-
1
-
-
0034721255
-
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
-
Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000; 343: 230
-
(2000)
N Engl J Med
, vol.343
, pp. 230
-
-
Shapiro, A.M.1
Lakey, J.R.2
Ryan, E.A.3
-
2
-
-
10744219939
-
Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody
-
Hering BJ, Kandaswamy R, Harmon JV, et al. Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody. Am J Transplant 2004; 4: 390
-
(2004)
Am J Transplant
, vol.4
, pp. 390
-
-
Hering, B.J.1
Kandaswamy, R.2
Harmon, J.V.3
-
3
-
-
58849101815
-
Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes
-
Froud T, Baidal DA, Faradji R, et al. Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes. Transplantation 2008; 86: 1695
-
(2008)
Transplantation
, vol.86
, pp. 1695
-
-
Froud, T.1
Baidal, D.A.2
Faradji, R.3
-
4
-
-
78650843724
-
Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade
-
Posselt AM, Szot GL, Frassetto LA, et al. Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade. Transplantation 2010; 90: 1595
-
(2010)
Transplantation
, vol.90
, pp. 1595
-
-
Posselt, A.M.1
Szot, G.L.2
Frassetto, L.A.3
-
5
-
-
79957525661
-
Improving efficacy of clinical islet transplantation with iodixanol-based islet purification, thymoglobulin induction, and blockage of IL-1beta and TNF-alpha
-
Matsumoto S, Takita M, Chaussabel D, et al. Improving efficacy of clinical islet transplantation with iodixanol-based islet purification, thymoglobulin induction, and blockage of IL-1beta and TNF-alpha. Cell Transplant 2011; 20: 1641
-
(2011)
Cell Transplant
, vol.20
, pp. 1641
-
-
Matsumoto, S.1
Takita, M.2
Chaussabel, D.3
-
6
-
-
84862892304
-
Improvement in outcomes of clinical islet transplantation: 1999Y2010
-
Barton FB, Rickels MR, Alejandro R, et al. Improvement in outcomes of clinical islet transplantation: 1999Y2010. Diabetes Care 2012; 35: 1436
-
(2012)
Diabetes Care
, vol.35
, pp. 1436
-
-
Barton, F.B.1
Rickels, M.R.2
Alejandro, R.3
-
7
-
-
34247476877
-
Successful islet transplantation to two recipients from a single donor by targeting proinflammatory cytokines in mice
-
Satoh M, Yasunami Y, Matsuoka N, et al. Successful islet transplantation to two recipients from a single donor by targeting proinflammatory cytokines in mice. Transplantation 2007; 83: 1085
-
(2007)
Transplantation
, vol.83
, pp. 1085
-
-
Satoh, M.1
Yasunami, Y.2
Matsuoka, N.3
-
8
-
-
0036094994
-
Human pancreatic islets produce and secrete MCP-1/CCL2: Relevance in human islet transplantation
-
Piemonti L, Leone BE, Nano R, et al. Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation. Diabetes 2002; 51: 55
-
(2002)
Diabetes
, vol.51
, pp. 55
-
-
Piemonti, L.1
Leone, B.E.2
Nano, R.3
-
9
-
-
77949756774
-
High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice
-
Matsuoka N, Itoh T, Watarai H, et al. High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice. J Clin Invest 2010; 120: 735
-
(2010)
J Clin Invest
, vol.120
, pp. 735
-
-
Matsuoka, N.1
Itoh, T.2
Watarai, H.3
-
10
-
-
20044371024
-
Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation
-
Johansson H, Lukinius A, Moberg L, et al. Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation. Diabetes 2005; 54: 1755
-
(2005)
Diabetes
, vol.54
, pp. 1755
-
-
Johansson, H.1
Lukinius, A.2
Moberg, L.3
-
11
-
-
66849132584
-
Innate immunity and heat shock response in islet transplantation
-
Lai Y, Chen C, Linn T. Innate immunity and heat shock response in islet transplantation. Clin Exp Immunol 2009; 157: 1
-
(2009)
Clin Exp Immunol
, vol.157
, pp. 1
-
-
Lai, Y.1
Chen, C.2
Linn, T.3
-
12
-
-
77954155091
-
Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage
-
Alam MU, Harken JA, Knorn AM, et al. Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage. J Immunol 2009; 183: 5728
-
(2009)
J Immunol
, vol.183
, pp. 5728
-
-
Alam, M.U.1
Harken, J.A.2
Knorn, A.M.3
-
13
-
-
58049209834
-
Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
-
Joffre O, Nolte MA, Sporri R, et al. Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev 2009; 227: 234
-
(2009)
Immunol Rev
, vol.227
, pp. 234
-
-
Joffre, O.1
Nolte, M.A.2
Sporri, R.3
-
14
-
-
17644399470
-
Innate immunity and organ transplantation: The potential role of toll-like receptors
-
Andrade CF, Waddell TK, Keshavjee S, et al. Innate immunity and organ transplantation: the potential role of toll-like receptors. Am J Transplant 2005; 5: 969
-
(2005)
Am J Transplant
, vol.5
, pp. 969
-
-
Andrade, C.F.1
Waddell, T.K.2
Keshavjee, S.3
-
15
-
-
34250181271
-
The innate immune system in allograft rejection and tolerance
-
LaRosa DF, Rahman AH, Turka LA. The innate immune system in allograft rejection and tolerance. J Immunol 2007; 178: 7503
-
(2007)
J Immunol
, vol.178
, pp. 7503
-
-
Larosa, D.F.1
Rahman, A.H.2
Turka, L.A.3
-
16
-
-
33750435582
-
NF-kappaB and the immune response
-
Hayden MS,West AP, Ghosh S. NF-kappaB and the immune response. Oncogene 2006; 25: 6758
-
(2006)
Oncogene
, vol.25
, pp. 6758
-
-
Hayden Mswest, A.P.1
Ghosh, S.2
-
17
-
-
25844459154
-
NF-kappaB: Linking inflammation and immunity to cancer development and progression
-
Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 2005; 5: 749
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 749
-
-
Karin, M.1
Greten, F.R.2
-
18
-
-
45549096989
-
NF-kappaB and IRFs on and off in DC
-
Kaisho T, Tanaka T. Turning NF-kappaB and IRFs on and off in DC. Trends Immunol 2008; 29: 329
-
(2008)
Trends Immunol
, vol.29
, pp. 329
-
-
Kaisho, T.1
Tanaka, T.2
-
19
-
-
0037025347
-
Inhibition of tumor necrosis factor-alpha-induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin
-
Ariga A, Namekawa J, Matsumoto N, et al. Inhibition of tumor necrosis factor-alpha-induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin. J Biol Chem 2002; 277: 24625
-
(2002)
J Biol Chem
, vol.277
, pp. 24625
-
-
Ariga, A.1
Namekawa, J.2
Matsumoto, N.3
-
20
-
-
52449131840
-
Inactivation of NF-kappaB components by covalent binding of (-)-dehydroxymethylepoxyquinomicin to specific cysteine residues
-
Yamamoto M, Horie R, Takeiri M, et al. Inactivation of NF-kappaB components by covalent binding of (-)-dehydroxymethylepoxyquinomicin to specific cysteine residues. J Med Chem 2008; 51: 5780
-
(2008)
J Med Chem
, vol.51
, pp. 5780
-
-
Yamamoto, M.1
Horie, R.2
Takeiri, M.3
-
21
-
-
84863044754
-
A novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice
-
Funakoshi T, Yamashita K, Ichikawa N, et al. A novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice. J Crohns Colitis 2012; 6: 215
-
(2012)
J Crohns Colitis
, vol.6
, pp. 215
-
-
Funakoshi, T.1
Yamashita, K.2
Ichikawa, N.3
-
22
-
-
48949096764
-
The novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin, prevents local and remote organ injury following intestinal ischemia/reperfusion in rats
-
Suzuki T, Yamashita K, Jomen W, et al. The novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin, prevents local and remote organ injury following intestinal ischemia/reperfusion in rats. J Surg Res 2008; 149: 69
-
(2008)
J Surg Res
, vol.149
, pp. 69
-
-
Suzuki, T.1
Yamashita, K.2
Jomen, W.3
-
23
-
-
33845947853
-
Control of allograft rejection by applying a novel nuclear factor-kappaB inhibitor, dehydroxymethylepoxyquinomicin
-
Ueki S, Yamashita K, Aoyagi T, et al. Control of allograft rejection by applying a novel nuclear factor-kappaB inhibitor, dehydroxymethylepoxyquinomicin. Transplantation 2006; 82: 1720
-
(2006)
Transplantation
, vol.82
, pp. 1720
-
-
Ueki, S.1
Yamashita, K.2
Aoyagi, T.3
-
24
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
-
Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 2005; 5: 331
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 331
-
-
Lotze, M.T.1
Tracey, K.J.2
-
25
-
-
35748967851
-
High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity
-
Bianchi ME, Manfredi AA. High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol Rev 2007; 220: 35
-
(2007)
Immunol Rev
, vol.220
, pp. 35
-
-
Bianchi, M.E.1
Manfredi, A.A.2
-
26
-
-
43449092909
-
Effects of DHMEQ, a novel nuclear factor-kappaB inhibitor, on beta cell dysfunction in INS-1 cells
-
Saisho Y, Hirose H, Horimai C, et al. Effects of DHMEQ, a novel nuclear factor-kappaB inhibitor, on beta cell dysfunction in INS-1 cells. Endocr J 2008; 55: 433
-
(2008)
Endocr J
, vol.55
, pp. 433
-
-
Saisho, Y.1
Hirose, H.2
Horimai, C.3
-
27
-
-
84883550951
-
Efficacy of DHMEQ, a NF-kB inhibitor, in Islet transplantation: I
-
Kuraya D, Watanabe M, Koshizuka Y, et al. Efficacy of DHMEQ, a NF-kB inhibitor, in Islet transplantation: I. HMGB1 suppression by DHMEQ prevents early islet graft damage. Transplantation 2013; 96: 445
-
(2013)
HMGB1 Suppression by DHMEQ Prevents Early Islet Graft Damage. Transplantation
, vol.96
, pp. 445
-
-
Kuraya, D.1
Watanabe, M.2
Koshizuka, Y.3
-
28
-
-
20444426542
-
Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products
-
Dumitriu IE, Baruah P, Valentinis B, et al. Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products. J Immunol 2005; 174: 7506
-
(2005)
J Immunol
, vol.174
, pp. 7506
-
-
Dumitriu, I.E.1
Baruah, P.2
Valentinis, B.3
-
29
-
-
50849096898
-
Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice
-
Han J, Zhong J, Wei W, et al. Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice. Diabetes 2008; 57: 2118
-
(2008)
Diabetes
, vol.57
, pp. 2118
-
-
Han, J.1
Zhong, J.2
Wei, W.3
-
30
-
-
35349009132
-
Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NFkappaB activation
-
Palumbo R, Galvez BG, Pusterla T, et al. Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NFkappaB activation. J Cell Biol 2007; 179: 33
-
(2007)
J Cell Biol
, vol.179
, pp. 33
-
-
Palumbo, R.1
Galvez, B.G.2
Pusterla, T.3
-
31
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002; 418: 191
-
(2002)
Nature
, vol.418
, pp. 191
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
32
-
-
79551504353
-
Improved intraportal islet transplantation outcome by systemic IKK-beta inhibition: NF-kappaB activity in pancreatic islets depends on oxygen availability
-
Chen C, Moreno R, Samikannu B, et al. Improved intraportal islet transplantation outcome by systemic IKK-beta inhibition: NF-kappaB activity in pancreatic islets depends on oxygen availability. Am J Transplant 2011; 11: 215
-
(2011)
Am J Transplant
, vol.11
, pp. 215
-
-
Chen, C.1
Moreno, R.2
Samikannu, B.3
-
33
-
-
77954072462
-
TLR4 mediates early graft failure after intraportal islet transplantation
-
Gao Q, Ma LL, Gao X, et al. TLR4 mediates early graft failure after intraportal islet transplantation. Am J Transplant 2010; 10: 1588
-
(2010)
Am J Transplant
, vol.10
, pp. 1588
-
-
Gao, Q.1
Ma, L.L.2
Gao, X.3
-
34
-
-
77955921197
-
Donor pretreatment with DHMEQ improves islet transplantation
-
Takahashi T, Matsumoto S, Matsushita M, et al. Donor pretreatment with DHMEQ improves islet transplantation. J Surg Res 2010; 163: e23
-
(2010)
J Surg Res
, vol.163
-
-
Takahashi, T.1
Matsumoto, S.2
Matsushita, M.3
-
35
-
-
22544458771
-
Human dendritic cells: Potent antigen-presenting cells at the crossroads of innate and adaptive immunity
-
Rossi M, Young JW. Human dendritic cells: potent antigen-presenting cells at the crossroads of innate and adaptive immunity. J Immunol 2005; 175: 1373
-
(2005)
J Immunol
, vol.175
, pp. 1373
-
-
Rossi, M.1
Young, J.W.2
-
36
-
-
0035179882
-
Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
-
Jarrossay D, Napolitani G, Colonna M, et al. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur J Immunol 2001; 31: 3388
-
(2001)
Eur J Immunol
, vol.31
, pp. 3388
-
-
Jarrossay, D.1
Napolitani, G.2
Colonna, M.3
-
37
-
-
0037903228
-
Activation of influenza virusspecific CD4+ and CD8+ T cells: A new role for plasmacytoid dendritic cells in adaptive immunity
-
Fonteneau JF, Gilliet M, Larsson M, et al. Activation of influenza virusspecific CD4+ and CD8+ T cells: a new role for plasmacytoid dendritic cells in adaptive immunity. Blood 2003; 101: 3520
-
(2003)
Blood
, vol.101
, pp. 3520
-
-
Fonteneau, J.F.1
Gilliet, M.2
Larsson, M.3
-
38
-
-
77954761223
-
Regulation of human dendritic cells by a novel specific nuclear factor-kappaB inhibitor, dehydroxymethylepoxyquinomicin
-
Shinoda K, Nakagawa K, Kosaka T, et al. Regulation of human dendritic cells by a novel specific nuclear factor-kappaB inhibitor, dehydroxymethylepoxyquinomicin. Hum Immunol 2010; 71: 763
-
(2010)
Hum Immunol
, vol.71
, pp. 763
-
-
Shinoda, K.1
Nakagawa, K.2
Kosaka, T.3
-
39
-
-
72949099237
-
Islet allograft rejection is independent of toll-like receptor signaling in mice
-
Hutton MJ, Westwell-Roper C, Soukhatcheva G, et al. Islet allograft rejection is independent of toll-like receptor signaling in mice. Transplantation 2009; 88: 1075
-
(2009)
Transplantation
, vol.88
, pp. 1075
-
-
Hutton, M.J.1
Westwell-Roper, C.2
Soukhatcheva, G.3
-
40
-
-
3242671837
-
Preparation and biological activities of optically active dehydroxymethylepoxyquinomicin, a novel NF-JB inhibitor
-
Suzuki Y, Sugiyama C, Ohno O, et al. Preparation and biological activities of optically active dehydroxymethylepoxyquinomicin, a novel NF-JB inhibitor. Tetrahedron 2004; 60: 7061
-
(2004)
Tetrahedron
, vol.60
, pp. 7061
-
-
Suzuki, Y.1
Sugiyama, C.2
Ohno, O.3
-
41
-
-
85027939243
-
Dendritic cells conditioned with NK026680 prolong cardiac allograft survival in mice
-
Shibasaki S, Yamashita K, Yanagawa Y, et al. Dendritic cells conditioned with NK026680 prolong cardiac allograft survival in mice. Transplantation 2012; 93: 1229
-
(2012)
Transplantation
, vol.93
, pp. 1229
-
-
Shibasaki, S.1
Yamashita, K.2
Yanagawa, Y.3
-
42
-
-
84859642994
-
Immunomodulatory effect of nuclear factor-kappaB inhibition by dehydroxymethylepoxyquinomicin in combination with donor-specific blood transfusion
-
Goto R, Yamashita K, Aoyagi T, et al. Immunomodulatory effect of nuclear factor-kappaB inhibition by dehydroxymethylepoxyquinomicin in combination with donor-specific blood transfusion. Transplantation 2012; 93: 777
-
(2012)
Transplantation
, vol.93
, pp. 777
-
-
Goto, R.1
Yamashita, K.2
Aoyagi, T.3
-
43
-
-
33747832531
-
New high mobility group box 1 assay system
-
Yamada S, Yakabe K, Ishii J, et al. New high mobility group box 1 assay system. Clin Chim Acta 2006; 372: 173.
-
(2006)
Clin Chim Acta
, vol.372
, pp. 173
-
-
Yamada, S.1
Yakabe, K.2
Ishii, J.3
|