Redundancy in the pathway for redox regulation of mammalian methionine synthase. Reductive activation by the dual flavoprotein, novel reductase 1

Journal of Biological Chemistry

Volumn 278, Issue 40, 2003, Pages 38310-38314

  Olteanu, Horatiu ^a   Banerjee, Ruma ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; GENETIC ENGINEERING; PROTEINS; STOICHIOMETRY;

REDOX SYSTEMS;

ENZYME KINETICS;

5 METHYLTETRAHYDROFOLIC ACID; COBALAMIN; CYTOCHROME B5; CYTOCHROME P450 REDUCTASE; FLAVOPROTEIN; HOMOCYSTEINE; METHIONINE; METHIONINE SYNTHASE; METHYL GROUP; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TETRAHYDROFOLIC ACID;

ARTICLE; ENZYME ACTIVATION; ENZYME MECHANISM; HYPERHOMOCYSTEINEMIA; METHYLATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; REGULATORY MECHANISM; STOICHIOMETRY;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; CLONING, MOLECULAR; CYTOCHROME C GROUP; CYTOCHROMES B5; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; FLAVOPROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HOMOCYSTEINE; HUMANS; IONS; KINETICS; MODELS, BIOLOGICAL; NADP; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; OXIDOREDUCTASES; PEPTIDES; RECOMBINANT PROTEINS; ULTRAVIOLET RAYS;

MAMMALIA;

EID: 0141643321     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306282200     Document Type: Article

References (26)

1. Matthews, R. G. (2001) Acc. Chem. Res. 34, 681-689
2. Banerjee, R., and Ragsdale, S. W. (2003) Ann. Rev. Biochem. 72, 209-247
3. Refsum, H., Ueland, P. M., Nygard, O., and Vollset, S. E. (1998) Annu. Rev. Medicine. 49, 31-62
4. Rosenblatt, D. S. (1995) in Inherited Disorders of Folate Transport and Me. tabolism: The Metabolic and Molecular Bases of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., eds) McGraw Hill, New York
5. Swanson, D. A., Liu, M. L., Baker, P. J., Garrett, L., Stitzel, M., Wu, J., Harris, M., Banerjee, R., Shane, B., and Brody, L. C. (2001) Mol. Cell. Biol. 21, 1058-1065
6. Fujii, K., Galivan, J. H., and Huennekens, F. M. (1977) Arch. Biochem. Biophys. 178, 662-670
7. Fujii, K., and Huennekens, F. M. (1974) J. Biol. Chem. 249, 6745-6753
8. Leclerc, D., Wilson, A., Dumas, R., Gafuik, C., Song, D., Watkins, D., Heng, H. H. Q., Rommens, J. M., Scherer, S. W., Rosenblatt, D. S., and Gravel, R. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3059-3064
9. Chen, Z., and Banerjee, R. (1998) J. Biol. Chem. 273, 26248-26255
10. Paine, M. J., Garner, A. P., Powell, D., Sibbald, J., Sales, M., Pratt, N., Smith, T., Tew, D. G., and Wolf, C. R. (2000) J. Biol. Chem. 275, 1471-1478
11. Olteanu, H., and Banerjee, R. (2001) J. Biol. Chem. 276, 35558-35563
12. Wilson, A., Leclerc, D., Rosenblatt, D. S., and Gravel, R. A. (1999) Hum. Mol. Genet. 8, 2009-2016
13. Fowler, B., Suormala, T., Gunther, M., Till, J., and Wraith, J. E. (1997) J. Inherit. Metab. Dis. 20, 21
14. Wolthers, K. R., Basran, J., Munro, A. W., and Scrutton, N. S. (2003) Biochemistry 42, 3911-3920
15. Li, Y. N., Gulati, S., Baker, P. J., Brody, L. C., Banerjee, R., and Kruger, W. D. (1996) Hum. Mol. Genet. 5, 1851-1858
16. Banerjee, R., Gulati, S., and Chen, Z. (1997) Methods Enzymol. 281, 189-196
17. Perrin, D. D., and Dempsey, B. (1974) Buffers for pH and Metal Ion Control, Chapman and Hall, London
18. Chen, Z., Crippen, K., Gulati, S., and Banerjee, R. (1994) J. Biol. Chem. 269, 27193-27197
19. Finn, R. D., Basran, J., Roitel, O., Wolf, C. R., Munro, A. W., Paine, M. J., and Scrutton, N. S. (2003) Eur. J. Biochem. 270, 1164-1175
20. Gulati, S. G., Baker, P., Fowler, B., Li, Y., Kruger, W., Brody, L. C., and Banerjee, R. (1996) Hum. Mol. Genet. 5, 1859-1866
21. Leclerc, D., Campeau, E., Goyette, P., Adjalla, C. E., Christensen, B., Ross, M., Eydoux, P., Rosenblatt, D. S., Rozen, R., and Gravel, R. A. (1996) Hum. Mol. Genet. 5, 1867-1874
22. Wilson, A., Leclerc, D., Saberi, F., Campeau, E., Hwang, H. Y., Shane, B., Phillips, J. A., III, Rosenblatt, D. S., and Gravel, R. A. (1998) Am. J. Hum. Genet. 63, 409-414
23. Willard, H. F., Mellman, I. S., and Rosenberg, L. E. (1978) Am. J. Hum. Genet. 30, 1-13
24. Chen, Z., Chakraborty, S., and Banerjee, R. (1995) J. Biol. Chem. 270, 19246-19249
25. Lexa, D., and Saveant, J.-M. (1983) Acc. Chem. Res. 16, 235-243
26. Banerjee, R. V., Harder, S. R., Ragsdale, S. W., and Matthews, R. G. (1990) Biochemistry 29, 1129-1137