Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: Role of peroxisome proliferator-activated receptors

Journal of Immunology

Volumn 170, Issue 2, 2003, Pages 1043-1051

  Pang, Linhua ^a   Nie, Mei ^a   Corbett, Lisa ^a   Knox, Alan J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; CIGLITAZONE; CYCLOOXYGENASE 2; CYTOKINE; CYTOSKELETON PROTEIN; FLURBIPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEAR PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; PROSTAGLANDIN E2; RECOMBINANT INTERLEUKIN 1BETA;

AIRWAY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CELL LYSATE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; SMOOTH MUSCLE;

EID: 0037438456     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.2.1043     Document Type: Article

References (49)

1. DuBois, R. N., S. B. Abramson, L. Crofford, R. A. Cupta, L. S. Simon, L. B. A. van de Putte, and P. E. Lipsky. 1998. Cyclooxygenase in biology and disease. FASEB J. 12:1063.
2. Kopp, E., and S. Ghosh. 1994. Inhibition of NF-κB by sodium salicylate and aspirin. Science 265:956.
3. Mitchell, J. A., M. Saunders, P. J. Barnes, R. Newton, and M. Belvisi. 1997. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor κB) activation: role of arachidonic acid. Mol. Pharmacol. 51:907.
4. Meade, E. A., T. M. McIntyre, G. A. Zimmerman, and S. M. Prescott. 1999. Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. J. Biol. Chem. 274:8328.
5. Staels, B., W. Koening, A. Habib, R. Merval, M. Lebret, I. P. Torra. P. Delerive. A. Fadel, G. Chinetti, J, C. Fruchart, et al. 1998. Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators. Nature 393:790.
6. Paik, J. H., J. H. Ju, J. Y. Lee, M. D. Boudreau, and D. H. Hwang. 2000. Two opposing effects of nonsteroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase mediation through different signaling pathways. J. Biol. Chem. 275:28173.
7. Inoue, H., T. Tanabe, and K. Umesono. 2000. Feedback control of cyclooxygenase-2 expression through PPARγ. J. Biol. Chem. 275:28028.
8. Corton, J, C., S. P. Anderson, and A. Stauber. 2000. Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators. Annu. Rev. Pharmacol. Toxicol. 40:491.
9. Ricote, M., A. C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass. 1998. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 391:79.
10. Forman, B. M., J. Chen, and R. M. Evans. 1997. Hypolipidemic, drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and γ. Proc. Natl. Acad. Sci. USA 94:4312.
11. 4 pathway to inflammation control. Nature 384:39.
12. Jiang, C., A. T. Ting, and B. Seed. 1998. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 391:82.
13. Marx, N., G. Sukhova, C. Murphy, P. Libby, and J. Plutzky. 1998. Macrophages in human atheroma contain PPART: differentiation-dependent peroxisomal proliferator-activated receptor γ (PPARγ) expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes in vitro. Am. J. Pathol. 153:17.
14. Elias, J. A., Y. Wu, T. Zheng, and R. Panettieri. 1997, Cytokine- and virus-stimulated airway smooth muscle cells produce IL-1 I and other IL-6-type cyto kines. Am. J. Physiol. 273:L648.
15. Pang, L., and A. J. Knox. 1998. Bradykinin stimulates IL-8 production in cultured human airway smooth muscle cells: role of cyclooxygenase products. J. Immunol. 161:2509.
16. Pang, L., and A. J. Knox. 2001. Regulation of TNF-α-induced eotaxin release from cultured human airway smooth muscle cells by β2-agonists and corticosteroids. FASEB J. 15:261.
17. McKay, S., J. C. de Jongste, P. R. Saxena, and H. S. Sharma. 1998. Angiotensin II induces hypertrophy of human airway smooth muscle cells: expression of transcription factors and transforming growth factor-β1. Am. J. Respir. Cell Mol. Biol. 18:823.
18. Knox, A. J., L. Corbett, J. Stocks, E. Holland, Y. M. Zhu, and L. Pang. 2001. Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism. FASEB J. 15:2480.
19. Pang, L., and A. J. Knox. 1997. Effect of interleukin-1β, tumour necros is factor-α and interferon-γ on the induction of cyclo-oxygenase-2 in cultured human airway smooth muscle cells. Br. J. Pharmacol. 121:579.
20. 2 release by bradykinin in human airway smooth muscle cells: involvement of cyclooxygenase-2 induction. Am. J. Physiol. 273:L1132.
21. Belvisi, M. G., M. A. Saunders, E. B. Haddad, S. J. Hirst, M. H. Yacoub. P. J. Barnes, and J. A. Mitchell. 1997. Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type. Br. J. Pharmacol. 120:910.
22. Belvisi, M. G., M. Saunders, M. Yacoub, and J. A. Mitchell. 1998. Expression of cyclo-oxygenase-2 in human airway smooth muscle is associated with profound reductions in cell growth. Br. J. Pharmacol. 125:1102.
23. Pang, L., E. Holland, and A. J. Knox. 1998. Role of cyclo-oxygenase-2 induction in interleukin-1β induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline. Br. J. Pharmacol. 125:1320.
24. Pang, L., E. Holland, and A. J. Knox. 1998. Impaired cAMP production in human airway smooth muscle cells by bradykinin: role of cyclooxygenase products. Am. J. Physiol. 275:L322.
25. Pang, L., A. Pitt, D. Petkova, and A. J. Knox. 1998. The COX-1/COX-2 balance in asthma. Clin. Exp. Allergy 28:1050.
26. 2 on interleukin-1β-induced cyclooxygenase-2 expression in human airway smooth-muscle cells. Am. J. Respir. Crit. Care Med. 162:2272.
27. 2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells. J. Biol. Chem. 274:1005.
28. Pontsler, A. V., A. S. Hilaire, G. K. Marathe, G. A. Zümmerman, and T. M. McIntyre. 2002. Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor γ and oxidized alkyl phospholipids from oxidized low density lipoprotein, J. Biol. Chem. 277:13029.
29. Newton, R., L. M. Kuitert, M. Bergmann, I. M. Adcock, and P. J. Barnes, 1997. Evidence for involvement of NF-κB in the transcriptional control of COX-2 gene expression by IL-1β. Biochem. Biophys. Res. Common. 237:28.
30. Inoue, H., C. Yokoyama, S. Hara, Y. Tone, and T. Tanabe. 1995. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells: involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J. Biol. Chem. 270:24965.
31. Kim, Y., and S. M. Fischer. 1998. Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells: regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J. Biol. Chem. 273:27686.
32. Xu, X. M., L. Sansores-Garcia, X. M. Chen, N. Matijevic-Aleksic, M. Du, and K. K. Wu 1999. Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate. Proc. Natl. Acad. Sci. USA 96:5292.
33. Bonazzi, A., V. Mastyugin, P. A. Mieyal, M. W. Dunn, and M. Laniado-Scheartzman. 2000. Regulation of cyclooxygenase-2 by hypoxia and peroxisome proliferators in the corneal epithelium. J. Biol. Chem. 275:2837.
34. Pang, L., and J. R. S. Hoult. 1996. Induction of cyclooxygenase and nitric oxide synthase in endotoxin-activated J774 macrophages is differentially regulated by indomethacin: enhanced cyclooxygenase-2 protein expression but reduction of inducible nitric oxide synthase. Eur. J. Pharmacol. 317:151.
35. Kliewer, S. A., S. S. Sundseth, S. A. Jones, P. J. Brown, G. B. Wisely, C. S. Koble, P. Devchand, W. Wahli, T. M. Willson. J. M. Lenhard, and J. M. Lehmann. 1997. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ. Proc. Natl. Acad. Sci. USA 94:4318.
36. Yu, K., W. Bayona, C. B. Kallen, H. P. Harding, C. P. Ravera, G. McMahon, M. Brown, and M. A. Lazar. 1995. Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J. Biol. Chem. 270:23975.
37. Ledwith, B. J., C. J. Pauley, L. K. Wagner, C. L. Rokos, D. W. Alberts, and S. Manam. 1997. Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells. J. Biol. Chem. 272:3707.
38. 2. J. Biol. Chem. 274:17042.
39. Delerive, P., K. De Bosscher, S. Besnard, W. Vanden Berghe, J. M. Peters, F. J. Gonzalez, J.-C. Fruchart, A. Tedgui, G. Haegeman, and B. Staels. 1999. Peroxisome proliferator-activated receptor a negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1. J. Biol. Chem. 274:32648.
40. Subbaramaiah, K., D. T. Lin, J. C. Hart, and A. J. Dannenberg. 2001. Peroxisome proliferator-activated receptor γ ligands suppress the transcriptional activation of cyclooxygenase-2: evidence for involvement of activator protein-1 and CREB-binding, protein/p300. J. Biol. Chem. 276:12440.
41. Coleman, R. A., W. L. Smith, and S. Narumiya. 1994. International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev. 46:205.
42. Inoue, H., T. Nanayama, S. Hara, C. Yokoyama, and T. Tanabe. 1994. The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells. FEBS Lett. 350:51.
43. 2 regulation of cyclooxygenase expression in keratinocytes is mediated via cyclic nucleotide-linked prostaglandin receptors. J. Lipid Res. 41:873.
44. Lo, C. J., M. Fu, F. R. Lo, and H. G. Cryer. 2000. Cyclooxygenase 2 (CO-2) gene activation is regulated by cyclic adenosine monophosphate. Shock 13:41.
45. 2, upregulates cyclooxygenase-2 expression in lipopolysaccharide-stimulated RAW 264.7 macrophages. Biochem. Biophys. Res. Commun. 272:744.
46. 2 and nonsteroidal anti-inflammatory drugs. Biochem. Biophys. Res. Commun. 278:790.
47. Quellet, M., and M. D. Percival. 1995. Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms. Biochem. J. 306:247.
48. Rosenstock, M., A. Danon, M. Rubin, and G. Rimon. 2001. Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs. Eur. J. Pharmacol. 412:10l.
49. Copeland, R. A., J. M. Williams, J. Giannaras, S. Nurnberg, M. Covinton, D. Pinto, S. Pick, and J. M. Trzaskos. 1994. Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase. Proc. Natl. Acad. Sci. USA 91:11202.