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Volumn 9, Issue 7, 2013, Pages 641-648

Current understanding of the pathogenesis of granulomatosis with polyangiitis (Wegener's)

Author keywords

ANCA; granulomatosis with polyangiitis (Wegener's); pathogenesis; vasculitis

Indexed keywords

COMPLEMENT COMPONENT C1S INHIBITOR; CORTICOSTEROID; HLA DP ANTIGEN; HLA DPB1 ANTIGEN; HLA DPB4 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 32; INTERLEUKIN 6; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MYELOBLASTIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; PROTEINASE ACTIVATED RECEPTOR 2; SERINE PROTEINASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84883206431     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/1744666X.2013.811052     Document Type: Review
Times cited : (28)

References (58)
  • 1
    • 77958105665 scopus 로고    scopus 로고
    • Prospective long-term follow-up of patients with localised Wegener's granulomatosis: Does it occur as persistent disease stage
    • Holle JU, Gross WL, Holl-Ulrich K et al. Prospective long-term follow-up of patients with localised Wegener's granulomatosis: does it occur as persistent disease stage Ann. Rheum. Dis. 69(11), 1934-1939 (2010).
    • (2010) Ann. Rheum. Dis. , vol.69 , Issue.11 , pp. 1934-1939
    • Holle, J.U.1    Gross, W.L.2    Holl-Ulrich, K.3
  • 2
    • 73649095925 scopus 로고    scopus 로고
    • Recent progress in the genetics of Wegener's granulomatosis and Churg-Strauss syndrome
    • Wieczorek S, Holle JU, Epplen JT. Recent progress in the genetics of Wegener's granulomatosis and Churg-Strauss syndrome. Curr. Opin. Rheumatol. 22(1), 8-14 (2010).
    • (2010) Curr. Opin. Rheumatol. , vol.22 , Issue.1 , pp. 8-14
    • Wieczorek, S.1    Holle, J.U.2    Epplen, J.T.3
  • 3
    • 38149128179 scopus 로고    scopus 로고
    • Risks and relative risks of Wegener's granulomatosis among close relatives of patients with the disease
    • Knight A, Sandin S, Askling J. Risks and relative risks of Wegener's granulomatosis among close relatives of patients with the disease. Arthritis Rheum. 58(1), 302-307 (2008).
    • (2008) Arthritis Rheum. , vol.58 , Issue.1 , pp. 302-307
    • Knight, A.1    Sandin, S.2    Askling, J.3
  • 4
    • 79952328826 scopus 로고    scopus 로고
    • Are there specific genetic risk factors for the different forms of ANCA-Associated vasculitis
    • Arning L, Holle JU, Harper L et al. Are there specific genetic risk factors for the different forms of ANCA-Associated vasculitis Ann. Rheum. Dis. 70(4), 707-708 (2011).
    • (2011) Ann. Rheum. Dis. , vol.70 , Issue.4 , pp. 707-708
    • Arning, L.1    Holle, J.U.2    Harper, L.3
  • 5
    • 84864014453 scopus 로고    scopus 로고
    • Genetically distinct subsets within ANCA-Associated vasculitis
    • Lyons PA, Rayner TF, Trivedi S et al. Genetically distinct subsets within ANCA-Associated vasculitis. N. Engl. J. Med. 367(3), 214-223 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , Issue.3 , pp. 214-223
    • Lyons, P.A.1    Rayner, T.F.2    Trivedi, S.3
  • 6
    • 77952240517 scopus 로고    scopus 로고
    • A CD8+ T cell transcription signature predicts prognosis in autoimmune disease
    • McKinney EF, Lyons PA, Carr EJ et al. A CD8+ T cell transcription signature predicts prognosis in autoimmune disease. Nat. Med. 16(5), 586-591 (2010).
    • (2010) Nat. Med. , vol.16 , Issue.5 , pp. 586-591
    • McKinney, E.F.1    Lyons, P.A.2    Carr, E.J.3
  • 8
    • 34548830190 scopus 로고    scopus 로고
    • Association of silica exposure with anti-neutrophil cytoplasmic autoantibody small-vessel vasculitis: A population-based, case-control study
    • Hogan SL, Cooper GS, Savitz DA et al. Association of silica exposure with anti-neutrophil cytoplasmic autoantibody small-vessel vasculitis: a population-based, case-control study. Clin. J. Am. Soc. Nephrol. 2(2), 290-299 (2007).
    • (2007) Clin. J. Am. Soc. Nephrol. , vol.2 , Issue.2 , pp. 290-299
    • Hogan, S.L.1    Cooper, G.S.2    Savitz, D.A.3
  • 9
    • 73649138601 scopus 로고    scopus 로고
    • Clinical and immunological features of drug-induced and infection-induced proteinase 3-Antineutrophil cytoplasmic antibodies and myeloperoxidase- Antineutrophil cytoplasmic antibodies and vasculitis
    • Csernok E, Lamprecht P, Gross WL. Clinical and immunological features of drug-induced and infection-induced proteinase 3-Antineutrophil cytoplasmic antibodies and myeloperoxidase-Antineutrophil cytoplasmic antibodies and vasculitis. Curr. Opin. Rheumatol. 22(1), 43-48 (2010).
    • (2010) Curr. Opin. Rheumatol. , vol.22 , Issue.1 , pp. 43-48
    • Csernok, E.1    Lamprecht, P.2    Gross, W.L.3
  • 10
    • 0002737870 scopus 로고
    • Association of chronic nasal carriage of Staphylococcus aureus and higher relapse rates in Wegener granulomatosis
    • Stegeman CA, Tervaert JW, Sluiter WJ, Manson WL, de Jong PE, Kallenberg CG. Association of chronic nasal carriage of Staphylococcus aureus and higher relapse rates in Wegener granulomatosis. Ann. Intern. Med. 120(1), 12-17 (1994).
    • (1994) Ann. Intern. Med. , vol.120 , Issue.1 , pp. 12-17
    • Stegeman, C.A.1    Tervaert, J.W.2    Sluiter, W.J.3    Manson, W.L.4    De Jong, P.E.5    Kallenberg, C.G.6
  • 11
    • 77954619161 scopus 로고    scopus 로고
    • Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic rhinosinusitis with nasal polyps
    • Laudien M, Gadola SD, Podschun R et al. Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic rhinosinusitis with nasal polyps. Clin. Exp. Rheumatol. 28(1 Suppl. 57), 51-55 (2010).
    • (2010) Clin. Exp. Rheumatol. , vol.28 , Issue.1 SUPPL. 57 , pp. 51-55
    • Laudien, M.1    Gadola, S.D.2    Podschun, R.3
  • 12
    • 3543052882 scopus 로고    scopus 로고
    • Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-Associated glomerulonephritis
    • Yang JJ, Pendergraft WF, Alcorta DA et al. Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody- Associated glomerulonephritis. J. Am. Soc. Nephrol. 15(8), 2103-2114 (2004).
    • (2004) J. Am. Soc. Nephrol. , vol.15 , Issue.8 , pp. 2103-2114
    • Yang, J.J.1    Pendergraft, W.F.2    Alcorta, D.A.3
  • 14
    • 77956370874 scopus 로고    scopus 로고
    • Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis
    • Ciavatta DJ, Yang J, Preston GA et al. Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis. J. Clin. Invest. 120(9), 3209-3219 (2010).
    • (2010) J. Clin. Invest. , vol.120 , Issue.9 , pp. 3209-3219
    • Ciavatta, D.J.1    Yang, J.2    Preston, G.A.3
  • 15
    • 77949271551 scopus 로고    scopus 로고
    • Histopathology of systemic vasculitis
    • Holl-Ulrich K. Histopathology of systemic vasculitis. Pathologe 31(1), 67-76 (2010).
    • (2010) Pathologe , vol.31 , Issue.1 , pp. 67-76
    • Holl-Ulrich, K.1
  • 16
    • 33747428725 scopus 로고    scopus 로고
    • Effector memory T cells as driving force of granuloma formation and autoimmunity in Wegener's granulomatosis
    • Lamprecht P, Csernok E, Gross WL. Effector memory T cells as driving force of granuloma formation and autoimmunity in Wegener's granulomatosis. J. Intern. Med. 260(3), 187-191 (2006).
    • (2006) J. Intern. Med. , vol.260 , Issue.3 , pp. 187-191
    • Lamprecht, P.1    Csernok, E.2    Gross, W.L.3
  • 17
    • 84856619262 scopus 로고    scopus 로고
    • Vasculitis in 2011: The renaissance of granulomatous inflammation in AAV
    • Gadola SD, Gross WL. Vasculitis in 2011: the renaissance of granulomatous inflammation in AAV. Nat. Rev. Rheumatol. 8(2), 74-76 (2012).
    • (2012) Nat. Rev. Rheumatol. , vol.8 , Issue.2 , pp. 74-76
    • Gadola, S.D.1    Gross, W.L.2
  • 18
    • 84860250334 scopus 로고    scopus 로고
    • Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice
    • Kesel N, Köhler D, Herich L et al. Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice. Am. J. Pathol. 180(5), 2144-2155 (2012).
    • (2012) Am. J. Pathol. , vol.180 , Issue.5 , pp. 2144-2155
    • Kesel, N.1    Köhler, D.2    Herich, L.3
  • 19
    • 47849090521 scopus 로고    scopus 로고
    • Germinal centre-like structures in Wegener's granuloma: The morphological basis for autoimmunity
    • Mueller A, Holl-Ulrich K, Lamprecht P, Gross WL. Germinal centre-like structures in Wegener's granuloma: the morphological basis for autoimmunity Rheumatology (Oxford). 47(8), 1111-1113 (2008).
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.8 , pp. 1111-1113
    • Mueller, A.1    Holl-Ulrich, K.2    Lamprecht, P.3    Gross, W.L.4
  • 20
    • 79953156919 scopus 로고    scopus 로고
    • Nomenclature and classification of vasculitis: Lessons learned from granulomatosis with polyangiitis (Wegener's granulomatosis)
    • Jennette JC. Nomenclature and classification of vasculitis: lessons learned from granulomatosis with polyangiitis (Wegener's granulomatosis). Clin. Exp. Immunol. 164(Suppl. 1), 7-10 (2011).
    • (2011) Clin. Exp. Immunol. , vol.164 , Issue.SUPPL. 1 , pp. 7-10
    • Jennette, J.C.1
  • 21
    • 0030367937 scopus 로고    scopus 로고
    • Proteinase 3, the major autoantigen of Wegener's granulomatosis, enhances IL-8 production by endothelial cells in vitro
    • Berger SP, Seelen MA, Hiemstra PS et al. Proteinase 3, the major autoantigen of Wegener's granulomatosis, enhances IL-8 production by endothelial cells in vitro. J. Am. Soc. Nephrol. 7(5), 694-701 (1996).
    • (1996) J. Am. Soc. Nephrol. , vol.7 , Issue.5 , pp. 694-701
    • Berger, S.P.1    Seelen, M.A.2    Hiemstra, P.S.3
  • 22
    • 0032536533 scopus 로고    scopus 로고
    • Wegener's granulomatosis: Anti-proteinase 3 antibodies are potent inductors of human endothelial cell signaling and leakage response
    • Sibelius U, Hattar K, Schenkel A et al. Wegener's granulomatosis: anti-proteinase 3 antibodies are potent inductors of human endothelial cell signaling and leakage response. J. Exp. Med. 187(4), 497-503 (1998).
    • (1998) J. Exp. Med. , vol.187 , Issue.4 , pp. 497-503
    • Sibelius, U.1    Hattar, K.2    Schenkel, A.3
  • 23
    • 0034668005 scopus 로고    scopus 로고
    • The soluble endothelial protein C receptor binds to activated neutrophils: Involvement of proteinase-3 and CD11b/CD18
    • Kurosawa S, Esmon CT, Stearns-Kurosawa DJ. The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18. J. Immunol. 165(8), 4697-4703 (2000).
    • (2000) J. Immunol. , vol.165 , Issue.8 , pp. 4697-4703
    • Kurosawa, S.1    Esmon, C.T.2    Stearns-Kurosawa, D.J.3
  • 24
    • 40349088701 scopus 로고    scopus 로고
    • New insight into the pathogenesis of vasculitis associated with antineutrophil cytoplasmic autoantibodies
    • Falk, R. J.; Jennette, J. C. New insight into the pathogenesis of vasculitis associated with antineutrophil cytoplasmic autoantibodies. Current Opin. Rheumatol. 20, 55-60, (2008).
    • (2008) Current Opin. Rheumatol. , vol.20 , pp. 55-60
    • Falk, R.J.1    Jennette, J.C.2
  • 25
    • 79953010885 scopus 로고    scopus 로고
    • Pathogenesis of ANCAassociated vasculitides
    • Kallenberg CG. Pathogenesis of ANCAassociated vasculitides. Ann. Rheum. Dis. 70(Suppl. 1), i59-i63 (2011).
    • (2011) Ann. Rheum. Dis. , vol.70 , Issue.SUPPL. 1
    • Kallenberg, C.G.1
  • 26
    • 79957887825 scopus 로고    scopus 로고
    • In vivo approaches to investigate ANCA-Associated vasculitis: Lessons and limitations
    • Heeringa P, Little MA. In vivo approaches to investigate ANCA-Associated vasculitis: lessons and limitations. Arthritis Res. Ther. 13(1), 204 (2011).
    • (2011) Arthritis Res. Ther. , vol.13 , Issue.1 , pp. 204
    • Heeringa, P.1    Little, M.A.2
  • 27
    • 74549179173 scopus 로고    scopus 로고
    • Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis
    • Primo VC, Marusic S, Franklin CC et al. Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis. Clin. Exp. Immunol. 159(3), 327-337 (2010).
    • (2010) Clin. Exp. Immunol. , vol.159 , Issue.3 , pp. 327-337
    • Primo, V.C.1    Marusic, S.2    Franklin, C.C.3
  • 28
    • 84855674846 scopus 로고    scopus 로고
    • Antiproteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system
    • Little MA, Al-Ani B, Ren S et al. Antiproteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system. PLoS ONE 7(1), e28626 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.1
    • Little, M.A.1    Al-Ani, B.2    Ren, S.3
  • 29
    • 84879696654 scopus 로고    scopus 로고
    • PR3 antibodies do not induce renal pathology in a novel PR3-humanized mouse model for Wegener's granulomatosis
    • Relle M, Cash H, Schommers N, Reifenberg K, Galle PR, Schwarting A. PR3 antibodies do not induce renal pathology in a novel PR3-humanized mouse model for Wegener's granulomatosis. Rheumatol. Int. 33(3), 613-622 (2013).
    • (2013) Rheumatol. Int. , vol.33 , Issue.3 , pp. 613-622
    • Relle, M.1    Cash, H.2    Schommers, N.3    Reifenberg, K.4    Galle, P.R.5    Schwarting, A.6
  • 30
    • 53549100724 scopus 로고    scopus 로고
    • Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis
    • Kain R, Exner M, Brandes R et al. Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis. Nat. Med. 14(10), 1088-1096 (2008).
    • (2008) Nat. Med. , vol.14 , Issue.10 , pp. 1088-1096
    • Kain, R.1    Exner, M.2    Brandes, R.3
  • 31
    • 84863230295 scopus 로고    scopus 로고
    • Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis
    • Roth AJ, Brown MC, Smith RN et al. Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis. J. Am. Soc. Nephrol. 23(3), 545-555 (2012).
    • (2012) J. Am. Soc. Nephrol. , vol.23 , Issue.3 , pp. 545-555
    • Roth, A.J.1    Brown, M.C.2    Smith, R.N.3
  • 32
    • 84868632379 scopus 로고    scopus 로고
    • Infectioninduced NETosis is a dynamic process involving neutrophil multitasking in vivo
    • Yipp BG, Petri B, Salina D et al. Infectioninduced NETosis is a dynamic process involving neutrophil multitasking in vivo. Nat. Med. 18(9), 1386-1393 (2012).
    • (2012) Nat. Med. , vol.18 , Issue.9 , pp. 1386-1393
    • Yipp, B.G.1    Petri, B.2    Salina, D.3
  • 33
    • 67349279881 scopus 로고    scopus 로고
    • Netting neutrophils in autoimmune small-vessel vasculitis
    • Kessenbrock K, Krumbholz M, Schönermarck U et al. Netting neutrophils in autoimmune small-vessel vasculitis. Nat. Med. 15(6), 623-625 (2009).
    • (2009) Nat. Med. , vol.15 , Issue.6 , pp. 623-625
    • Kessenbrock, K.1    Krumbholz, M.2    Schönermarck, U.3
  • 34
    • 84867836102 scopus 로고    scopus 로고
    • Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity
    • Sangaletti S, Tripodo C, Chiodoni C et al. Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity. Blood 120(15), 3007-3018 (2012).
    • (2012) Blood , vol.120 , Issue.15 , pp. 3007-3018
    • Sangaletti, S.1    Tripodo, C.2    Chiodoni, C.3
  • 35
    • 84868114208 scopus 로고    scopus 로고
    • Abnormal conformation and impaired degradation of propylthiouracil- induced neutrophil extracellular traps: Implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibody-Associated vasculitis
    • Nakazawa D, Tomaru U, Suzuki A et al. Abnormal conformation and impaired degradation of propylthiouracil-induced neutrophil extracellular traps: implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibody-Associated vasculitis. Arthritis Rheum. 64(11), 3779-3787 (2012).
    • (2012) Arthritis Rheum. , vol.64 , Issue.11 , pp. 3779-3787
    • Nakazawa, D.1    Tomaru, U.2    Suzuki, A.3
  • 36
    • 52049122611 scopus 로고    scopus 로고
    • Proteinase 3, protease-Activated receptor-2 and interleukin-32: Linking innate and autoimmunity in Wegener's granulomatosis
    • Csernok E, Holle JU, Gross WL. Proteinase 3, protease-Activated receptor-2 and interleukin-32: linking innate and autoimmunity in Wegener's granulomatosis. Clin. Exp. Rheumatol. 26(3 Suppl. 49), S112-S117 (2008).
    • (2008) Clin. Exp. Rheumatol. , vol.26 , Issue.3 SUPPL. 49
    • Csernok, E.1    Holle, J.U.2    Gross, W.L.3
  • 37
    • 73649143921 scopus 로고    scopus 로고
    • Interaction of proteinase 3 with its associated partners: Implications in the pathogenesis of Wegener's granulomatosis
    • Witko-Sarsat V, Reuter N, Mouthon L. Interaction of proteinase 3 with its associated partners: implications in the pathogenesis of Wegener's granulomatosis. Curr. Opin. Rheumatol. 22(1), 1-7 (2010).
    • (2010) Curr. Opin. Rheumatol. , vol.22 , Issue.1 , pp. 1-7
    • Witko-Sarsat, V.1    Reuter, N.2    Mouthon, L.3
  • 38
    • 37049006778 scopus 로고    scopus 로고
    • Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: Evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis
    • Kantari C, Pederzoli-Ribeil M, Amir-Moazami O et al. Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis. Blood 110(12), 4086-4095 (2007).
    • (2007) Blood , vol.110 , Issue.12 , pp. 4086-4095
    • Kantari, C.1    Pederzoli-Ribeil, M.2    Amir-Moazami, O.3
  • 39
    • 84867204002 scopus 로고    scopus 로고
    • Distinct genetic subsets in ANCAassociated vasculitis
    • author reply 1471
    • Goldschmeding R, Dolman KM, Hack CE. Distinct genetic subsets in ANCAassociated vasculitis. N. Engl. J. Med. 367(15), 1470; author reply 1471 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , Issue.15 , pp. 1470
    • Goldschmeding, R.1    Dolman, K.M.2    Hack, C.E.3
  • 40
    • 48449084592 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotide stimulates production of anti-neutrophil cytoplasmic antibodies in ANCA associated vasculitis
    • Hurtado PR, Jeffs L, Nitschke J et al. CpG oligodeoxynucleotide stimulates production of anti-neutrophil cytoplasmic antibodies in ANCA associated vasculitis. BMC Immunol. 9, 34 (2008).
    • (2008) BMC Immunol. , vol.9 , pp. 34
    • Hurtado, P.R.1    Jeffs, L.2    Nitschke, J.3
  • 42
    • 77957865413 scopus 로고    scopus 로고
    • B cell abnormalities in Wegener's granulomatosis and microscopic polyangiitis: Role of CD25+-expressing B cells
    • Eriksson P, Sandell C, Backteman K, Ernerudh J. B cell abnormalities in Wegener's granulomatosis and microscopic polyangiitis: role of CD25+-expressing B cells. J. Rheumatol. 37(10), 2086-2095 (2010).
    • (2010) J. Rheumatol. , vol.37 , Issue.10 , pp. 2086-2095
    • Eriksson, P.1    Sandell, C.2    Backteman, K.3    Ernerudh, J.4
  • 43
    • 33745697938 scopus 로고    scopus 로고
    • B lymphocyte maturation in Wegener's granulomatosis: A comparative analysis of VH genes from endonasal lesions
    • Voswinkel J, Mueller A, Kraemer JA et al. B lymphocyte maturation in Wegener's granulomatosis: a comparative analysis of VH genes from endonasal lesions. Ann. Rheum. Dis. 65(7), 859-864 (2006).
    • (2006) Ann. Rheum. Dis. , vol.65 , Issue.7 , pp. 859-864
    • Voswinkel, J.1    Mueller, A.2    Kraemer, J.A.3
  • 44
    • 79151486085 scopus 로고    scopus 로고
    • Wegener's granuloma harbors B lymphocytes with specificities against a proinflammatory transmembrane protein and a tetraspanin
    • Thurner L, Müller A, Cérutti M et al. Wegener's granuloma harbors B lymphocytes with specificities against a proinflammatory transmembrane protein and a tetraspanin. J. Autoimmun. 36(1), 87-90 (2011).
    • (2011) J. Autoimmun. , vol.36 , Issue.1 , pp. 87-90
    • Thurner, L.1    Müller, A.2    Cérutti, M.3
  • 45
    • 48649085976 scopus 로고    scopus 로고
    • Analysis and classification of B-cell infiltrates in lupus and ANCA-Associated nephritis
    • Steinmetz OM, Velden J, Kneissler U et al. Analysis and classification of B-cell infiltrates in lupus and ANCA-Associated nephritis. Kidney Int. 74(4), 448-457 (2008).
    • (2008) Kidney Int. , vol.74 , Issue.4 , pp. 448-457
    • Steinmetz, O.M.1    Velden, J.2    Kneissler, U.3
  • 46
  • 47
    • 58049215481 scopus 로고    scopus 로고
    • CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis
    • Wilde B, Dolff S, Cai X et al. CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis. Nephrol. Dial. Transplant. 24(1), 161-171 (2009).
    • (2009) Nephrol. Dial. Transplant. , vol.24 , Issue.1 , pp. 161-171
    • Wilde, B.1    Dolff, S.2    Cai, X.3
  • 48
    • 69449091010 scopus 로고    scopus 로고
    • Urinary CD4+ effector memory T cells reflect renal disease activity in antineutrophil cytoplasmic antibodyassociated vasculitis
    • Abdulahad WH, Kallenberg CG, Limburg PC, Stegeman CA. Urinary CD4+ effector memory T cells reflect renal disease activity in antineutrophil cytoplasmic antibodyassociated vasculitis. Arthritis Rheum. 60(9), 2830-2838 (2009).
    • (2009) Arthritis Rheum. , vol.60 , Issue.9 , pp. 2830-2838
    • Abdulahad, W.H.1    Kallenberg, C.G.2    Limburg, P.C.3    Stegeman, C.A.4
  • 49
    • 65349124769 scopus 로고    scopus 로고
    • CD45RC isoform expression identifies functionally distinct T cell subsets differentially distributed between healthy individuals and AAV patients
    • Ordonez L, Bernard I, L'faqihi-Olive FE, Tervaert JW, Damoiseaux J, Saoudi A. CD45RC isoform expression identifies functionally distinct T cell subsets differentially distributed between healthy individuals and AAV patients. PLoS ONE 4(4), e5287 (2009).
    • (2009) PLoS ONE , vol.4 , Issue.4
    • Ordonez, L.1    Bernard, I.2    L'Faqihi-Olive, F.E.3    Tervaert, J.W.4    Damoiseaux, J.5    Saoudi, A.6
  • 50
    • 47249092218 scopus 로고    scopus 로고
    • Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission
    • Abdulahad WH, Stegeman CA, Limburg PC, Kallenberg CG. Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission. Arthritis Rheum. 58(7), 2196-2205 (2008).
    • (2008) Arthritis Rheum. , vol.58 , Issue.7 , pp. 2196-2205
    • Abdulahad, W.H.1    Stegeman, C.A.2    Limburg, P.C.3    Kallenberg, C.G.4
  • 51
    • 79960427669 scopus 로고    scopus 로고
    • Distinct proteinase 3-induced cytokine patterns in Wegener's granulomatosis, Churg-Strauss syndrome, and healthy controls
    • Fagin U, Csernok E, Müller A et al. Distinct proteinase 3-induced cytokine patterns in Wegener's granulomatosis, Churg-Strauss syndrome, and healthy controls. Clin. Exp. Rheumatol. 29(1 Suppl. 64), S57-S62 (2011).
    • (2011) Clin. Exp. Rheumatol. , vol.29 , Issue.1 SUPPL. 64
    • Fagin, U.1    Csernok, E.2    Müller, A.3
  • 52
    • 84862588507 scopus 로고    scopus 로고
    • Renal IL-17 expression in human ANCA-Associated glomerulonephritis
    • Velden J, Paust HJ, Hoxha E et al. Renal IL-17 expression in human ANCA-Associated glomerulonephritis. Am. J. Physiol. Renal Physiol. 302(12), F1663-F1673 (2012).
    • (2012) Am. J. Physiol. Renal Physiol. , vol.302 , Issue.12
    • Velden, J.1    Paust, H.J.2    Hoxha, E.3
  • 53
    • 77952990847 scopus 로고    scopus 로고
    • Th17 cells promote autoimmune antimyeloperoxidase glomerulonephritis
    • Gan PY, Steinmetz OM, Tan DS et al. Th17 cells promote autoimmune antimyeloperoxidase glomerulonephritis. J. Am. Soc. Nephrol. 21(6), 925-931 (2010).
    • (2010) J. Am. Soc. Nephrol. , vol.21 , Issue.6 , pp. 925-931
    • Gan, P.Y.1    Steinmetz, O.M.2    Tan, D.S.3
  • 54
    • 84862494308 scopus 로고    scopus 로고
    • Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritis
    • Paust HJ, Turner JE, Riedel JH et al. Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritis. Kidney Int. 82(1), 72-83 (2012).
    • (2012) Kidney Int. , vol.82 , Issue.1 , pp. 72-83
    • Paust, H.J.1    Turner, J.E.2    Riedel, J.H.3
  • 55
    • 20144388308 scopus 로고    scopus 로고
    • Abnormalities of CD4 T cell subpopulations in ANCA-Associated vasculitis
    • Marinaki S, Neumann I, Kälsch AI et al. Abnormalities of CD4 T cell subpopulations in ANCA-Associated vasculitis. Clin. Exp. Immunol. 140(1), 181-191 (2005).
    • (2005) Clin. Exp. Immunol. , vol.140 , Issue.1 , pp. 181-191
    • Marinaki, S.1    Neumann, I.2    Kälsch, A.I.3
  • 58
    • 77950514849 scopus 로고    scopus 로고
    • Patients with Wegener's granulomatosis demonstrate a relative deficiency and functional impairment of T-regulatory cells
    • Morgan MD, Day CJ, Piper KP et al. Patients with Wegener's granulomatosis demonstrate a relative deficiency and functional impairment of T-regulatory cells. Immunology 130(1), 64-73 (2010).
    • (2010) Immunology , vol.130 , Issue.1 , pp. 64-73
    • Morgan, M.D.1    Day, C.J.2    Piper, K.P.3


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