Montelukast prevents microparticle-induced inflammatory and functional alterations in human bronchial smooth muscle cells

Pharmacological Research

Volumn 76, Issue , 2013, Pages 149-156

  Fogli, Stefano ^a   Stefanelli, Fabio ^a   Neri, Tommaso ^a   Bardelli, Claudio ^b   Amoruso, Angela ^b   Brunelleschi, Sandra ^b   Celi, Alessandro ^a   Breschi, Maria Cristina ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

2 Agonists; Airway smooth muscle cell; Bronchial inflammation; Cell signaling; Microparticles; Montelukast

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CYCLOOXYGENASE 2; INTERLEUKIN 8; MONTELUKAST; PROSTAGLANDIN E2;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRONCHUS MUSCLE; CELL FUNCTION; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; DENSITOMETRY; ENZYME RELEASE; GENE EXPRESSION; GENE SWITCHING; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MACROPHAGE; MEMBRANE MICROPARTICLE; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

AIRWAY SMOOTH MUSCLE CELL; BRONCHIAL INFLAMMATION; CELL SIGNALING; INDOMETHACIN (PUBCHEM CID 3715); MICROPARTICLES; MONTELUKAST; MONTELUKAST SODIUM (PUBCHEM CID 23663996); NS398 (PUBCHEM CID 4553); SALBUTAMOL EMISULPHATE (PUBCHEM CID 39859); Β2-AGONISTS;

ACETATES; ACTIVE TRANSPORT, CELL NUCLEUS; ANTI-ASTHMATIC AGENTS; BRONCHI; CELL LINE; CELL-DERIVED MICROPARTICLES; CELLS, CULTURED; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; MONOCYTES; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; QUINOLINES; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION;

EID: 84883467233     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2013.08.001     Document Type: Article

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