A switch III motif relays signaling between a B12 enzyme and its G-protein chaperone

Nature Chemical Biology

Volumn 9, Issue 9, 2013, Pages 535-541

  Lofgren, Michael ^a   Padovani, Dominique ^a,c   Koutmos, Markos ^b   Banerjee, Ruma ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; B12 ENZYME; CHAPERONE; COBAMAMIDE; ENZYME; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; GUANYLYLIMIDODIPHOSPHATE; MEAB PROTEIN; METHYLMALONYL COENZYME A MUTASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MUTAGENESIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PURIFICATION; GENE MUTATION; HYDROLYSIS; METHYLMALONIC ACIDURIA; METHYLOBACTERIUM EXTORQUENS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; SWITCH III MOTIF; TURNOVER TIME;

AMINO ACID MOTIFS; GTP-BINDING PROTEINS; HUMANS; METHYLMALONYL-COA MUTASE; MOLECULAR CHAPERONES; SIGNAL TRANSDUCTION; VITAMIN B 12;

EID: 84883170355     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1298     Document Type: Article

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