Digoxin inhibits retinal ischemia-induced HIF-1α expression and ocular neovascularization

FASEB Journal

Volumn 24, Issue 6, 2010, Pages 1759-1767

  Yoshida, Tsunehiko ^a   Zhang, Huafeng ^a   Iwase, Takeshi ^a   Shen, Jikui ^a   Semenza, Gregg L ^a   Campochiaro, Peter A ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Age related macular degeneration; Angiogenesis; Cardiac glycosides; Diabetic retinopathy

Indexed keywords

ANGIOPOIETIN RECEPTOR; BETA ACTIN; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; DIGOXIN; ERYTHROPOIETIN; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN BNIP3; STEM CELL FACTOR RECEPTOR; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BRUCH MEMBRANE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA ISCHEMIA; RETINA NEOVASCULARIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; SUBRETINAL NEOVASCULARIZATION;

ANIMALS; BLOTTING, WESTERN; CARDIOTONIC AGENTS; CHOROIDAL NEOVASCULARIZATION; DIGOXIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; OXYGEN; REPERFUSION INJURY; RETINAL NEOVASCULARIZATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTORS;

MURINAE; MUS;

EID: 77953515701     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-145664     Document Type: Article

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