Improved intraportal islet transplantation outcome by systemic IKK-beta inhibition: NF-κB activity in pancreatic islets depends on oxygen availability

American Journal of Transplantation

Volumn 11, Issue 2, 2011, Pages 215-224

  Chen, C ^a   Moreno, R ^a   Samikannu, B ^a   Bretzel, R G ^a   Schmitz, M L ^a   Linn, T ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

engraftment; hypoxia; innate immunity; Islet transplantation; NF kappaB; transplantation efficiency

Indexed keywords

4 (2 AMINOETHYLAMINO) 1,8 DIMETHYLIMIDAZO[1,2 A]QUINOXALINE; CYTOKINE; FLICE INHIBITORY PROTEIN; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL XL; SURVIVIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL HYPOXIA; CONTROLLED STUDY; ENZYME INHIBITION; GENE ACTIVATION; GENE EXPRESSION; GRAFT SURVIVAL; MALE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; OXYGEN CONCENTRATION; PANCREAS ISLET TRANSPLANTATION; PORTAL VEIN; PRIORITY JOURNAL; SWINE;

ANIMALS; ANOXIA; APOPTOSIS; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; GRAFT SURVIVAL; I-KAPPA B KINASE; IMIDAZOLES; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, NUDE; NF-KAPPA B; OXYGEN; PORTAL VEIN; QUINOXALINES; RECOMBINANT PROTEINS; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 79551504353     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2010.03390.x     Document Type: Article

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