Mycological analysis and multimycotoxins in maize from rural subsistence farmers in the former Transkei, South Africa

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 34, 2013, Pages 8232-8240

  Shephard, Gordon S ^a   Burger, Hester Mari ^a   Gambacorta, Lucia ^b   Krska, Rudolf ^c   Powers, Stephen P ^d   Rheeder, John P ^a   Solfrizzo, Michele ^b   Sulyok, Michael ^c   Visconti, Angelo ^b   Warth, Benedikt ^c   Van Der Westhuizen, Liana ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b INSTITUTE OF SCIENCES OF FOOD PRODUCTION   (Italy)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^d VICAM   (United States)

Author keywords

deoxynivalenol; fumonisin; maize; multimycotoxin; mycotoxin; ochratoxin; secondary metabolites; zearalenone

Indexed keywords

DEOXYNIVALENOL; FUMONISIN; MAIZE; MULTIMYCOTOXIN; MYCOTOXIN; OCHRATOXIN; SECONDARY METABOLITES; ZEARALENONE;

AFLATOXINS; AGRICULTURE; ANTIGEN-ANTIBODY REACTIONS; METABOLITES;

TOXICITY;

MYCOTOXIN;

ARTICLE; CHEMISTRY; FOOD CONTAMINATION; FUNGUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MAIZE; METABOLISM; MICROBIOLOGY; SOUTH AFRICA; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD CONTAMINATION; FUNGI; MYCOTOXINS; SOUTH AFRICA; TANDEM MASS SPECTROMETRY; ZEA MAYS;

EID: 84883314214     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf4021762     Document Type: Article

References (30)

1. Somdyala, N. I. M.; Bradshaw, D.; Gelderblom, W. C. A.; Parkin, D. M. Cancer incidence in a rural population of South Africa, 1998-2002 Int. J. Cancer 2010, 127, 2420-2429
2. Rheeder, J. P.; Marasas, W. F. O.; Thiel, P. G.; Sydenham, E. W.; Shephard, G. S.; Van Schalkwyk, D. J. Fusarium moniliforme and fumonisins in corn in relation to human esophageal cancer in Transkei Phytopathology 1992, 82, 353-357
3. Shephard, G. S.; Marasas, W. F. O.; Burger, H. M.; Somdyala, N. I. M.; Rheeder, J. P.; Van der Westhuizen, L.; Gatyeni, P.; Van Schalkwyk, D. J. Exposure assessment for fumonisins in the former Transkei region of South Africa Food Addit. Contam. 2007, 24, 621-629
4. Van der Westhuizen, L.; Shephard, G. S.; Rheeder, J. P.; Somdyala, N. I. M.; Marasas, W. F. O. Sphingoid base levels in humans consuming fumonisin-contaminated maize in rural areas of the former Transkei, South Africa: a cross-sectional study Food Addit. Contam. Part A 2008, 25, 1385-1391
5. Van der Westhuizen, L.; Shephard, G. S.; Rheeder, J. P.; Burger, H. M. Individual fumonisin exposure and sphingoid base levels in rural populations consuming maize in South Africa Food Chem. Toxicol. 2010, 48, 1698-1703
6. Burger, H. M.; Lombard, M. J.; Shephard, G. S.; Rheeder, J. P.; Van der Westhuizen, L.; Gelderblom, W. C. A. Dietary fumonisin exposure in a rural population of South Africa Food Chem. Toxicol. 2010, 48, 2103-2108
7. Bolger, M.; Coker, R. D.; DiNovi, M.; Gaylor, D.; Gelderblom, W.; Olsen, M.; Paster, N.; Riley, R. T.; Shephard, G.; Speijers, G. J. A. Fumonisins In Safety Evaluation of Certain Mycotoxins in Food; WHO Food Additives Series 47; FAO Food and Nutrition Paper 74; Prepared by the 56th Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA); WHO: Geneva, Switzerland, 2001; pp 103-279.
8. Marasas, W. F. O.; Van Rensburg, S. J.; Mirocha, C. J. Incidence of Fusarium species and the mycotoxins, deoxynivalenol and zearalenone, in corn produced in esophageal cancer areas in Transkei J. Agric. Food Chem. 1979, 27, 1108-1112
9. Thiel, P. G.; Meyer, C. J.; Marasas, W. F. O. Natural occurrence of moniliformin together with deoxynivalenol and zearalenone in Transkeian corn J. Agric. Food Chem. 1982, 30, 308-312
10. Gelderblom, W. C. A.; Thiel, P. G.; Marasas, W. F. O.; Van Der Merwe, K. J. Natural occurrence of fusarin C, a mutagen produced by Fusarium moniliforme, in corn J. Agric. Food Chem. 1984, 32, 1064-1067
11. Sydenham, E. W.; Thiel, P. G.; Marasas, W. F. O.; Shephard, G. S.; Van Schalkwyk, D. J.; Koch, K. R. Natural occurrence of some Fusarium mycotoxins in corn from low and high esophageal cancer prevalence areas of the Transkei, southern Africa J. Agric. Food Chem. 1990, 38, 1900-1903
12. Sewram, V.; Nieuwoudt, T. W.; Marasas, W. F. O.; Shephard, G. S.; Ritieni, A. Determination of the Fusarium mycotoxins, fusaproliferin and beauvericin by high-performance liquid chromatography-electrospray ionization mass spectrometry J. Chromatogr., A 1999, 858, 175-185
13. Shephard, G. S.; Sewram, V.; Nieuwoudt, T. W.; Marasas, W. F. O.; Ritieni, A. Production of the mycotoxins fusaproliferin and beauvericin by South African isolates in the Fusarium section Liseola J. Agric. Food Chem. 1999, 47, 5111-5115
14. Sewram, V.; Nieuwoudt, T. W.; Marasas, W. F. O.; Shephard, G. S.; Ritieni, A. Determination of the mycotoxin moniliformin in cultures of Fusarium subglutinans and in naturally contaminated maize by high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry J. Chromatogr., A 1999, 848, 185-191
15. Lattanzio, V. M. T.; Solfrizzo, M.; Powers, S.; Visconti, A. Simultaneous determination of aflatoxins, ochratoxin A and Fusarium toxins in maize by liquid chromatography/tandem mass spectrometry after multitoxin immunoaffinity cleanup Rapid Commun. Mass Spectrom. 2007, 21, 3253-3261
16. Sulyok, M.; Berthiller, F.; Krska, R.; Schuhmacher, R. Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize Rapid Commun. Mass Spectrom. 2006, 20, 2649-2659
17. Sulyok, M.; Krska, R.; Schuhmacher, R. A liquid chromatography/tandem mass spectrometric multi-mycotoxin method for the quantification of 87 analytes and its application to semi-quantitative screening of moldy food samples Anal. Bioanal. Chem. 2007, 389, 1505-1523
18. Mogensen, J. M.; Sørensen, S. M.; Sulyok, M.; Van der Westhuizen, L.; Shephard, G. S.; Frisvad, J. C.; Thrane, U.; Krska, R.; Nielsen, K. F. Single-kernel analysis of fumonisins and other fungal metabolites in maize from South African subsistence farmers Food Addit. Contam. Part A 2011, 28, 1724-1734
19. Warth, B.; Parich, A.; Atehnkeng, J.; Bandyopadhyay, R.; Schuhmacher, R.; Sulyok, M.; Krska, R. Quantitation of mycotoxins in food and feed from Burkina Faso and Mozambique using a modern LC-MS/MS multitoxin method J. Agric. Food Chem. 2012, 60, 9352-9363
20. Abia, W. A.; Warth, B.; Sulyok, M.; Krska, R.; Tchana, A. N.; Njobeh, P. B.; Dutton, M. F.; Moundipa, P. F. Determination of multi-mycotoxin occurrence in cereals, nuts and their products in Cameroon by liquid chromatography tandem mass spectrometry (LC-MS/MS) Food Control 2013, 31, 438-453
21. Ezekiel, C. N.; Sulyok, M.; Warth, B.; Krska, R. Multi-microbial metabolites in fonio millet (acha) and sesame seeds in Plateau State, Nigeria Eur. Food Res. Technol. 2012, 235, 285-293
22. Ezekiel, C. N.; Sulyok, M.; Warth, B.; Odebode, A. C.; Krska, R. Natural occurrence of mycotoxins in peanut cake from Nigeria Food Control 2012, 27, 338-342
23. Nelson, P. E.; Toussoun, T. A.; Marasas, W. F. O. Fusarium Species: An Illustrated Manual for Identification; Pennsylvania State University Press: University Park, PA, USA, 1983.
24. Sulyok, M.; Krska, R.; Schuhmacher, R. Application of a liquid chromatography-tandem mass spectrometric method to multi-mycotoxin determination in raw cereals and evaluation of matrix effects Food Addit. Contam. 2007, 24, 1184-1195
25. Solfrizzo, M.; De Girolamo, A.; Lattanzio, V. M. T.; Visconti, A.; Stroka, J.; Alldrick, A.; van Egmond, H. P. Results of a proficiency test for multi-mycotoxin determination in maize by using methods based on LC-MS/(MS) Qual. Assur. Saf. Crops Foods 2013, 5, 15-48
26. Bulder, A. S.; DiNovi, M.; Kpodo, K. A.; LeBlanc, J.-C.; Resnik, S.; Shephard, G. S.; Slob, W.; Walker, R.; Wolterink, G. Deoxynivalenol (addendum). In Safety Evaluation of Certain Contaminants in Food; FAO JECFA Monographs 8, WHO Food Additives Series 63, Prepared by the 72nd Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA); WHO: Geneva, Switzerland, 2011; pp 317-485.
27. JECFA, 53rd Meeting of the Joint FAO/WHO Expert Committeeon Food Additives, 2000; http://www.inchem.org/documents/jecfa/jecmono/v44jec14.htm (accessed May 15, 2013).
28. 1 correlates with its inability to alter the metabolism of sphingolipids Biochem. Pharmacol. 2012, 83, 1465-1473
29. Porter, J. K.; Bacon, C. W.; Wray, E. M.; Hagler, W. M., Jr. Fusaric acid in Fusarium moniliforme cultures, corn, and feeds toxic to livestock and the neurochemical effects in the brain and pineal gland of rats Nat. Toxins 1995, 3, 91-100
30. Grenier, B.; Oswald, I. P. Mycotoxin co-contamination of food and feed: meta-analysis of publications describing toxicological interactions World Mycotoxin J. 2011, 4, 285-313