Impaired oligodendroglial development by decabromodiphenyl ether in rat offspring after maternal exposure from mid-gestation through lactation

Reproductive Toxicology

Volumn 31, Issue 1, 2011, Pages 86-94

  Fujimoto, Hitoshi ^a   Woo, Gye Hyeong ^a   Inoue, Kaoru ^a   Takahashi, Miwa ^a   Hirose, Masao ^c   Nishikawa, Akiyoshi ^a   Shibutani, Makoto ^a,b  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^c Food Safety Commission of Japan   (Japan)

Author keywords

Brominated flame retardants (BFRs); Decabromodiphenyl ether (DBDE); Developmental toxicity; Hypothyroidism; Impaired brain development; Maternal exposure; Rat; White matter hypoplasia

Indexed keywords

DECABROMOBIPHENYL; INDUSTRIAL CHEMICAL; LIOTHYRONINE; THYROXINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MALFORMATION; CELL DENSITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORPUS CALLOSUM; ENVIRONMENTAL EXPOSURE; ESTRUS CYCLE; FEMALE; GESTATIONAL AGE; HISTOPATHOLOGY; HYPOTHYROIDISM; LACTATION; LIVER HYPERTROPHY; LIVER WEIGHT; MALE; MATERNAL NUTRITION; MORPHOMETRICS; NERVE CELL DIFFERENTIATION; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PRENATAL EXPOSURE; PUBERTY; RAT; SPRAGUE DAWLEY RAT; THYROXINE BLOOD LEVEL;

ADMINISTRATION, ORAL; ANIMAL FEED; ANIMALS; CORPUS CALLOSUM; DIET; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; FLAME RETARDANTS; GYRUS CINGULI; HALOGENATED DIPHENYL ETHERS; LACTATION; LIVER; MATERNAL EXPOSURE; OLIGODENDROGLIA; ORGAN SIZE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; THYROID GLAND; THYROID HORMONES;

RATTUS;

EID: 79551597941     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2010.09.003     Document Type: Article

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