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Volumn 13, Issue 3, 2005, Pages 717-724
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Synthesis and structure-activity relationships of 6-enoxy}nicotinamide derivatives as a novel class of NCX inhibitors: A QSAR study
a
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Author keywords
Anti arrhythmias; NCX; Sodium calcium exchanger; Traditional QSAR
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Indexed keywords
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N (2 METHYLBENZYL)NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N (3 HYDROXYBENZYL)NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N (3 METHOXYBENZYL)NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N (3 METHYLBENZYL)NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N (3 NITROBENZYL)NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N (4 METHYLBENZYL)NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N [3 (METHYLAMINO)BENZYL]NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N [3 (TRIFLUOROMETHYL)BENZYL] NICOTINAMIDE;
6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY] N [3 [(METHYLSULFONYL)AMINO]BENZYL] NICOTINAMIDE HYDROBROMIDE;
ETHYL 3 [[[[6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY]PYRIDIN 3 YL]CARBONYL]AMINO]METHYL]BENZOATE HYDROBROMIDE;
N (3 AMINOBENZYL) 6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY]NICOTINAMIDE;
N (3 BROMOBENZYL) 6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY]NICOTINAMIDE;
N (3 CHLOROBENZYL) 6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY]NICOTINAMIDE;
N (3 CYANOBENZYL) 6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY]NICOTINAMIDE;
N (3 FLUOROBENZYL) 6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY]NICOTINAMIDE;
N [3 (DIMETHYLAMINO)BENZYL] 6 [4 [(3 FLUOROBENZYL)OXY]PHENOXY]NICOTINAMIDE HYDROBROMIDE;
NICOTINAMIDE DERIVATIVE;
PROTEIN INHIBITOR;
SODIUM CALCIUM EXCHANGE PROTEIN;
SODIUM CALCIUM EXCHANGER INHIBITOR;
UNCLASSIFIED DRUG;
ARTICLE;
DRUG INDICATION;
DRUG MECHANISM;
DRUG POTENCY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG TARGETING;
HEART ARRHYTHMIA;
HEART MUSCLE NECROSIS;
HYDROPHOBICITY;
IC 50;
INHIBITION KINETICS;
MYOCARDIAL DISEASE;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
MAGNETIC RESONANCE SPECTROSCOPY;
NIACINAMIDE;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
SODIUM-CALCIUM EXCHANGER;
SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;
OXY;
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EID: 11844256305
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2004.10.047 Document Type: Article |
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Times cited : (14)
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References (25)
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