Synthesis, anti-inflammatory activity, and QSAR study of some Schiff bases derived from 5-mercapto-3-(4′-pyridyl)-4H-1,2,4-triazol-4-yl- thiosemicarbazide

Medicinal Chemistry Research

Volumn 22, Issue 10, 2013, Pages 4953-4963

  Sachdeva, Harshita ^a   Dwivedi, Diksha ^a   Arya, Kapil ^b   Khaturia, Sarita ^a   Saroj, Rekha ^a  

^a MODY UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

^b UNIVERSITY OF DELHI   (India)

Author keywords

Anti inflammatory; Microwave irradiation; QSAR; Schiff bases; Triazoles

Indexed keywords

2 (2 CHLOROBENZYLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINE CARBOTHIOAMIDE; 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINECARBOTHIOAMIDE; 2 (3 CHLOROBENZYLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINE CARBOTHIOAMIDE; 2 (3 HYDROXY 4 METHOXYBENZYLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINE CARBOTHIOAMIDE; 2 (4 CHLOROBENZYLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINE CARBOTHIOAMIDE; 2 (4 FLUOROBENZYLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINE CARBOTHIOAMIDE; 2 (4 METHOXYBENZYLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINE CARBOTHIOAMIDE; 2 (4 NITROBENZYLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1, 2,4 TRIAZOL 4YL]HYDRAZINE CARBOTHIAMIDE; 2 (5 BROMO 2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINECARBOTHIOAMIDE; 2 (5 CHLORO 2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINECARBOTHIOAMIDE; 2 (5 METHYL 2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDEN) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINECARBOTHIOAMIDE; 2 BENZYLIDEN N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINE CARBOTHIAMIDE; 2-(5 NITRO 2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDEN ) N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL]HYDRAZINECARBOTHIOAMIDE; 5 MERCAPTO 3 (4' PYRIDYL) 4H 1,2,4 TRIAZOL 4 YL THIOSEMICARBAZIDE; ALDEHYDE DERIVATIVE; CARRAGEENAN; N [3 (PYRIDIN 4 YL) 5 SULFANYL 4H 1,2,4 TRIAZOL 4 YL] 2 (3,4,5 TRIMETHOXYBENZYLIDENE) HYDRAZINE CARBOTHIOAMIDE; SCHIFF BASE; THIOSEMICARBAZIDE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG SYNTHESIS; HEATING; IN VIVO STUDY; MICROWAVE IRRADIATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; REDUCTION; TOXICITY TESTING;

EID: 84883464414     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-013-0507-6     Document Type: Article

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