Clostridium scindens: A human gut microbe with a high potential to convert glucocorticoids into androgens

Journal of Lipid Research

Volumn 54, Issue 9, 2013, Pages 2437-2449

  Ridlon, Jason M ^a,b   Ikegawa, Shigeo ^c   Alves, João M P ^a   Zhou, Biao ^d   Kobayashi, Akiko ^d   Iida, Takashi ^d   Mitamura, Kuniko ^c   Tanabe, Genzoh ^c   Serrano, Myrna ^a,b   De Guzman, Ainee ^e   Cooper, Patsy ^b   Buck, Gregory A ^a,b   Hylemon, Phillip B ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b Endocrinology and Metabolism Section   (United States)

^c KINKI UNIVERSITY   (Japan)

^d NIHON UNIVERSITY   (Japan)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Microbiome; RNA Seq; Steroid

Indexed keywords

11BETA HYDROXYANDROSTENEDIONE; 20ALPHA HYDROXYSTEROID DEHYDROGENASE; ANDROGEN; CARRIER PROTEIN; CORTICOSTEROID TRANSPORTER; GENOMIC DNA; GLUCOCORTICOID; HYDROCORTISONE; MESSENGER RNA; OXIDOREDUCTASE; STEROID 17ALPHA MONOOXYGENASE; THREONINE 3 DEHYDROGENASE; TRANSKETOLASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; CARBON NUCLEAR MAGNETIC RESONANCE; CARBON SOURCE; CHEMICAL STRUCTURE; CLOSTRIDIUM; CLOSTRIDIUM SCINDENS; CONTROLLED STUDY; DES C GENE; DESAB GENE; DESD GENE; ENZYME PURIFICATION; GENE FUNCTION; GENE OVEREXPRESSION; HORMONE METABOLISM; INTESTINE FLORA; MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PENTOSE PHOSPHATE CYCLE; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RNA SEQUENCE; SIDE CHAIN CLEAVAGE; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; X RAY CRYSTALLOGRAPHY;

MICROBIOME; RNA-SEQ; STEROID;

ANDROGENS; ANDROSTENEDIONE; CLOSTRIDIUM; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; HYDROXYSTEROID DEHYDROGENASES; INTESTINES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OPERON; RNA, MESSENGER; STEROID 17-ALPHA-HYDROXYLASE;

EID: 84883179071     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M038869     Document Type: Article

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