Airway deposition of nebulized gene delivery nanocomplexes monitored by radioimaging agents

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 3, 2013, Pages 471-480

  Manunta, Maria D I ^a   McAnulty, Robin J ^b   McDowell, Amy ^c   Jin, Jing ^d   Ridout, Deborah ^a   Fleming, John ^e   Bottoms, Stephen E ^b   Tossici Bolt, Livia ^e   Laurent, Geoffrey J ^b,g   Biassoni, Lorenzo ^c   O'Callaghan, Christopher ^a,f   Hart, Stephen L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^f UNIVERSITY OF LEICESTER   (United Kingdom)

^g UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Airways; Cystic fibrosis; Gene delivery; Imaging; Scintigraphy

Indexed keywords

TECHNETIUM 99M;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION; GENE TARGETING; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATORY CELL; LUNG DISEASE; LUNG LAVAGE; LUNG PARENCHYMA; LUNG SCINTISCANNING; MALE; NEBULIZATION; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; SWINE;

ANIMALS; CYSTIC FIBROSIS; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MOLECULAR IMAGING; NANOCONJUGATES; NEBULIZERS AND VAPORIZERS; PLASMIDS; RADIOPHARMACEUTICALS; RESPIRATORY MUCOSA; RESPIRATORY SYSTEM; SWINE; TECHNETIUM;

EID: 84883476151     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0030OC     Document Type: Article

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