Adipogenic potential in human mesenchymal stem cells strictly depends on adult or foetal tissue harvest

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 11, 2013, Pages 2456-2466

  Ragni, Enrico ^a   Viganò, Mariele ^a   Parazzi, Valentina ^a   Montemurro, Tiziana ^a   Montelatici, Elisa ^a   Lavazza, Cristiana ^a   Budelli, Silvia ^a   Vecchini, Alba ^b   Rebulla, Paolo ^a   Giordano, Rosaria ^a   Lazzari, Lorenza ^a  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Adipogenesis; Mesenchymal stem cells; mRNA; Regenerative medicine; Transcription factor

Indexed keywords

ADIPONECTIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; EARLY GROWTH RESPONSE FACTOR 2; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 2; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 5; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 7 LIKE 2; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR HES 1; WNT10B PROTEIN; WNT3A PROTEIN; MESSENGER RNA;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE DERIVED STEM CELL; ADIPOSE TISSUE; AMNION FLUID; ARTICLE; BONE DEVELOPMENT; BONE MARROW; CARTILAGE CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL STRUCTURE; CELL THERAPY; CHONDROGENESIS; FETUS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; MESENCHYMAL STEM CELL; NORMAL HUMAN; OSTEOCYTE; PHENOTYPIC PLASTICITY; PROADIPOCYTE; PROTEIN PHOSPHORYLATION; REGENERATIVE MEDICINE; SIGNAL TRANSDUCTION; SURGICAL TECHNIQUE; TISSUE ENGINEERING; TISSUE REGENERATION; TRANSACTIVATION; UMBILICAL CORD; UMBILICAL CORD BLOOD; ADULT; ADULT STEM CELL; BLOOD VESSEL; CYTOLOGY; FETAL STEM CELL; FETUS BLOOD; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PHENOTYPE; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSPLANTATION;

ADIPOGENESIS; ADIPOSE TISSUE; ADULT; ADULT STEM CELLS; BLOOD VESSELS; FETAL BLOOD; FETAL STEM CELLS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STROMAL CELLS; PHENOTYPE; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE AND ORGAN HARVESTING; TRANSCRIPTION, GENETIC;

EID: 84883526244     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.07.024     Document Type: Article

References (49)

1. J.T. Ayala-Sumuano, C. Velez-Delvalle, A. Beltrán-Langarica, M. Marsch-Moreno, J. Cerbón-Solorzano, and W. Kuri-Harcuch Srebf1a is a key regulator of transcriptional control for adipogenesis Scientific Reports 1 2011 178
2. S.D. Ayers, K.L. Nedrow, R.E. Gillilan, and N. Noy Continuous nucleocytoplasmic shuttling underlies transcriptional activation of PPARgamma by FABP4 Biochemistry 46 2007 6744 6752 (Pubitemid 46906405)
3. K. Birsoy, Z. Chen, and J. Friedman Transcriptional regulation of adipogenesis by KLF4 Cell Metabolism 7 2008 339 347 (Pubitemid 351455215)
4. P. Bossolasco, T. Montemurro, L. Cova, S. Zangrossi, C. Calzarossa, and S. Buiatiotis Molecular and phenotypic characterization of human amniotic fluid cells and their differentiation potential Cell Research 16 2006 329 336
5. M. Breitbach, T. Bostani, W. Roell, Y. Xia, O. Dewald, and J.M. Nygren Potential risks of bone marrow cell transplantation into infarcted hearts Blood 110 2007 1362 1369 (Pubitemid 47281438)
6. Z. Cao, R.M. Umek, and S.L. McKnight Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells Genes and Development 5 1991 1538 1552 (Pubitemid 21906060)
7. P. Carmona-Saez, M. Chagoyen, F. Tirado, J.M. Carazo, and A. Pascual-Montano GENECODIS. A web-based tool for finding significant concurrent annotations in gene lists Genome Biology 8 2007 R3
8. Z. Chen, J.I. Torrens, A. Anand, B.M. Spiegelman, and J.M. Friedman Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms Cell Metabolism 1 2005 93 106 (Pubitemid 43960592)
9. D.C. Ding, W.C. Shyu, and S.Z. Lin Mesenchymal stem cells Cell Transplantation 20 2011 5 14
10. M. Dominici, J.K. Le Blanc, I. Mueller, I. Slaper-Cortenbach, F. Marini, and D. Krause Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Cytotherapy 8 2006 315 317 (Pubitemid 44269669)
11. A. Erices, P. Conget, and J.J. Minguell Mesenchymal progenitor cells in human umbilical cord blood British Journal of Haematology 109 2000 235 242 (Pubitemid 30340601)
12. C.Y. Fong, M. Richards, N. Manasi, A. Biswas, and A. Bongso Comparative growth behaviour and characterization of stem cells from human Wharton's jelly Reproductive BioMedicine Online 15 2007 708 718 (Pubitemid 350285987)
13. E. Hu, J.B. Kim, P. Sarraf, and B.M. Spiegelman Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma Science 274 1996 2100 2103 (Pubitemid 27020707)
14. R. Ikeda, S. Tsukahara, and K. Yoshida Gene expression changes during the chondrogenic differentiation of human mesenchymal stem cells Journal of Biological Sciences 7 2007 729 736 (Pubitemid 47527944)
15. T. Itoh, L. Fairall, K. Amin, Y. Inaba, A. Szanto, and B.L. Balint Structural basis for the activation of PPARgamma by oxidized fatty acids Nature Structural and Molecular Biology 15 2008 924 931
16. D.J. Klemm, J.W. Leitner, P. Watson, A. Nesterova, J.E. Reusch, and M.L. Goalstone Insulin-induced adipocyte differentiation: activation of CREB rescues adipogenesis from the arrest caused by inhibition of prenylation The Journal of Biological Chemistry 276 2001 28430 28435
17. L. Jackson, D. Jones, P. Scotting, and V. Sottile Adult mesenchymal stem cells: differentiation potential and therapeutic applications Journal of Postgraduate Medicine 53 2007 121 127 (Pubitemid 46808816)
18. E. Jing, S. Gesta, and C.R. Kahn SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation Cell Metabolism 6 2007 105 114 (Pubitemid 47163621)
19. M. Kassem, and B.M. Abdallah Human bone-marrow-derived mesenchymal stem cells: biological characteristics and potential role in therapy of degenerative diseases Cell and Tissue Research 331 2008 157 163 (Pubitemid 350265499)
20. J.B. Kim, H.M. Wright, M. Wright, and B.M. Spiegelman ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand Proceedings of the National Academy of Sciences of the United States of America 95 1998 4333 4337 (Pubitemid 28207912)
21. C.E. Lowe, S. O'Rahilly, and J.J. Rochford Adipogenesis at a glance Journal of Cell Science 124 2011 2681 2686
22. A. Marcus, and D. Woodbury Fetal stem cells from extra-embryonic tissues: do not discard Journal of Cellular and Molecular Medicine 12 2008 730 742 (Pubitemid 351718061)
23. E.B. Maria, L. Franco, and E.F. Willem Mesenchymal stromal cells: a novel treatment modality for tissue repair Annals of the New York Academy of Sciences 1176 2009 101 117
24. H. Mizuno, M. Tobita, and A.C. Uysal Concise review: adipose-derived stem cells as a novel tool for future regenerative medicine Stem Cells 30 2012 804 810 Review
25. T. Montemurro, G. Andriolo, E. Montelatici, G. Weissmann, M. Crisan, and M.R. Colnaghi Differentiation and migration properties of human fetal umbilical cord perivascular cells: potential for lung repair Journal of Cellular and Molecular Medicine 15 2011 796 808
26. A.J. Nauta, and W.E. Fibbe Immunomodulatory properties of mesenchymal stromal cells Blood 110 2007 3499 3506 (Pubitemid 350159613)
27. R. Nogales-Cadenas, P. Carmona-Saez, M. Vazquez, C. Vicente, X. Yang, and F. Tirado GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information Nucleic Acids Research 37 2009 W317 W322
28. J.M. Ntambi, and K. Young-Cheul Adipocyte differentiation and gene expression Journal of Nutrition 130 2000 3122S 3126S Review (Pubitemid 32005353)
29. M. Ogawa Differentiation and proliferation of hematopoietic stem cells Blood 81 1993 2844 2853 (Pubitemid 23162099)
30. B.H. Park, L. Qiang, and S.R. Farmer Phosphorylation of C/EBPbeta at a consensus extracellular signal-regulated kinase/glycogen synthase kinase 3 site is required for the induction of adiponectin gene expression during the differentiation of mouse fibroblasts into adipocytes Molecular and Cell Biology 24 2004 8671 8680 (Pubitemid 39245086)
31. F. Picard, M. Kurtev, N. Chung, A. Topark-Ngarm, T. Senawong, and R. Machado De Oliveira Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma Nature 429 2004 771 776 (Pubitemid 38833129)
32. M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, and J.D. Mosca Multilineage potential of adult human mesenchymal stem cells Science 284 1999 143 147 (Pubitemid 29282067)
33. D.J. Prockop Marrow stromal cells as stem cells for nonhematopoietic tissues Science 276 1997 71 74 (Pubitemid 27161245)
34. E. Ragni, M. Viganò, P. Rebulla, G. Giordano, and L. Lazzari What is beyond a qRT-PCR study on mesenchymal stem cell differentiation properties: how to choose the most reliable housekeeping genes Journal of Cellular and Molecular Medicine 17 2013 168 180
35. J.E. Reusch, and D.J. Klemm Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis Journal of Biological Chemistry 277 2001 1426 1432
36. E.D. Rosen, C.H. Hsu, X. Wang, S. Sakai, M.W. Freeman, and F.J. Gonzalez C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway Genes and Development 16 2002 22 26 (Pubitemid 34049634)
37. H.K. Salem, and C. Thiemermann Mesenchymal stromal cells: current understanding and clinical status Stem Cells 28 2010 585 596
38. R. Sarugaser, D. Lickorish, D. Baksh, M.M. Hosseini, and J.E. Davies Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors Stem Cells 23 2005 220 229 (Pubitemid 40239517)
39. M.A. Scott, V.T. Nguyen, B. Levi, and A.W. James Current methods of adipogenic differentiation of mesenchymal stem cells Stem Cells and Development 20 2011 1793 1804 (review)
40. K. Seshareddy, D. Troyer, and M.L. Weiss Method to isolate mesenchymal-like cells from Wharton's jelly of umbilical cord Methods in Cell Biology 86 2008 101 119
41. R. Siersbæk, and S. Mandrup Transcriptional networks controlling adipocyte differentiation Cold Spring Harbor Symposia on Quantitative Biology 76 2011 247 255 (review)
42. D. Tabas-Madrid, R. Nogales-Cadenas, and A. Pascual-Montano GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics Nucleic Acids Research 40 2012 478 483
43. Q.Q. Tang, and M.D. Lane Adipogenesis: from stem cell to adipocyte Annual Review of Biochemistry 81 2012 715 736 (review)
44. J.A. Thomson, J. Itskovitz-Eldor, S.S. Shapiro, M.A. Waknitz, J.J. Swiergiel, and V.S. Marshall Embryonic stem cell lines derived from human blastocysts Science 282 1998 1145 1147 (Pubitemid 28516247)
45. P. Tontonoz, and B.M. Spiegelman Fat and beyond: the diverse biology of PPARγ Annual Review of Biochemistry 77 2008 289 312
46. Y. Zhang, D. Khan, J. Delling, and E. Tobiasch Mechanisms underlying the osteo- and adipo-differentiation of human mesenchymal stem cells The Scientific World Journal 2012 2012 793823
47. J.W. Zhang, D.J. Klemm, C. Vinson, and M.D. Lane Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis Journal of Biological Chemistry 279 2004 4471 4478 (Pubitemid 38199037)
48. S. Zia, J. Toelen, M.M. da Cunha, P. Dekoninck, P. de Coppi, and J. Deprest Routine clonal expansion of mesenchymal stem cells derived from amniotic fluid for perinatal applications Prenatal Diagnosis 23 2013 1 8
49. P.A. Zuk, M. Zhu, H. Mizuno, J. Huang, J.W. Futrell, and A.J. Katz Multilineage cells from human adipose tissue: implications for cell-based therapies Tissue Engineering 7 2001 211 228 (Pubitemid 32295155)