-
1
-
-
33644508373
-
Dihydrofolate reductase inhibitors as antibacterial agents
-
Hawser S, Lociuro S, Islam K. Dihydrofolate reductase inhibitors as antibacterial agents. Biochem Pharmacol 2006; 71:941-948.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 941-948
-
-
Hawser, S.1
Lociuro, S.2
Islam, K.3
-
2
-
-
79959893500
-
Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors
-
Lee J, Kim KH, Jeong S. Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors. Bioorg Med Chem Lett 2011;21:4203-4205.
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 4203-4205
-
-
Lee, J.1
Kim, K.H.2
Jeong, S.3
-
3
-
-
77249137785
-
Discovery of (thienopyrimidin-2-yl) aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer
-
Sutherlin DP, Sampath D, Berry M, Castanedo G, Chang Z, Chuckowree I, et al. Discovery of (thienopyrimidin-2-yl) aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer. J Med Chem 2010;53: 1086-1097.
-
(2010)
J Med Chem
, vol.53
, pp. 1086-1097
-
-
Sutherlin, D.P.1
Sampath, D.2
Berry, M.3
Castanedo, G.4
Chang, Z.5
Chuckowree, I.6
-
4
-
-
33845627635
-
4-Aminopyrimidines as novel HIV-1 inhibitors
-
DOI 10.1016/j.bmcl.2006.09.047, PII S0960894X0601105X
-
Gadhachanda VR, Wu B, Wang Z, Kuhen KL, Caldwell J, Zondler H, et al. 4-Aminopyrimidines as novel HIV-1 inhibitors. Bioorg Med Chem Lett 2007;17:260-265. (Pubitemid 44959951)
-
(2007)
Bioorganic and Medicinal Chemistry Letters
, vol.17
, Issue.1
, pp. 260-265
-
-
Gadhachanda, V.R.1
Wu, B.2
Wang, Z.3
Kuhen, K.L.4
Caldwell, J.5
Zondler, H.6
Walter, H.7
Havenhand, M.8
He, Y.9
-
5
-
-
0242299576
-
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy) ethoxy]pyrimidines- Acyclic Nucleoside Phosphonate Analogues with Antiviral Activity
-
Hocková D, Holý A, Masojí dková M, Andrei G, Snoeck R, De Clercq E, Balzarini J. 5-Substituted-2,4-diamino-6-[2- (phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity. J Med Chem 2003;46:5064-5073. (Pubitemid 37352043)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.23
, pp. 5064-5073
-
-
Hockova, D.1
Holy, A.2
Masojidkova, M.3
Andrei, G.4
Snoeck, R.5
De Clercq, E.6
Balzarini, J.7
-
6
-
-
0347627540
-
Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore
-
DOI 10.1016/S0014-5793(03)01358-9
-
Rezk BM, Haenen GR, van der Vijgh WJ, Bast A. Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identifi cation of the antioxidant pharmacophore. FEBS Lett 2003;555:601-605. (Pubitemid 37532618)
-
(2003)
FEBS Letters
, vol.555
, Issue.3
, pp. 601-605
-
-
Rezk, B.M.1
Haenen, G.R.M.M.2
Van Der Vijgh, W.J.F.3
Bast, A.4
-
7
-
-
75749158529
-
Nucleosides part LXVI I: Synthesis of 4-amino-7(8H)pteridinone-N8- nucleosides-structural analogs of adenosine
-
Jungmann O, Pfl eiderer W. Nucleosides part LXVI I: synthesis of 4-amino-7(8H)pteridinone-N8-nucleosides-structural analogs of adenosine. Nucleos Nucleot Nucleic Acids 2009; 28(5):550-585.
-
(2009)
Nucleos Nucleot Nucleic Acids
, vol.28
, Issue.5
, pp. 550-585
-
-
Jungmann, O.1
Pfleiderer, W.2
-
8
-
-
0028965139
-
Regioselective addition of Grignard reagents to a 2-oxopurinium salt
-
Andresen G, Gundersen LL, Lundmark M, Rise F, Sundell S. Regioselective addition of Grignard reagents to a 2-oxopurinium salt. Tetrahedron 1995;51(12):3655-3664.
-
(1995)
Tetrahedron
, vol.51
, Issue.12
, pp. 3655-3664
-
-
Andresen, G.1
Gundersen, L.L.2
Lundmark, M.3
Rise, F.4
Sundell, S.5
-
9
-
-
0008230698
-
Tautomeric nature of quinonoid 6,7-dimethyl-7,8-dihydro-6H-pterin in aqueous solution: A nitrogen-15 NMR study
-
Benkovic SJ, Sammons D, Armarego WLF, Waring P, Inners R. Tautomeric nature of quinonoid 6,7-dimethyl-7,8-dihydro-6H-pterin in aqueous solution: a nitrogen-15 NMR study. J Am Chem Soc 1985;107(12):3706-3712.
-
(1985)
J Am Chem Soc
, vol.107
, Issue.12
, pp. 3706-3712
-
-
Benkovic, S.J.1
Sammons, D.2
Armarego, W.L.F.3
Waring, P.4
Inners, R.5
-
10
-
-
0032982508
-
Antioxidant activity applying an improved ABTS radical cation decolorization assay
-
DOI 10.1016/S0891-5849(98)00315-3, PII S0891584998003153
-
Re R, Pellegrini N, Pannala A, Yang M, Rice-Evans C. Antioxidant activity of applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 1999;26(9-10): 1231-1237. (Pubitemid 29262709)
-
(1999)
Free Radical Biology and Medicine
, vol.26
, Issue.9-10
, pp. 1231-1237
-
-
Re, R.1
Pellegrini, N.2
Proteggente, A.3
Pannala, A.4
Yang, M.5
Rice-Evans, C.6
-
11
-
-
0002762416
-
Techniques for studying drug metabolism in vitro
-
La Du BN, Mandel HG, Way EL (eds) Baltimore: The, Williams & Wilkins Company
-
Gillette JR. Techniques for studying drug metabolism in vitro. In: La Du BN, Mandel HG, Way EL (eds). Fundamentals of Drug Metabolism and Drug Disposition. Baltimore: The Williams & Wilkins Company; 1971. pp. 400-418.
-
(1971)
Fundamentals of Drug Metabolism and Drug Disposition
, pp. 400-418
-
-
Gillette, J.R.1
-
12
-
-
0025211779
-
Quantitation of protein
-
DOI 10.1016/0076-6879(90)82008-P
-
Stoscheck CM. Quantitation of protein. Meth Enzymol 1990;182:50-68. (Pubitemid 20154379)
-
(1990)
Methods in Enzymology
, vol.182
, pp. 50-68
-
-
Stoscheck, C.M.1
-
13
-
-
0035399633
-
New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity
-
DOI 10.1016/S0891-5849(01)00546-9, PII S0891584901005469
-
van Acker FA, Hulshof JW, Haenen GR, Menge WM, van der Vijgh WJ, Bast A. New synthetic fl avonoids as potent protectors against doxorubicin-induced cardiotoxicity. Free Radic Biol Med 2001;31(1):31-37. (Pubitemid 32568421)
-
(2001)
Free Radical Biology and Medicine
, vol.31
, Issue.1
, pp. 31-37
-
-
Van Acker, F.A.A.1
Hulshof, J.W.2
Haenen, G.R.M.M.3
Menge, W.M.P.B.4
Van Der Vijgh, W.J.F.5
Bast, A.6
-
14
-
-
0025776627
-
Preparative steps necessary for the accurate measurement of malondialdehyde by high-performance liquid chromatography
-
Lepage G, Munoz G, Champagne J, Roy CC. Preparative steps necessary for the accurate measurement of malondialdehyde by high-performance liquid chromatography. Anal Biochem 1991;197(2):277-283.
-
(1991)
Anal Biochem
, vol.197
, Issue.2
, pp. 277-283
-
-
Lepage, G.1
Munoz, G.2
Champagne, J.3
Roy, C.C.4
-
15
-
-
0028073912
-
New in vitro fluorimetric microtitration assays for toxicological screening of drugs
-
DOI 10.1007/BF00755779
-
Rat P, Korwin-Zmijowska C, Warnet JM, Adolphe M. New in vitro fl uorimetric microtitration assays for toxicological screening of drugs. Cell Biol Toxicol 1994;10(5-6):329-337. (Pubitemid 24377307)
-
(1994)
Cell Biology and Toxicology
, vol.10
, Issue.5-6
, pp. 329-337
-
-
Rat, P.1
Korwin-Zmijowska, C.2
Warnet, J.-M.3
Adolphe, M.4
-
16
-
-
0032820452
-
Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
-
DOI 10.1016/S0891-5849(99)00107-0, PII S0891584999001070
-
Wang H, Joseph JA. Quantifying cellular oxidative stress by dichlorofl uorescein assay using microplate reader. Free Radic Biol Med 1999;27(5-6):612-616. (Pubitemid 29408648)
-
(1999)
Free Radical Biology and Medicine
, vol.27
, Issue.5-6
, pp. 612-616
-
-
Wang, H.1
Joseph, J.A.2
-
17
-
-
0032839105
-
Tacrine-induced reactive oxygen species in a human liver cell line: The role of anethole dithiolethione as a scavenger
-
DOI 10.1016/S0887-2333(99)00050-8, PII S0887233399000508
-
Osseni RA, Debbasch C, Christen MO, Rat P, Warnet JM. Tacrine-induced Reactive Oxygen Species in a Human Liver Cell Line. The Role of Anethole Dithiolethione as a Scavenger. Toxicol In Vitro 1999;13(4-5):683-688. (Pubitemid 29354196)
-
(1999)
Toxicology in Vitro
, vol.13
, Issue.4-5
, pp. 683-688
-
-
Osseni, R.A.1
Debbasch, C.2
Christen, M.-O.3
Rat, P.4
Warnet, J.-M.5
-
18
-
-
0025799991
-
An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT
-
Roehm NW, Rodgers GH, Hatfi eld SM, Grasebrook AL. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J Immunol Meth 1991; 142(2):257-265.
-
(1991)
J Immunol Meth
, vol.142
, Issue.2
, pp. 257-265
-
-
Roehm, N.W.1
Rodgers, G.H.2
Hatfield, S.M.3
Grasebrook, A.L.4
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