Ectopic PDX-1 expression directly reprograms human keratinocytes along pancreatic insulin-producing cells fate

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Mauda Havakuk, Michal ^a,b   Litichever, Naomi ^a,b   Chernichovski, Ellad ^a,b   Nakar, Odelia ^a,b   Winkler, Eyal ^a   Mazkereth, Ram ^a   Orenstein, Arie ^a   Bar Meir, Eran ^a   Ravassard, Philippe ^c   Meivar Levy, Irit ^a   Ferber, Sarah ^a,b  

^a SHEBA MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PAX4; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR SOX17; BIOLOGICAL MARKER; HOMEODOMAIN PROTEIN; PANCREAS HORMONE; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL LINEAGE; CONTROLLED STUDY; ECTODERM; ENDODERM; GENE EXPRESSION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INSULIN RELEASE; KERATINOCYTE; NEWBORN; NUCLEAR REPROGRAMMING; PANCREAS CELL; PANCREAS ISLET BETA CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSCRIPTION INITIATION; ADULT; ANIMAL; CELL STRAIN 3T3; CULTURE TECHNIQUE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOUSE; RAT;

3T3 CELLS; ADULT; ANIMALS; BIOLOGICAL MARKERS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; ECTODERM; ENDODERM; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; INFANT, NEWBORN; INSULIN-SECRETING CELLS; KERATINOCYTES; MICE; PANCREATIC HORMONES; RATS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 80054756679     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026298     Document Type: Article

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