Network and Atomistic Simulations Unveil the Structural Determinants of Mutations Linked to Retinal Diseases

PLoS Computational Biology

Volumn 9, Issue 8, 2013, Pages

  Mariani, Simona ^a,b   Dell'Orco, Daniele ^c   Felline, Angelo ^a,b   Raimondi, Francesco ^a,b   Fanelli, Francesca ^a,b  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b DULBECCO TELETHON INSTITUTE   (Italy)

^c UNIVERSITY OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROPHYSIOLOGY; OPHTHALMOLOGY; SIGNALING;

% REDUCTIONS; ATOMISTIC SIMULATIONS; MUTATIONAL EFFECTS; NETWORK SIMULATION; PHOTOTRANSDUCTION; RETINAL DISEASE; SIGNALING NETWORKS; STRUCTURAL DETERMINANTS; TRANSDUCIN; VISION IMPAIRMENTS;

MOLECULAR DYNAMICS;

PHOSPHODIESTERASE VI; TRANSDUCIN;

ARTICLE; BINDING SITE; CATALYSIS; ENZYME ACTIVATION; GENE MUTATION; MATHEMATICAL MODEL; MISSENSE MUTATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTANT; NOUGARET CONGENITAL NIGHT BLINDNESS; PHENOTYPE; PHOTOTRANSDUCTION; RETINA DISEASE; SIGNAL TRANSDUCTION;

EID: 84883415611     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003207     Document Type: Article

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