메뉴 건너뛰기




Volumn 529, Issue 1, 2013, Pages 16-20

Association of leptin receptor gene Q223R polymorphism on lipid profiles in comparison study between obese and non-obese subjects

Author keywords

Body mass index; Leptin; Leptin receptor; Polymorphism

Indexed keywords

CHOLESTEROL; LEPTIN RECEPTOR; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 84883553357     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.08.003     Document Type: Article
Times cited : (26)

References (36)
  • 1
    • 0037013151 scopus 로고    scopus 로고
    • Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia
    • Allayee H., et al. Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia. Circ. Res. 2002, 90:926-931.
    • (2002) Circ. Res. , vol.90 , pp. 926-931
    • Allayee, H.1
  • 3
    • 67349258284 scopus 로고    scopus 로고
    • LEPR p.Q223R polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients
    • Ben Ali S., et al. LEPR p.Q223R polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients. ARCMED 2009, 40:186-190.
    • (2009) ARCMED , vol.40 , pp. 186-190
    • Ben Ali, S.1
  • 4
    • 80054718263 scopus 로고    scopus 로고
    • Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study
    • Bender N., et al. Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study. PLoS One 2011, 6:1-14.
    • (2011) PLoS One , vol.6 , pp. 1-14
    • Bender, N.1
  • 5
    • 4243372108 scopus 로고    scopus 로고
    • Association of GLN223ARG polymorphism in the leptin receptor gene with serum leptin levels and BMI in postmenopausal Caucasian women
    • Blakemore A.I.F., Lee A.J., Quinton N.D., Ross R.J.M., Eastell R. Association of GLN223ARG polymorphism in the leptin receptor gene with serum leptin levels and BMI in postmenopausal Caucasian women. Int. J. Obes. Relat. Metab. Disorb. 1998, 6:107.
    • (1998) Int. J. Obes. Relat. Metab. Disorb. , vol.6 , pp. 107
    • Blakemore, A.I.F.1    Lee, A.J.2    Quinton, N.D.3    Ross, R.J.M.4    Eastell, R.5
  • 6
    • 84863888278 scopus 로고    scopus 로고
    • Relationship between leptin G2548A and leptin receptor Q223R gene polymorphisms and obesity and metabolic syndrome risk in Tunisian volunteers
    • Boumaiza I., et al. Relationship between leptin G2548A and leptin receptor Q223R gene polymorphisms and obesity and metabolic syndrome risk in Tunisian volunteers. Genet. Test. Mol. Biomarkers 2012, 16:726-733.
    • (2012) Genet. Test. Mol. Biomarkers , vol.16 , pp. 726-733
    • Boumaiza, I.1
  • 7
    • 17744381149 scopus 로고    scopus 로고
    • Association between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study
    • Chagnon Y.C., et al. Association between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study. J. Clin. Endocrinol. Metab. 2000, 85:29-34.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 29-34
    • Chagnon, Y.C.1
  • 8
    • 33746126567 scopus 로고    scopus 로고
    • P.Q223R leptin receptor polymorphism associated with obesity in Brazilian multi-ethnic subjects
    • Duarte S.F., et al. p.Q223R leptin receptor polymorphism associated with obesity in Brazilian multi-ethnic subjects. Am. J. Hum. Biol. 2006, 18:448-453.
    • (2006) Am. J. Hum. Biol. , vol.18 , pp. 448-453
    • Duarte, S.F.1
  • 9
    • 34249666244 scopus 로고    scopus 로고
    • Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women
    • Fairbrother U.L., Tankó L.B., Walley A.J., Christiansen C., Froguel P., Blakemore A.I. Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women. J. Bone Miner. Res. 2007, 22:544-550.
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 544-550
    • Fairbrother, U.L.1    Tankó, L.B.2    Walley, A.J.3    Christiansen, C.4    Froguel, P.5    Blakemore, A.I.6
  • 10
    • 0022371303 scopus 로고
    • Activation of fat liver cytosolic 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase by adenosine 5'-monophosphate
    • Ferrer A., Caelles C., Massot N., Hegardt F.G. Activation of fat liver cytosolic 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase by adenosine 5'-monophosphate. Biochem. Biophys. Res. Commun. 1985, 132:497-504.
    • (1985) Biochem. Biophys. Res. Commun. , vol.132 , pp. 497-504
    • Ferrer, A.1    Caelles, C.2    Massot, N.3    Hegardt, F.G.4
  • 11
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman J.M., Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 1998, 395:763-770.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 12
    • 18644375929 scopus 로고    scopus 로고
    • Association analysis of the Gln223Arg polymorphism in the human leptin receptor gene, and traits related to obesity in Mexican adolescents
    • Guízar-Mendoza J.M., et al. Association analysis of the Gln223Arg polymorphism in the human leptin receptor gene, and traits related to obesity in Mexican adolescents. J. Hum. Hypertens. 2005, 19:341-346.
    • (2005) J. Hum. Hypertens. , vol.19 , pp. 341-346
    • Guízar-Mendoza, J.M.1
  • 13
    • 18344396039 scopus 로고    scopus 로고
    • A meta-analytic investigation of linkage, and association of common leptin receptor (LEPR) polymorphism with body mass index and waist circumference
    • Heo M., et al. A meta-analytic investigation of linkage, and association of common leptin receptor (LEPR) polymorphism with body mass index and waist circumference. Int. J. Obes. Relat. Metab. Disord. 2002, 26:640-646.
    • (2002) Int. J. Obes. Relat. Metab. Disord. , vol.26 , pp. 640-646
    • Heo, M.1
  • 14
    • 0036293591 scopus 로고    scopus 로고
    • Leptin signaling, adiposity, and energy balance
    • Jequier E. Leptin signaling, adiposity, and energy balance. Ann. N. Y. Acad. Sci. 2002, 967:379-388.
    • (2002) Ann. N. Y. Acad. Sci. , vol.967 , pp. 379-388
    • Jequier, E.1
  • 15
    • 0021922908 scopus 로고
    • Serum cholesterol, lecithin-cholesterol acyltransferase, and hepatic hydroxymethylglutaryl coenzyme A reductase activities of lean and obese Zucker rats
    • Lin R.C. Serum cholesterol, lecithin-cholesterol acyltransferase, and hepatic hydroxymethylglutaryl coenzyme A reductase activities of lean and obese Zucker rats. Metabolism 1985, 34:19-24.
    • (1985) Metabolism , vol.34 , pp. 19-24
    • Lin, R.C.1
  • 16
    • 9844266242 scopus 로고    scopus 로고
    • Human leptin receptor gene in obese Japanese subjects: evidence against either obesity-causing mutations or association of sequence variants with obesity
    • Matsuoka N., et al. Human leptin receptor gene in obese Japanese subjects: evidence against either obesity-causing mutations or association of sequence variants with obesity. Diabetologia 1997, 40:1204-1210.
    • (1997) Diabetologia , vol.40 , pp. 1204-1210
    • Matsuoka, N.1
  • 17
    • 0036732501 scopus 로고    scopus 로고
    • Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil
    • Mattevi V.S., Zembrzuki V.M., Hutz M.H. Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil. Int. J. Obes. Relat. Metab. Disord. 2002, 26:1179-1185.
    • (2002) Int. J. Obes. Relat. Metab. Disord. , vol.26 , pp. 1179-1185
    • Mattevi, V.S.1    Zembrzuki, V.M.2    Hutz, M.H.3
  • 18
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentration in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentration in man. Diabetologia 1985, 28:412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 19
    • 33947581477 scopus 로고    scopus 로고
    • LEPR, ADBR3, IRS-1 and 5-HTT genes polymorphism do not associated with obesity
    • Mergen H., Karaaslan C., Mergen M., Deniz Ozsoy E., Ozata M. LEPR, ADBR3, IRS-1 and 5-HTT genes polymorphism do not associated with obesity. Endocr. J. 2007, 54:89-94.
    • (2007) Endocr. J. , vol.54 , pp. 89-94
    • Mergen, H.1    Karaaslan, C.2    Mergen, M.3    Deniz, O.E.4    Ozata, M.5
  • 20
    • 0024284028 scopus 로고    scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1998, 16:1215-1218.
    • (1998) Nucleic Acids Res. , vol.16 , pp. 1215-1218
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 21
    • 0037122766 scopus 로고    scopus 로고
    • Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
    • Minokoshi Y., Kim Y.B., Peroni O.D., Fryer L.G., Carling D., Kahn B.B. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002, 415:339-343.
    • (2002) Nature , vol.415 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.B.2    Peroni, O.D.3    Fryer, L.G.4    Carling, D.5    Kahn, B.B.6
  • 22
    • 0031054698 scopus 로고    scopus 로고
    • Depot and sex-specific differences in human leptin mRNA expression. Implications for the control of regional fat distribution
    • Montague C.T., Prins J.B., Sanders L., Digby J.E., O'Rahilly S. Depot and sex-specific differences in human leptin mRNA expression. Implications for the control of regional fat distribution. Diabetes 1997, 46:342-347.
    • (1997) Diabetes , vol.46 , pp. 342-347
    • Montague, C.T.1    Prins, J.B.2    Sanders, L.3    Digby, J.E.4    O'Rahilly, S.5
  • 23
    • 81755182237 scopus 로고    scopus 로고
    • Association of polymorphisms in leptin receptor gene with obesity and type 2 diabetes in the local population of Coimbatore
    • Murugesan D., Arunachalam T., Ramamurthy V., Subramanian S. Association of polymorphisms in leptin receptor gene with obesity and type 2 diabetes in the local population of Coimbatore. Indian J. Hum. Genet. 2010, 16:72-77.
    • (2010) Indian J. Hum. Genet. , vol.16 , pp. 72-77
    • Murugesan, D.1    Arunachalam, T.2    Ramamurthy, V.3    Subramanian, S.4
  • 24
    • 3042579670 scopus 로고    scopus 로고
    • Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population
    • Ogawa T., et al. Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population. Metabolism 2004, 53:879-885.
    • (2004) Metabolism , vol.53 , pp. 879-885
    • Ogawa, T.1
  • 25
    • 0037044831 scopus 로고    scopus 로고
    • Glucose-dependent regulation of cholesterol ester metabolism in macrophages by insulin and leptin
    • O'Rourke L., Gronning L.M., Yeaman S.J., Shepherd P.R. Glucose-dependent regulation of cholesterol ester metabolism in macrophages by insulin and leptin. J. Biol. Chem. 2002, 277:42557-42562.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42557-42562
    • O'Rourke, L.1    Gronning, L.M.2    Yeaman, S.J.3    Shepherd, P.R.4
  • 26
    • 23444460111 scopus 로고    scopus 로고
    • Genetics of leptin and obesity: a HuGE review
    • Paracchini V., Pedotti P., Taioli E. Genetics of leptin and obesity: a HuGE review. Am. J. Epidemiol. 2005, 162:101-114.
    • (2005) Am. J. Epidemiol. , vol.162 , pp. 101-114
    • Paracchini, V.1    Pedotti, P.2    Taioli, E.3
  • 27
    • 0035073893 scopus 로고    scopus 로고
    • A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women
    • Quinton N.D., Lee A.J., Ross R.J., Eastell R., Blakemore A.I. A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women. Hum. Genet. 2001, 108:233-236.
    • (2001) Hum. Genet. , vol.108 , pp. 233-236
    • Quinton, N.D.1    Lee, A.J.2    Ross, R.J.3    Eastell, R.4    Blakemore, A.I.5
  • 28
    • 50049098131 scopus 로고    scopus 로고
    • Identification of a novel locus for triglyceride on chromosome 1p31-32 in families with premature CAD and MI
    • Seidelman S.B., Li L., Shen G.Q., Topol E.J., Wang Q.K. Identification of a novel locus for triglyceride on chromosome 1p31-32 in families with premature CAD and MI. J. Lipid Res. 2008, 49:1034-1038.
    • (2008) J. Lipid Res. , vol.49 , pp. 1034-1038
    • Seidelman, S.B.1    Li, L.2    Shen, G.Q.3    Topol, E.J.4    Wang, Q.K.5
  • 29
    • 10744223625 scopus 로고    scopus 로고
    • Leptin receptor polymorphism is associated with serum lipid levels and impairment of cholesterol lowering effect by simvastatin in Japanese men
    • Takahashi-Yasuno A., et al. Leptin receptor polymorphism is associated with serum lipid levels and impairment of cholesterol lowering effect by simvastatin in Japanese men. Diabetes Res. Clin. Pract. 2003, 62:169-175.
    • (2003) Diabetes Res. Clin. Pract. , vol.62 , pp. 169-175
    • Takahashi-Yasuno, A.1
  • 30
    • 0030915473 scopus 로고    scopus 로고
    • Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians
    • Thompson D.B., Ravussin E., Bennett P.H., Bogardus C. Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians. Hum. Mol. Genet. 1997, 6:675-679.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 675-679
    • Thompson, D.B.1    Ravussin, E.2    Bennett, P.H.3    Bogardus, C.4
  • 33
    • 0035003854 scopus 로고    scopus 로고
    • Polymorphism in the leptin receptor gene, body composition and fat distribution in overweight and obese women
    • Wauters M., et al. Polymorphism in the leptin receptor gene, body composition and fat distribution in overweight and obese women. Int. J. Obes. 2001, 25:714-720.
    • (2001) Int. J. Obes. , vol.25 , pp. 714-720
    • Wauters, M.1
  • 34
    • 80051799699 scopus 로고
    • Physical status: the use and interpretation anthropometry. Report of a WHO Expert Committee
    • WHO, Geneva
    • World Health Organization Physical status: the use and interpretation anthropometry. Report of a WHO Expert Committee. WHO Technical Report Series, no. 854 1995, 321-344. WHO, Geneva.
    • (1995) WHO Technical Report Series, no. 854 , pp. 321-344
    • World Health Organization1
  • 35
    • 0034847530 scopus 로고    scopus 로고
    • The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability
    • Yiannakouris N., Yannakoulia M., Melistas L., Chan J.L., Klimis-Zacas D., Mantzoros C. The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability. J. Clin. Endocrinol. Metab. 2001, 86:4434-4439.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4434-4439
    • Yiannakouris, N.1    Yannakoulia, M.2    Melistas, L.3    Chan, J.L.4    Klimis-Zacas, D.5    Mantzoros, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.