Inhibition of EGF signaling protects the diabetic retina from insulin-induced vascular leakage

American Journal of Pathology

Volumn 183, Issue 3, 2013, Pages 987-995

  Sugimoto, Masahiko ^a   Cutler, Alecia ^a   Shen, Bailey ^a   Moss, Scot E ^b   Iyengar, Sudha K ^a,c   Klein, Ronald ^b   Folkman, Judah ^d   Anand Apte, Bela ^a  

^a CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ADAM10 ENDOPEPTIDASE; BETACELLULIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; DISEASE COURSE; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; METABOLIC REGULATION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA MACULA EDEMA; SIGNAL TRANSDUCTION; TIGHT JUNCTION; VASCULAR DISEASE; VASCULAR LEAKAGE; VISUAL IMPAIRMENT;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOOD VESSELS; CAPILLARY PERMEABILITY; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; INSULIN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MACULAR EDEMA; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PROTECTIVE AGENTS; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETINA; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS;

EID: 84883188106     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.05.017     Document Type: Article

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