Hepatitis B DNA vaccine-polycation nano-complexes enhancing immune response by percutaneous administration with microneedle

Biological and Pharmaceutical Bulletin

Volumn 36, Issue 8, 2013, Pages 1283-1291

  Yin, Dongfeng ^a,c   Liang, Wenqing ^b   Xing, Shuxing ^a   Gao, Zhixiang ^c   Zhang, Wei ^c   Guo, Zhili ^c   Gao, Shen ^c  

^a Urumqi General Hospital   (China)

^b SHAOXING PEOPLE S HOSPITAL   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Hepatitis B DNA vaccine; Microneedle; Nano complex; Percutaneous immune; Pluronic P123 modified polyethyleneimine

Indexed keywords

GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; IMMUNOGLOBULIN G; NANOPARTICLE; POLOXAMER; POLYETHYLENEIMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ANTIGEN PRESENTING CELL; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG UPTAKE; EPIDERMIS; FEMALE; GENE VECTOR; HAIR FOLLICLE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; MICRONEEDLE; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; SKIN PENETRATION; STRATUM CORNEUM; SYNTHESIS; ZETA POTENTIAL;

EID: 84883200805     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00050     Document Type: Article

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