Design and synthesis of photoaffinity-labeling ligands of the L-prolyl-L-leucylglycinamide binding site involved in the allosteric modulation of the dopamine receptor

Journal of Medicinal Chemistry

Volumn 49, Issue 1, 2006, Pages 307-317

  Fisher, Abigail ^a   Mann, Amandeep ^b   Verma, Vaneeta ^b   Thomas, Nancy ^b   Mishra, Ram K ^b   Johnson, Rodney L ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AZIDE; DOPAMINE 2 RECEPTOR; GAMMA LACTAM DERIVATIVE; HYDROXYL GROUP; LIGAND; PROLYLLEUCYLGLYCINAMIDE; PROPYLNORAPOMORPHINE;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; COW; CROSS LINKING; DRUG BINDING SITE; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MACROMOLECULE; NONHUMAN; PHOTOAFFINITY LABELING; REACTION ANALYSIS; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION;

ALLOSTERIC REGULATION; ANIMALS; APOMORPHINE; BINDING SITES; CATTLE; DOPAMINE AGENTS; DRUG DESIGN; LIGANDS; MOLECULAR CONFORMATION; MSH RELEASE-INHIBITING HORMONE; PHOTOAFFINITY LABELS; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 30444456827     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050644n     Document Type: Article

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