, L. Structural and dynamic membrane properties of alpha-tocopherol and alpha-tocotrienol: Implication to the molecular mechanism of their antioxidant potency. Biochemistry 1993, 32, 10692-10699.
    • (1993) Biochemistry , vol.32 , pp. 10692-10699
    • Suzuki, Y.J.1    Tsuchiya, M.2    Wassall, S.R.3    Choo, Y.M.4    Govil, G.5    Kagan, V.E.6    Packer, L.7
  • 34
    • 0029144077 scopus 로고
    • Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria
    • Kamat, J.P.; Devasagayam, T.P. Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria. Neurosci. Lett. 1995, 195, 179-182.
    • (1995) Neurosci. Lett , vol.195 , pp. 179-182
    • Kamat, J.P.1    Devasagayam, T.P.2
  • 35
    • 13144307108 scopus 로고    scopus 로고
    • Chemistry and biology of vitamin E
    • Schneider, C. Chemistry and biology of vitamin E. Mol. Nutr. Food Res. 2005, 49, 7-30.
    • (2005) Mol. Nutr. Food Res , vol.49 , pp. 7-30
    • Schneider, C.1
  • 36
    • 0021330425 scopus 로고
    • Inhibition of oxidation of methyl linoleate in solution by vitamin E and vitamin C
    • Niki, E.; Saito, T.; Kawakami, A.; Kamiya, Y. Inhibition of oxidation of methyl linoleate in solution by vitamin E and vitamin C. J. Biol. Chem. 1984, 259, 4177-4182.
    • (1984) J. Biol. Chem , vol.259 , pp. 4177-4182
    • Niki, E.1    Saito, T.2    Kawakami, A.3    Kamiya, Y.4
  • 37
    • 0032818701 scopus 로고    scopus 로고
    • Comparative study on dynamics of antioxidative action of alpha-tocopheryl hydroquinone, ubiquinol, and alpha-tocopherol against lipid peroxidation
    • Shi, H.; Noguchi, N.; Niki, E. Comparative study on dynamics of antioxidative action of alpha-tocopheryl hydroquinone, ubiquinol, and alpha-tocopherol against lipid peroxidation. Free Radic. Biol. Med. 1999, 27, 334-346.
    • (1999) Free Radic. Biol. Med , vol.27 , pp. 334-346
    • Shi, H.1    Noguchi, N.2    Niki, E.3
  • 38
    • 0025805120 scopus 로고
    • Simple method for organotypic cultures of nervous tissue
    • Stoppini, L.; Buchs, P.A.; Muller, D.A. Simple method for organotypic cultures of nervous tissue. J. Neurosci. Methods 1991, 37, 173-182.
    • (1991) J. Neurosci. Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.A.3


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