In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 7, 2013, Pages

  Matsen, Miles E ^a   Thaler, Joshua P ^a   Wisse, Brent E ^a   Guyenet, Stephan J ^a   Meek, Thomas H ^a   Ogimoto, Kayoko ^a   Cubelo, Alex ^a   Fischer, Jonathan D ^a   Kaiyala, Karl J ^a   Schwartz, Michael W ^a   Morton, Gregory J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Brown adipose tissue; Diabetes; Glucose uptake; Sympathetic nervous system; Thyroid

Indexed keywords

LEPTIN; LIOTHYRONINE; MESSENGER RNA; SOBETIROME; THYROID HORMONE RECEPTOR; THYROXINE; UNCOUPLING PROTEIN 1; ACETIC ACID DERIVATIVE; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; GC 1 COMPOUND; GLUCOSE; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; PHENOL DERIVATIVE; STREPTOZOCIN; THYROID HORMONE RECEPTOR BETA;

ADIPOSE TISSUE; ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY EXPENDITURE; EUTHYROID SICK SYNDROME; FAT MASS; FOOD INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HYPERGLYCEMIA; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYMPATHETIC FUNCTION; THERMOGENESIS; THYROID FUNCTION TEST; THYROXINE BLOOD LEVEL; WEIGHT REDUCTION; ANIMAL; BODY COMPOSITION; BROWN ADIPOSE TISSUE; DRUG EFFECT; DRUG POTENTIATION; EATING; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ACETATES; ADIPOSE TISSUE, BROWN; ADRENERGIC BETA-3 RECEPTOR AGONISTS; ANIMALS; BODY COMPOSITION; DIABETES MELLITUS, EXPERIMENTAL; EATING; GLUCOSE; HYPERGLYCEMIA; ION CHANNELS; MALE; MITOCHONDRIAL PROTEINS; PHENOLS; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-3; STREPTOZOCIN; SYMPATHETIC NERVOUS SYSTEM; THERMOGENESIS; THYROID HORMONE RECEPTORS BETA; TRIIODOTHYRONINE;

MLCS; MLOWN;

EID: 84878199366     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00488.2012     Document Type: Article

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