Betacellulin and amphiregulin induce upregulation of cyclin D1 and DNA synthesis activity through differential signaling pathways in vascular smooth muscle cells

Circulation Research

Volumn 93, Issue 4, 2003, Pages 302-310

  Shin, Hyoung Seek ^a   Lee, Hyo Jeong ^b   Nishida, Makoto ^c   Lee, Mi Sook ^a   Tamura, Ritsu ^c   Yamashita, Shizuya ^c   Matsuzawa, Yuji ^c   Lee, In Kyu ^b   Koh, Gou Young ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Keimyung University School of Medicine   (South Korea)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amphiregulin; Betacellulin; Epidermal growth factor receptors; Extracellular signal regulated kinase 1 and 2; Phosphatidylinositol 3 kinase

Indexed keywords

AMPHIREGULIN; BETACELLULIN; CELL DNA; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ERB2; PROTEIN ERB3; PROTEIN ERB4; PROTEIN KINASE B; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

ARTERIOSCLEROSIS; BETA CATENIN; CELL CYCLE; CELL NUCLEUS; CELLS, CULTURED; CYCLIN D1; CYTOSKELETAL PROTEINS; DNA; DNA-BINDING PROTEINS; EPIDERMAL GROWTH FACTOR; ETS-DOMAIN PROTEIN ELK-1; FORKHEAD TRANSCRIPTION FACTORS; GLYCOGEN SYNTHASE KINASE 3; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 0041356915     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000086803.64109.9E     Document Type: Article

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