Structural and biochemical characterization of the GTPγS-, GDP · P(i)- , and GDP-bound forms of a GTPase-deficient GLY42 → Val mutant of G(iα1)

Biochemistry

Volumn 36, Issue 50, 1997, Pages 15660-15669

  Raw, Andre S ^a   Coleman, David E ^a   Gilman, Alfred G ^a   Sprang, Stephen R ^b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; HYDROGEN BONDING; HYDROLYSIS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RATS; TRYPSIN;

ESCHERICHIA COLI;

EID: 0031471341     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971912p     Document Type: Article

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