Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of l-prolyl-l-leucyl-glycinamide (PLG) modified in the l-proline or l-proline and l-leucine scaffolds

European Journal of Medicinal Chemistry

Volumn 69, Issue , 2013, Pages 146-158

  Ferreira Da Costa, Joana ^a   Caamaño, Olga ^a   Fernández, Franco ^a   García Mera, Xerardo ^a   Sampaio Dias, Ivo E ^a,c   Brea, José Manuel ^a,b   Cadavid, María Isabel ^a,b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Universidade de Porto ^*  (Spain)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

Dopamine receptors; Peptide mimetics; PLG

Indexed keywords

DOPAMINE RECEPTOR; LEUCINE; PROLINE; PROLYLLEUCYLGLYCINAMIDE; PROPYLNORAPOMORPHINE;

ALLOSTERISM; ARTICLE; DRUG EFFECT; DRUG SYNTHESIS; RECEPTOR BINDING;

DOPAMINE RECEPTORS; PEPTIDE MIMETICS; PLG;

ALLOSTERIC REGULATION; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LEUCINE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OLIGOPEPTIDES; PROLINE; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84883491787     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.08.001     Document Type: Article

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