Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows

Environmental Science and Technology

Volumn 47, Issue 17, 2013, Pages 10012-10021

  Noyes, Pamela D ^a   Lema, Sean C ^b   Macaulay, Laura J ^a   Douglas, Nora K ^a   Stapleton, Heather M ^a  

^a DUKE UNIVERSITY   (United States)

^b CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECABROMODIPHENYL ETHERS (BDE209); DIETARY EXPOSURE; LOW-LEVEL EXPOSURE; MRNA EXPRESSION; NEURODEVELOPMENT; NON-LINEAR RELATIONSHIPS; POLYBROMINATED DIPHENYL ETHERS; THYROID HORMONES;

BRAIN; FLAME RETARDANTS; GENE EXPRESSION; ORGANIC POLLUTANTS;

HORMONES;

FLAME RETARDANT; LIOTHYRONINE; MESSENGER RNA; POLYBROMINATED DIPHENYL ETHER; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROXINE;

DEVELOPMENTAL BIOLOGY; DOSE-RESPONSE RELATIONSHIP; ETHER; FISH; GENE EXPRESSION; HORMONE; PBDE; POLLUTION EFFECT; POLLUTION EXPOSURE; SIGNALING;

ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; EXPOSURE; MALE; NONHUMAN; PIMEPHALES PROMELAS; PROTEIN EXPRESSION; THYROID GLAND;

ANIMALS; BODY COMPOSITION; BRAIN; CYPRINIDAE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; FISH PROTEINS; FLAME RETARDANTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE EXPRESSION REGULATION; HALOGENATED DIPHENYL ETHERS; IODIDE PEROXIDASE; LIVER; MALE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RANDOM ALLOCATION; RECEPTORS, THYROID HORMONE; REPRODUCTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; THYROID HORMONES; WATER POLLUTANTS, CHEMICAL;

EID: 84883529274     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es402650x     Document Type: Article

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