9-norbornyl-6-chloropurine is a novel antileukemic compound interacting with cellular GSH

Anticancer Research

Volumn 33, Issue 8, 2013, Pages 3163-3168

  Plačkova, Pavla ^a   Rozumova, Nela ^a   Hřebabecky, Hubert ^a   Šala, Michal ^a   Nencka, Radim ^a   Elbert, Tomaš ^a   Dvořakova, Alexandra ^a   Votruba, Ivan ^a   Mertlikova Kaiserova, Helena ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Carbocyclic nucleoside analogs; Glutathione depletion; Glutathione S transferase; Substituted 6 chloropurines

Indexed keywords

9 NORBORNYL 6 CHLOROPURINE; ANTILEUKEMIC AGENT; CELL EXTRACT; CYSTEINE; CYSTEINYLGLYCINE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL FRACTIONATION; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; DRUG PENETRATION; ENZYME INHIBITION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; METABOLITE; PRIORITY JOURNAL;

CARBOCYCLIC NUCLEOSIDE ANALOGS; GLUTATHIONE DEPLETION; GLUTATHIONE-S-TRANSFERASE; SUBSTITUTED 6-CHLOROPURINES;

ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DRUG SCREENING ASSAYS, ANTITUMOR; EPITHELIAL CELLS; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; LEUKEMIA; PURINES; XANTHINE OXIDASE;

EID: 84883279774     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

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